8G6M
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![BU of 8g6m by Molmil](/molmil-images/mine/8g6m) | HIV-1 CA lattice bound to IP6, pH 7.4 | Descriptor: | Capsid protein | Authors: | Highland, C.M, Dick, R.A. | Deposit date: | 2023-02-15 | Release date: | 2023-05-03 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM. Proc.Natl.Acad.Sci.USA, 120, 2023
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8G6N
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![BU of 8g6n by Molmil](/molmil-images/mine/8g6n) | HIV-1 capsid lattice bound to dNTPs | Descriptor: | Capsid protein | Authors: | Highland, C.M, Dick, R.A. | Deposit date: | 2023-02-15 | Release date: | 2023-05-03 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM. Proc.Natl.Acad.Sci.USA, 120, 2023
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8CKW
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![BU of 8ckw by Molmil](/molmil-images/mine/8ckw) | |
8CL4
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![BU of 8cl4 by Molmil](/molmil-images/mine/8cl4) | |
8SVC
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![BU of 8svc by Molmil](/molmil-images/mine/8svc) | Crystal Structure of SBP from Klebsiella pneumoniae | Descriptor: | Metal ABC transporter substrate-binding protein, SULFATE ION, ZINC ION | Authors: | Giles, M.W, Cole, G.B, Ng, D, McDevitt, C.A, Moraes, T.F. | Deposit date: | 2023-05-16 | Release date: | 2024-01-24 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Zinc acquisition and its contribution to Klebsiella pneumoniae virulence. Front Cell Infect Microbiol, 13, 2023
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7SU6
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![BU of 7su6 by Molmil](/molmil-images/mine/7su6) | DIHYDRONEOPTERIN ALDOLASE (DHNA) Lys98Ala FROM YERSINIA PESTIS CO-CRYSTALLIZED with 7,8-dihydroneopterin | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-7,8-DIHYDRO-6-(1,2,3-TRIHYDROXYPROPYL)-4(1H)-PTERIDINONE, 7,8-dihydroneopterin aldolase | Authors: | Bourne, C.R. | Deposit date: | 2021-11-16 | Release date: | 2022-12-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | DIHYDRONEOPTERIN ALDOLASE (DHNA) Lys98Ala FROM YERSINIA PESTIS CO-CRYSTALLIZED with 7,8-dihydroneopterin To Be Published
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7SU4
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![BU of 7su4 by Molmil](/molmil-images/mine/7su4) | Dihydroneopterin aldolase (DHNA) Tyr53Phe from Yersinia pestis co-crystallized with 7,8-dihydroneopterin | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-AMINO-7,8-DIHYDRO-6-(1,2,3-TRIHYDROXYPROPYL)-4(1H)-PTERIDINONE, 7,8-dihydroneopterin aldolase, ... | Authors: | Bourne, C.R. | Deposit date: | 2021-11-16 | Release date: | 2022-12-28 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Dihydroneopterin aldolase (DHNA) Tyr53Phe from Yersinia pestis co-crystallized with 7,8-dihydroneopterin To Be Published
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6OUG
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![BU of 6oug by Molmil](/molmil-images/mine/6oug) | Structure of drug-resistant V27A mutant of the influenza M2 proton channel bound to spiroadamantyl amine inhibitor, TM + cytosolic helix construct | Descriptor: | (1r,1'S,3'S,5'S,7'S)-spiro[cyclohexane-1,2'-tricyclo[3.3.1.1~3,7~]decan]-4-amine, Matrix protein 2 | Authors: | Thomaston, J.L, Liu, L, DeGrado, W.F. | Deposit date: | 2019-05-04 | Release date: | 2020-01-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | X-ray Crystal Structures of the Influenza M2 Proton Channel Drug-Resistant V27A Mutant Bound to a Spiro-Adamantyl Amine Inhibitor Reveal the Mechanism of Adamantane Resistance. Biochemistry, 59, 2020
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4O3M
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![BU of 4o3m by Molmil](/molmil-images/mine/4o3m) | Ternary complex of Bloom's syndrome helicase | Descriptor: | 1,2-ETHANEDIOL, 5'-D(*AP*GP*CP*GP*TP*CP*GP*AP*GP*AP*TP*CP*CP*AP*AP*G)-3', 5'-D(*CP*TP*TP*GP*GP*AP*TP*CP*TP*CP*GP*AP*CP*GP*CP*TP*CP*TP*CP*CP*CP*TP*TP*A)-3', ... | Authors: | Swan, M.K, Bertrand, J. | Deposit date: | 2013-12-18 | Release date: | 2014-03-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA. Acta Crystallogr.,Sect.D, 70, 2014
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3FS7
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![BU of 3fs7 by Molmil](/molmil-images/mine/3fs7) | Crystal structure of Gallus gallus beta-parvalbumin (avian thymic hormone) | Descriptor: | CALCIUM ION, GLYCEROL, Parvalbumin, ... | Authors: | Schuermann, J.P, Tanner, J.J, Henzl, M.T. | Deposit date: | 2009-01-09 | Release date: | 2010-01-19 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9539 Å) | Cite: | Structure of avian thymic hormone, a high-affinity avian beta-parvalbumin, in the Ca2+-free and Ca2+-bound states. J.Mol.Biol., 397, 2010
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6K5O
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![BU of 6k5o by Molmil](/molmil-images/mine/6k5o) | Development of Novel Lithocholic Acid Derivatives as Vitamin D Receptor Agonists | Descriptor: | (4~{R})-4-[(3~{R},5~{R},8~{R},9~{S},10~{S},13~{R},14~{S},17~{R})-10,13-dimethyl-3-methylsulfonyloxy-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1~{H}-cyclopenta[a]phenanthren-17-yl]pentanoic acid, Mediator of RNA polymerase II transcription subunit 1, Vitamin D3 receptor | Authors: | Masuno, H, Kagechika, H, Ito, N. | Deposit date: | 2019-05-29 | Release date: | 2019-07-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Development of novel lithocholic acid derivatives as vitamin D receptor agonists. Bioorg.Med.Chem., 27, 2019
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6KIQ
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![BU of 6kiq by Molmil](/molmil-images/mine/6kiq) | Complex of yeast cytoplasmic dynein MTBD-High and MT with DTT | Descriptor: | Alpha tubulin, Dynein heavy chain, cytoplasmic, ... | Authors: | Komori, Y, Nishida, N, Shimada, I, Kikkawa, M. | Deposit date: | 2019-07-19 | Release date: | 2020-03-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | Structural basis for two-way communication between dynein and microtubules. Nat Commun, 11, 2020
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6KIO
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![BU of 6kio by Molmil](/molmil-images/mine/6kio) | Complex of yeast cytoplasmic dynein MTBD-High and MT without DTT | Descriptor: | Dynein heavy chain, cytoplasmic, Tubulin alpha-1A chain, ... | Authors: | Komori, Y, Nishida, N, Shimada, I, Kikkawa, M. | Deposit date: | 2019-07-19 | Release date: | 2020-03-04 | Last modified: | 2020-03-11 | Method: | ELECTRON MICROSCOPY (3.94 Å) | Cite: | Structural basis for two-way communication between dynein and microtubules. Nat Commun, 11, 2020
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4HVI
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4HVG
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![BU of 4hvg by Molmil](/molmil-images/mine/4hvg) | |
4HVH
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![BU of 4hvh by Molmil](/molmil-images/mine/4hvh) | |
4HVD
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![BU of 4hvd by Molmil](/molmil-images/mine/4hvd) | JAK3 kinase domain in complex with 2-Cyclopropyl-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-1,2,2-trimethyl-propyl)-amide | Descriptor: | 1-phenylurea, 2-cyclopropyl-N-[(2S)-3,3-dimethylbutan-2-yl]-5H-pyrrolo[2,3-b]pyrazine-7-carboxamide, Tyrosine-protein kinase JAK3 | Authors: | Kuglstatter, A, Shao, A. | Deposit date: | 2012-11-06 | Release date: | 2013-01-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | 3-Amido Pyrrolopyrazine JAK Kinase Inhibitors: Development of a JAK3 vs JAK1 Selective Inhibitor and Evaluation in Cellular and in Vivo Models. J.Med.Chem., 56, 2013
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6NV1
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![BU of 6nv1 by Molmil](/molmil-images/mine/6nv1) | Structure of drug-resistant V27A mutant of the influenza M2 proton channel bound to spiroadamantyl amine inhibitor | Descriptor: | (1r,1'S,3'S,5'S,7'S)-spiro[cyclohexane-1,2'-tricyclo[3.3.1.1~3,7~]decan]-4-amine, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, ... | Authors: | Thomaston, J.L, Liu, L, DeGrado, W.F. | Deposit date: | 2019-02-04 | Release date: | 2020-01-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | X-ray Crystal Structures of the Influenza M2 Proton Channel Drug-Resistant V27A Mutant Bound to a Spiro-Adamantyl Amine Inhibitor Reveal the Mechanism of Adamantane Resistance. Biochemistry, 59, 2020
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8DNN
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![BU of 8dnn by Molmil](/molmil-images/mine/8dnn) | Crystal structure of neutralizing antibody 80 in complex with SARS-CoV-2 receptor binding domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 80 FAB HEAVY CHAIN, 80 FAB LIGHT CHAIN, ... | Authors: | Muthuraman, K, Kucharska, I, Ivanochko, D, Julien, J.P. | Deposit date: | 2022-07-11 | Release date: | 2023-05-24 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo. Sci Transl Med, 15, 2023
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2KQY
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![BU of 2kqy by Molmil](/molmil-images/mine/2kqy) | Solution structure of Avian Thymic Hormone | Descriptor: | Parvalbumin, thymic | Authors: | Henzl, M.T. | Deposit date: | 2009-11-24 | Release date: | 2010-04-07 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Structure of Avian Thymic Hormone, a High-Affinity Avian beta-Parvalbumin, in the Ca(2+)-Free and Ca(2+)-Bound States. J.Mol.Biol., 397, 2010
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2LVJ
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![BU of 2lvj by Molmil](/molmil-images/mine/2lvj) | solution structure of hemi-Mg-bound Phl p 7 | Descriptor: | MAGNESIUM ION, Polcalcin Phl p 7 | Authors: | Henzl, M.T, Tanner, J.J. | Deposit date: | 2012-07-05 | Release date: | 2012-10-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structures of polcalcin Phl p 7 in three ligation states: Apo-, hemi-Mg(2+) -bound, and fully Ca(2+) -bound. Proteins, 81, 2013
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2LVI
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![BU of 2lvi by Molmil](/molmil-images/mine/2lvi) | Solution structure of apo-Phl p 7 | Descriptor: | Polcalcin Phl p 7 | Authors: | Henzl, M.T, Tanner, J.J. | Deposit date: | 2012-07-05 | Release date: | 2012-10-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structures of polcalcin Phl p 7 in three ligation states: Apo-, hemi-Mg(2+) -bound, and fully Ca(2+) -bound. Proteins, 81, 2013
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2LVK
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![BU of 2lvk by Molmil](/molmil-images/mine/2lvk) | Solution structure of Ca-bound Phl p 7 | Descriptor: | CALCIUM ION, Polcalcin Phl p 7 | Authors: | Henzl, M.T, Sirianni, A.G, Tanner, J.J. | Deposit date: | 2012-07-05 | Release date: | 2012-10-03 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structures of polcalcin Phl p 7 in three ligation states: Apo-, hemi-Mg(2+) -bound, and fully Ca(2+) -bound. Proteins, 81, 2013
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6KPO
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![BU of 6kpo by Molmil](/molmil-images/mine/6kpo) | Crystal Structure of endo-beta-N-acetylglucosaminidase from Cordyceps militaris D154N/E156Q mutant in complex with fucosyl-N-acetylglucosamine-Asn | Descriptor: | ASPARAGINE, Chitinase, DI(HYDROXYETHYL)ETHER, ... | Authors: | Seki, H, Arakawa, T, Yamada, C, Takegawa, K, Fushinobu, S. | Deposit date: | 2019-08-15 | Release date: | 2019-10-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Structural basis for the specific cleavage of core-fucosylatedN-glycans by endo-beta-N-acetylglucosaminidase from the fungusCordyceps militaris. J.Biol.Chem., 294, 2019
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6KPN
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![BU of 6kpn by Molmil](/molmil-images/mine/6kpn) | Crystal Structure of endo-beta-N-acetylglucosaminidase from Cordyceps militaris D154N/E156Q mutant in complex with fucosyl-N-acetylglucosamine | Descriptor: | Chitinase, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Seki, H, Arakawa, T, Yamada, C, Takegawa, K, Fushinobu, S. | Deposit date: | 2019-08-15 | Release date: | 2019-10-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for the specific cleavage of core-fucosylatedN-glycans by endo-beta-N-acetylglucosaminidase from the fungusCordyceps militaris. J.Biol.Chem., 294, 2019
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