1E96
| Structure of the Rac/p67phox complex | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, NEUTROPHIL CYTOSOL FACTOR 2 (NCF-2) TPR DOMAIN, ... | Authors: | Lapouge, K, Smith, S.J.M, Walker, P.A, Gamblin, S.J, Smerdon, S.J, Rittinger, K. | Deposit date: | 2000-10-10 | Release date: | 2000-11-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of the TPR domain of p67phox in complex with Rac.GTP. Mol.Cell, 6, 2000
|
|
3UN0
| Crystal Structure of MDC1 FHA Domain | Descriptor: | Mediator of DNA damage checkpoint protein 1, SULFATE ION | Authors: | Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J. | Deposit date: | 2011-11-15 | Release date: | 2011-12-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator. Nucleic Acids Res., 40, 2012
|
|
3UOT
| Crystal Structure of MDC1 FHA Domain in Complex with a Phosphorylated Peptide from the MDC1 N-terminus | Descriptor: | Mediator of DNA damage checkpoint protein 1 | Authors: | Clapperton, J.A, Lloyd, J, Haire, L.F, Li, J, Smerdon, S.J. | Deposit date: | 2011-11-17 | Release date: | 2011-12-28 | Last modified: | 2012-07-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator. Nucleic Acids Res., 40, 2012
|
|
3I0M
| Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain | Descriptor: | DNA repair and telomere maintenance protein nbs1, GLYCEROL | Authors: | Clapperton, J.A, Lloyd, J, Chapman, J.R, Jackson, S.P, Smerdon, S.J. | Deposit date: | 2009-06-25 | Release date: | 2009-10-13 | Last modified: | 2012-05-02 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage Cell(Cambridge,Mass.), 139, 2009
|
|
3I0N
| Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain | Descriptor: | DNA repair and telomere maintenance protein nbs1, GLYCEROL | Authors: | Clapperton, J.A, Lloyd, J, Chapman, J.R, Jackson, S.P, Smerdon, S.J. | Deposit date: | 2009-06-25 | Release date: | 2009-10-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage Cell(Cambridge,Mass.), 139, 2009
|
|
1AM4
| COMPLEX BETWEEN CDC42HS.GMPPNP AND P50 RHOGAP (H. SAPIENS) | Descriptor: | CDC42HS, MAGNESIUM ION, P50-RHOGAP, ... | Authors: | Rittinger, K, Walker, P, Gamblin, S.J, Smerdon, S.J. | Deposit date: | 1997-06-22 | Release date: | 1998-07-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP. Nature, 388, 1997
|
|
1EYV
| THE CRYSTAL STRUCTURE OF NUSB FROM MYCOBACTERIUM TUBERCULOSIS | Descriptor: | N-UTILIZING SUBSTANCE PROTEIN B HOMOLOG, PHOSPHATE ION | Authors: | Gopal, B, Haire, L.F, Cox, R.A, Colston, M.J, Major, S, Brannigan, J.A, Smerdon, S.J, Dodson, G.G, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2000-05-09 | Release date: | 2000-05-18 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The crystal structure of NusB from Mycobacterium tuberculosis. Nat.Struct.Biol., 7, 2000
|
|
1GXC
| FHA domain from human Chk2 kinase in complex with a synthetic phosphopeptide | Descriptor: | SERINE/THREONINE-PROTEIN KINASE CHK2, SYNTHETIC PHOSPHOPEPTIDE | Authors: | Li, J, Williams, B.L, Haire, L.F, Goldberg, M, Wilker, E, Durocher, D, Yaffe, M.B, Jackson, S.P, Smerdon, S.J. | Deposit date: | 2002-04-02 | Release date: | 2002-06-13 | Last modified: | 2016-12-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and Functional Versatility of the Fha Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2 Mol.Cell, 9, 2002
|
|
1TX4
| RHO/RHOGAP/GDP(DOT)ALF4 COMPLEX | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, P50-RHOGAP, ... | Authors: | Rittinger, K, Walker, P.A, Smerdon, S.J, Gamblin, S.J. | Deposit date: | 1997-07-29 | Release date: | 1998-09-16 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue. Nature, 389, 1997
|
|
1RGP
| GTPASE-ACTIVATION DOMAIN FROM RHOGAP | Descriptor: | RHOGAP | Authors: | Barrett, T, Xiao, B, Dodson, E.J, Dodson, G, Ludbrook, S.B, Nurmahomed, K, Gamblin, S.J, Musacchio, A, Smerdon, S.J, Eccleston, J.F. | Deposit date: | 1996-12-05 | Release date: | 1997-10-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of the GTPase-activating domain from p50rhoGAP. Nature, 385, 1997
|
|
1QJB
| 14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 1) | Descriptor: | 14-3-3 PROTEIN ZETA/DELTA, PHOSPHOPEPTIDE | Authors: | Rittinger, K, Budman, J, Xu, J, Volinia, S, Cantley, L.C, Smerdon, S.J, Gamblin, S.J, Yaffe, M.B. | Deposit date: | 1999-06-23 | Release date: | 1999-09-15 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Analysis of 14-3-3 Phosphopeptide Complexes Identifies a Dual Role for the Nuclear Export Signal of 14-3-3 in Ligand Binding Mol.Cell, 4, 1999
|
|
1QJA
| 14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 2) | Descriptor: | 14-3-3 PROTEIN ZETA, PHOSPHOPEPTIDE | Authors: | Rittinger, K, Budman, J, Xu, J, Volinia, S, Cantley, L.C, Smerdon, S.J, Gamblin, S.J, Yaffe, M.B. | Deposit date: | 1999-06-23 | Release date: | 1999-09-15 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Analysis of 14-3-3 Phosphopeptide Complexes Identifies a Dual Role for the Nuclear Export Signal of 14-3-3 in Ligand Binding Mol.Cell, 4, 1999
|
|
1OW3
| Crystal Structure of RhoA.GDP.MgF3-in Complex with RhoGAP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho-GTPase-activating protein 1, ... | Authors: | Graham, D.L, Lowe, P.N, Grime, G.W, Marsh, M, Rittinger, K, Smerdon, S.J, Gamblin, S.J, Eccleston, J.F. | Deposit date: | 2003-03-28 | Release date: | 2003-05-06 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | MgF(3)(-) as a Transition State Analog of Phosphoryl Transfer Chem.Biol., 9, 2002
|
|
3POA
| |
3PO8
| |
1I4T
| CRYSTAL STRUCTURE ANALYSIS OF RAC1-GMPPNP IN COMPLEX WITH ARFAPTIN | Descriptor: | ARFAPTIN 2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Tarricone, C, Xiao, B, Justin, N, Gamblin, S.J, Smerdon, S.J. | Deposit date: | 2001-02-23 | Release date: | 2001-05-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways. Nature, 411, 2001
|
|
1I4D
| CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP COMPLEXED WITH ARFAPTIN (P21) | Descriptor: | ARFAPTIN 2, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Tarricone, C, Xiao, B, Justin, N, Gamblin, S.J, Smerdon, S.J. | Deposit date: | 2001-02-20 | Release date: | 2001-05-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways. Nature, 411, 2001
|
|
1I49
| CRYSTAL STRUCTURE ANALYSIS OF ARFAPTIN | Descriptor: | ARFAPTIN 2 | Authors: | Tarricone, C, Xiao, B, Justin, N, Gamblin, S.J, Smerdon, S.J. | Deposit date: | 2001-02-20 | Release date: | 2001-05-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways. Nature, 411, 2001
|
|
1I4L
| CRYSTAL STRUCTURE ANALYSIS OF RAC1-GDP IN COMPLEX WITH ARFAPTIN (P41) | Descriptor: | ARFAPTIN 2, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Tarricone, C, Xiao, B, Justin, N, Gamblin, S.J, Smerdon, S.J. | Deposit date: | 2001-02-22 | Release date: | 2001-05-16 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways. Nature, 411, 2001
|
|
1U7K
| Structure of a hexameric N-terminal domain from murine leukemia virus capsid | Descriptor: | Gag polyprotein | Authors: | Mortuza, G.B, Haire, L.F, Stevens, A, Smerdon, S.J, Stoye, J.P, Taylor, I.A. | Deposit date: | 2004-08-04 | Release date: | 2004-10-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | High-resolution structure of a retroviral capsid hexameric amino-terminal domain. Nature, 431, 2004
|
|
1UMW
| Structure of a human Plk1 Polo-box domain/phosphopeptide complex | Descriptor: | PEPTIDE, SERINE/THREONINE-PROTEIN KINASE PLK | Authors: | Rellos, P, Elia, A, Yaffe, M.B, Smerdon, S.J. | Deposit date: | 2003-08-29 | Release date: | 2003-10-16 | Last modified: | 2017-02-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The Molecular Basis for Phosphodependent Substrate Targeting and Regulation of Plks by the Polo-Box Domain Cell(Cambridge,Mass.), 115, 2003
|
|
1T15
| Crystal Structure of the Brca1 BRCT Domains in Complex with the Phosphorylated Interacting Region from Bach1 Helicase | Descriptor: | BRCA1 interacting protein C-terminal helicase 1, Breast cancer type 1 susceptibility protein | Authors: | Clapperton, J.A, Manke, I.A, Lowery, D.M, Ho, T, Haire, L.F, Yaffe, M.B, Smerdon, S.J. | Deposit date: | 2004-04-15 | Release date: | 2004-05-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer Nat.Struct.Mol.Biol., 11, 2004
|
|
1SW6
| |
1OV3
| Structure of the p22phox-p47phox complex | Descriptor: | Flavocytochrome b558 alpha polypeptide, Neutrophil cytosol factor 1 | Authors: | Groemping, Y, Lapouge, K, Smerdon, S.J, Rittinger, K. | Deposit date: | 2003-03-25 | Release date: | 2003-05-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular basis of phosphorylation-induced activation of the NADPH oxidase Cell(Cambridge,Mass.), 113, 2003
|
|
1NG2
| Structure of autoinhibited p47phox | Descriptor: | Neutrophil cytosolic factor 1 | Authors: | Groemping, Y, Lapouge, K, Smerdon, S.J, Rittinger, K. | Deposit date: | 2002-12-16 | Release date: | 2003-05-20 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Molecular basis of phosphorylation-induced activation of the NADPH oxidase Cell(Cambridge,Mass.), 113, 2003
|
|