3NXS
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7VM0
| Crystal structure of YojK from B.subtilis in complex with UDP | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Glycosyl transferase family 1, ... | Authors: | Hou, X.D, Guo, B.D, Rao, Y.J. | Deposit date: | 2021-10-06 | Release date: | 2022-10-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Highly efficient production of rebaudioside D enabled by structure-guided engineering of bacterial glycosyltransferase YojK. Front Bioeng Biotechnol, 10, 2022
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3OEC
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7W3Y
| CryoEM structure of human Kv4.3 | Descriptor: | Isoform 2 of Potassium voltage-gated channel subfamily D member 3 | Authors: | Ma, D.M, Guo, J.T. | Deposit date: | 2021-11-26 | Release date: | 2022-11-02 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis for the gating modulation of Kv4.3 by auxiliary subunits. Cell Res., 32, 2022
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7W6S
| CryoEM structure of human KChIP2-Kv4.3 complex | Descriptor: | Isoform 2 of Potassium voltage-gated channel subfamily D member 3, Kv channel-interacting protein 2 | Authors: | Ma, D.M, Guo, J.T. | Deposit date: | 2021-12-02 | Release date: | 2022-11-02 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis for the gating modulation of Kv4.3 by auxiliary subunits. Cell Res., 32, 2022
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7W6N
| CryoEM structure of human KChIP1-Kv4.3 complex | Descriptor: | Isoform 2 of Potassium voltage-gated channel subfamily D member 3, Kv channel-interacting protein 1 | Authors: | Ma, D.M, Guo, J.T. | Deposit date: | 2021-12-02 | Release date: | 2022-11-02 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for the gating modulation of Kv4.3 by auxiliary subunits. Cell Res., 32, 2022
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7W6T
| CryoEM structure of human KChIP1-Kv4.3-DPP6 complex | Descriptor: | Dipeptidyl aminopeptidase-like protein 6, Isoform 2 of Potassium voltage-gated channel subfamily D member 3, Kv channel-interacting protein 1 | Authors: | Ma, D.M, Guo, J.T. | Deposit date: | 2021-12-02 | Release date: | 2022-11-02 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | Structural basis for the gating modulation of Kv4.3 by auxiliary subunits. Cell Res., 32, 2022
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7W8S
| Structure of SARS-CoV-2 spike receptor-binding domain Y453F mutation complexed with American mink ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1, ... | Authors: | Su, C, Qi, J.X, Gao, G.F. | Deposit date: | 2021-12-08 | Release date: | 2022-08-17 | Last modified: | 2023-04-12 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Molecular Basis of Mink ACE2 Binding to SARS-CoV-2 and Its Mink-Derived Variants. J.Virol., 96, 2022
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7WA1
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5TOE
| Pim-1 kinase in complex with a 7-azaindole | Descriptor: | 2-[4-(piperazin-1-yl)phenyl]-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile, Serine/threonine-protein kinase pim-1 | Authors: | Mclean, L, Mechin, I, Zhang, Y, Wang, R, Batchelor, J.D. | Deposit date: | 2016-10-17 | Release date: | 2017-10-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.301 Å) | Cite: | Discovery of N-substituted 7-azaindoles as PIM1 kinase inhibitors - Part I. Bioorg. Med. Chem. Lett., 27, 2017
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3OIB
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3MD0
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3NJB
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3P96
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3MTL
| Crystal structure of the PCTAIRE1 kinase in complex with Indirubin E804 | Descriptor: | (2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME}, Cell division protein kinase 16 | Authors: | Krojer, T, Sharpe, T.D, Roos, A, Savitsky, P, Amos, A, Ayinampudi, V, Berridge, G, Fedorov, O, Keates, T, Phillips, C, Burgess-Brown, N, Zhang, Y, Pike, A.C.W, Muniz, J, Vollmar, M, Thangaratnarajah, C, Rellos, P, Ugochukwu, E, Filippakopoulos, P, Yue, W, Das, S, von Delft, F, Edwards, A, Arrowsmith, C.H, Weigelt, J, Bountra, C, Knapp, S, Bullock, A, Structural Genomics Consortium (SGC) | Deposit date: | 2010-04-30 | Release date: | 2010-06-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16. Biochem.J., 474, 2017
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7VNI
| AHR-ARNT PAS-B heterodimer | Descriptor: | Ahr homolog spineless, Aryl hydrocarbon receptor nuclear translocator, SULFATE ION | Authors: | Dai, S.Y. | Deposit date: | 2021-10-11 | Release date: | 2022-04-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | Structural insight into the ligand binding mechanism of aryl hydrocarbon receptor. Nat Commun, 13, 2022
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7VNA
| drosophlia AHR PAS-B domain | Descriptor: | Ahr homolog spineless | Authors: | Dai, S.Y. | Deposit date: | 2021-10-10 | Release date: | 2022-04-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.597 Å) | Cite: | Structural insight into the ligand binding mechanism of aryl hydrocarbon receptor. Nat Commun, 13, 2022
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7VNH
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3OL3
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3OL4
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3PGX
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3P3A
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3HZU
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5TUR
| Pim-1 kinase in complex with a 7-azaindole | Descriptor: | 1-methyl-2-[4-(piperazin-1-yl)phenyl]-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile, Serine/threonine-protein kinase pim-1 | Authors: | Mechin, I, Zhang, Y, Wang, R, Batchelor, J.D, Mclean, L. | Deposit date: | 2016-11-07 | Release date: | 2017-10-11 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.948 Å) | Cite: | Discovery of N-substituted 7-azaindoles as PIM1 kinase inhibitors - Part I. Bioorg. Med. Chem. Lett., 27, 2017
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7XNK
| human KCNQ1-CaM in complex with ML277 | Descriptor: | (2R)-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-1-(4-methylbenzene-1-sulfonyl)piperidine-2-carboxamide, Calmodulin-3, POTASSIUM ION, ... | Authors: | Ma, D, Guo, J. | Deposit date: | 2022-04-29 | Release date: | 2022-12-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers. Proc.Natl.Acad.Sci.USA, 119, 2022
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