3M4V
 
 | | Crystal structure of the A330P mutant of cytochrome P450 BM3 | | Descriptor: | Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Yang, W, Whitehouse, C.J.C, Bell, S.G, Bartlam, M, Wong, L.L, Rao, Z. | | Deposit date: | 2010-03-12 | | Release date: | 2011-03-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for the properties of two single-site proline mutants of CYP102A1 (P450BM3)
Chembiochem, 11, 2010
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3K5N
 | | Crystal structure of E.coli Pol II-abasic DNA binary complex | | Descriptor: | DNA (5'-D(*GP*TP*CP*CP*TP*GP*(3DR)*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*G)-3'), DNA polymerase II | | Authors: | Yang, W, Wang, F. | | Deposit date: | 2009-10-07 | | Release date: | 2010-02-02 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.), 139, 2009
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3K5M
 | | Crystal structure of E.coli Pol II-abasic DNA-ddGTP Lt(-2, 2) ternary complex | | Descriptor: | 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*TP*CP*CP*TP*GP*(3DR)P*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... | | Authors: | Yang, W, Wang, F. | | Deposit date: | 2009-10-07 | | Release date: | 2010-02-02 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.), 139, 2009
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3K57
 | | Crystal structure of E.coli Pol II-normal DNA-dATP ternary complex | | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*G*TP*AP*TP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*G)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), ... | | Authors: | Yang, W, Wang, F. | | Deposit date: | 2009-10-06 | | Release date: | 2010-02-09 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
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3K59
 | | Crystal structure of E.coli Pol II-normal DNA-dCTP ternary complex | | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*GP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... | | Authors: | Yang, W, Wang, F. | | Deposit date: | 2009-10-06 | | Release date: | 2010-02-09 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
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3K5O
 | | Crystal structure of E.coli Pol II | | Descriptor: | DNA polymerase II | | Authors: | Yang, W, Wang, F. | | Deposit date: | 2009-10-07 | | Release date: | 2010-02-02 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.), 139, 2009
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3K58
 | | Crystal structure of E.coli Pol II-normal DNA-dTTP ternary complex | | Descriptor: | DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*AP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), DNA polymerase II, ... | | Authors: | Yang, W, Wang, F. | | Deposit date: | 2009-10-06 | | Release date: | 2010-02-09 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural insight into translesion synthesis by DNA Pol II
Cell(Cambridge,Mass.), 139, 2009
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3K5L
 | | Crystal structure of E.coli Pol II-abasic DNA-dATP Lt(0, 3) ternary complex | | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*TP*(3DR)P*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... | | Authors: | Yang, W, Wang, F. | | Deposit date: | 2009-10-07 | | Release date: | 2010-02-02 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural insight into translesion synthesis by DNA Pol II.
Cell(Cambridge,Mass.), 139, 2009
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3THW
 | | Human MutSbeta complexed with an IDL of 4 bases (Loop4) and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA Loop4 hairpin, DNA mismatch repair protein Msh2, ... | | Authors: | Yang, W. | | Deposit date: | 2011-08-19 | | Release date: | 2011-12-21 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.09 Å) | | Cite: | Mechanism of mismatch recognition revealed by human MutSbeta bound to unpaired DNA loops
Nat.Struct.Mol.Biol., 19, 2012
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3THY
 | | Human MutSbeta complexed with an IDL of 2 bases (Loop2) and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA Loop2 minus strand, DNA Loop2 plus strand, ... | | Authors: | Yang, W. | | Deposit date: | 2011-08-19 | | Release date: | 2011-12-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.894 Å) | | Cite: | Mechanism of mismatch repair revealed by human MutSbeta bound to unpaired DNA loops
Nat.Struct.Mol.Biol., 19, 2012
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3THX
 | | Human MutSbeta complexed with an IDL of 3 bases (Loop3) and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA Loop3 minus strand, DNA Loop3 plus strand, ... | | Authors: | Yang, W. | | Deposit date: | 2011-08-19 | | Release date: | 2011-12-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Mechanism of mismatch recognition revealed by human MutSbeta bound to unpaired DNA loops
Nat.Struct.Mol.Biol., 19, 2012
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3THZ
 | | Human MutSbeta complexed with an IDL of 6 bases (Loop6) and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA Loop6 minus strand, DNA Loop6 plus strand, ... | | Authors: | Yang, W. | | Deposit date: | 2011-08-19 | | Release date: | 2011-12-21 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (4.3 Å) | | Cite: | Mechanism of mismatch repair revealed by human MutS bound to unpaired DNA loops
Nat.Struct.Mol.Biol., 19, 2012
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8T7P
 | | X-ray crystal structure of PfA-M1(M462S) | | Descriptor: | Aminopeptidase N, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Yang, W, Drinkwater, N, Webb, C.T, McGowan, S. | | Deposit date: | 2023-06-21 | | Release date: | 2024-06-26 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Conformational dynamics of the Plasmodium falciparum M1 aminopeptidase.
To Be Published
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2IS1
 | | Crystal structure of UvrD-DNA-SO4 complex | | Descriptor: | 5'-D(*CP*GP*AP*GP*CP*AP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*TP*GP*CP*TP*CP*GP*TP*TP*TP*TP*TP*TP*T)-3', DNA helicase II, ... | | Authors: | Yang, W, Lee, J.Y. | | Deposit date: | 2006-10-16 | | Release date: | 2007-01-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke.
Cell(Cambridge,Mass.), 127, 2006
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2IS6
 | | Crystal structure of UvrD-DNA-ADPMgF3 ternary complex | | Descriptor: | 5'-D(*CP*GP*AP*GP*CP*AP*CP*TP*GP*CP*AP*GP*TP*GP*CP*TP*CP*GP*TP*TP*GP*TP*TP*AP*T)-3', ADENOSINE-5'-DIPHOSPHATE, DNA helicase II, ... | | Authors: | Yang, W, Lee, J.Y. | | Deposit date: | 2006-10-16 | | Release date: | 2007-01-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke.
Cell(Cambridge,Mass.), 127, 2006
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2IS2
 | | Crystal structure of UvrD-DNA binary complex | | Descriptor: | 33-MER, DNA helicase II, FORMIC ACID, ... | | Authors: | Yang, W, Lee, J.Y. | | Deposit date: | 2006-10-16 | | Release date: | 2007-01-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke.
Cell(Cambridge,Mass.), 127, 2006
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2IS4
 | | Crystal structure of UvrD-DNA-ADPNP ternary complex | | Descriptor: | 25-MER, DNA helicase II, MAGNESIUM ION, ... | | Authors: | Yang, W, Lee, J.Y. | | Deposit date: | 2006-10-16 | | Release date: | 2007-01-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke.
Cell(Cambridge,Mass.), 127, 2006
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2AZO
 | | DNA MISMATCH REPAIR PROTEIN MUTH FROM E. COLI | | Descriptor: | MUTH | | Authors: | Yang, W. | | Deposit date: | 1997-11-20 | | Release date: | 1998-05-20 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for MutH activation in E.coli mismatch repair and relationship of MutH to restriction endonucleases.
EMBO J., 17, 1998
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1AZO
 | | DNA MISMATCH REPAIR PROTEIN MUTH FROM E. COLI | | Descriptor: | 1,2-ETHANEDIOL, MUTH | | Authors: | Yang, W. | | Deposit date: | 1997-11-19 | | Release date: | 1998-05-20 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural basis for MutH activation in E.coli mismatch repair and relationship of MutH to restriction endonucleases.
EMBO J., 17, 1998
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1B63
 | | MUTL COMPLEXED WITH ADPNP | | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, MUTL, ... | | Authors: | Yang, W. | | Deposit date: | 1999-01-20 | | Release date: | 1999-06-08 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Transformation of MutL by ATP binding and hydrolysis: a switch in DNA mismatch repair.
Cell(Cambridge,Mass.), 97, 1999
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1BKN
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7VMB
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2V83
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2V87
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1S0M
 | | Crystal structure of a Benzo[a]pyrene Diol Epoxide adduct in a ternary complex with a DNA polymerase | | Descriptor: | 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*T)-3', ... | | Authors: | Ling, H, Sayer, J.M, Boudsocq, F, Plosky, B.S, Woodgate, R, Yang, W. | | Deposit date: | 2003-12-31 | | Release date: | 2004-03-30 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase.
Proc.Natl.Acad.Sci.USA, 101, 2004
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