6OEA
| Crystal structure of HMCES SRAP domain in complex with longer 3' overhang DNA | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*CP*CP*AP*GP*AP*CP*GP*TP*TP*GP*TP*T)-3'), DNA (5'-D(*GP*TP*CP*TP*GP*G)-3'), ... | Authors: | Halabelian, L, Ravichandran, M, Li, Y, Zeng, H, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | Deposit date: | 2019-03-27 | Release date: | 2019-04-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition. Nat.Struct.Mol.Biol., 26, 2019
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6QD5
| X-ray Structure of the Human Urea Channel SLC14A1/UT1 | Descriptor: | CHOLESTEROL HEMISUCCINATE, TETRAETHYLENE GLYCOL, Urea transporter 1, ... | Authors: | Dietz, L, Chi, G, Pike, A.C.W, Moreau, C, Man, H, Snee, M, Scacioc, A, Shrestha, L, Mukhopadhyay, S.M.M, Mckinley, G, Ellis, K, Kliszcak, M, Chalk, R, Borkowska, O, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Durr, K.L, Structural Genomics Consortium (SGC) | Deposit date: | 2018-12-31 | Release date: | 2019-01-09 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.398 Å) | Cite: | X-ray Structure of the Human Urea Channel SLC14A1/UT1 To Be Published
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6QU2
| Crystal structure of DYRK1A complexed with FC162 inhibitor | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-cyclopropyl-2-pyridin-3-yl-[1,3]thiazolo[5,4-f]quinazolin-9-one, DIMETHYL SULFOXIDE, ... | Authors: | Chaikuad, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Besson, T, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2019-02-26 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of DYRK1A complexed with FC162 inhibitor To Be Published
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6OQM
| crystal structure of the MSH6 PWWP domain | Descriptor: | DNA mismatch repair protein Msh6, MAGNESIUM ION, SULFATE ION, ... | Authors: | Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium, Structural Genomics Consortium (SGC) | Deposit date: | 2019-04-26 | Release date: | 2019-05-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | crystal structure of the MSH6 PWWP domain To Be Published
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6QZL
| Structure of the H1 domain of human KCTD12 | Descriptor: | BTB/POZ domain-containing protein KCTD12 | Authors: | Pinkas, D.M, Bufton, J.C, Fox, A.E, Newman, J.A, Kupinska, K, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N, Structural Genomics Consortium (SGC) | Deposit date: | 2019-03-11 | Release date: | 2019-03-20 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structure of the H1 domain of human KCTD12 To be published
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6QNV
| Fibrinogen-like globe domain of Human Tenascin-C | Descriptor: | Tenascin | Authors: | Coker, J.A, Bezerra, G.A, Bradshaw, W.J, Zhang, M, Yosaatmadja, Y, Fernandez-Cid, A, Shrestha, L, Burgess-Brown, N, Gileadi, O, Arrowsmith, C.H, Bountra, C, Midwood, K.S, Yue, W.W, Marsden, B.D, Structural Genomics Consortium (SGC) | Deposit date: | 2019-02-12 | Release date: | 2019-02-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Fibrinogen-like globe domain of Human Tenascin-C To Be Published
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6QPL
| Crystal structure of Spindlin1 in complex with the inhibitor MS31 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Johansson, C, Krojer, T, Xiong, Y, Jin, J, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.C.T. | Deposit date: | 2019-02-14 | Release date: | 2019-07-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1). J.Med.Chem., 62, 2019
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1HYW
| SOLUTION STRUCTURE OF BACTERIOPHAGE LAMBDA GPW | Descriptor: | HEAD-TO-TAIL JOINING PROTEIN W | Authors: | Maxwell, K.L, Yee, A.A, Booth, V, Arrowsmith, C.H, Gold, M, Davidson, A.R. | Deposit date: | 2001-01-22 | Release date: | 2001-04-25 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The solution structure of bacteriophage lambda protein W, a small morphogenetic protein possessing a novel fold. J.Mol.Biol., 308, 2001
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1IIO
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1K0H
| Solution structure of bacteriophage lambda gpFII | Descriptor: | gpFII | Authors: | Maxwell, K.L, Yee, A.A, Arrowsmith, C.H, Gold, M, Davidson, A.R. | Deposit date: | 2001-09-19 | Release date: | 2002-07-17 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The solution structure of the bacteriophage lambda head-tail joining protein, gpFII. J.Mol.Biol., 318, 2002
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1K3R
| Crystal Structure of the Methyltransferase with a Knot from Methanobacterium thermoautotrophicum | Descriptor: | conserved protein MT0001 | Authors: | Zarembinski, T.I, Kim, Y, Peterson, K, Christendat, D, Dharamsi, A, Arrowsmith, C.H, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2001-10-03 | Release date: | 2002-05-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Deep trefoil knot implicated in RNA binding found in an archaebacterial protein. Proteins, 50, 2003
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1K77
| Crystal Structure of EC1530, a Putative Oxygenase from Escherichia coli | Descriptor: | FORMIC ACID, GLYCEROL, Hypothetical protein ygbM, ... | Authors: | Kim, Y, Skarina, T, Beasley, S, Laskowski, R, Arrowsmith, C.H, Joachimiak, A, Edwards, A.M, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2001-10-18 | Release date: | 2002-03-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Crystal structure of Escherichia coli EC1530, a glyoxylate induced protein YgbM. Proteins, 48, 2002
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1L1S
| Structure of Protein of Unknown Function MTH1491 from Methanobacterium thermoautotrophicum | Descriptor: | hypothetical protein MTH1491 | Authors: | Christendat, D, Saridakis, V, Kim, Y, Kumar, P.A, Xu, X, Semesi, A, Joachimiak, A, Arrowsmith, C.H, Edwards, A.M, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2002-02-19 | Release date: | 2002-05-29 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structure of hypothetical protein MTH1491 from Methanobacterium thermoautotrophicum. Protein Sci., 11, 2002
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1LKN
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1LFC
| BOVINE LACTOFERRICIN (LFCINB), NMR, 20 STRUCTURES | Descriptor: | LACTOFERRICIN | Authors: | Hwang, P.M, Zhou, N, Shan, X, Arrowsmith, C.H, Vogel, H.J. | Deposit date: | 1998-06-24 | Release date: | 1998-11-04 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Three-dimensional solution structure of lactoferricin B, an antimicrobial peptide derived from bovine lactoferrin. Biochemistry, 37, 1998
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1LXJ
| X-RAY STRUCTURE OF YBL001c NORTHEAST STRUCTURAL GENOMICS (NESG) CONSORTIUM TARGET YTYst72 | Descriptor: | HYPOTHETICAL 11.5KDA PROTEIN IN HTB2-NTH2 INTERGENIC REGION, SULFATE ION | Authors: | Tao, X, Khayat, R, Christendat, D, Savchenko, A, Xu, X, Edwards, A, Arrowsmith, C.H, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2002-06-05 | Release date: | 2003-07-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | CRYSTAL STRUCTURES OF MTH1187 AND ITS YEAST ORTHOLOG YBL001C Proteins, 52, 2003
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1LXN
| X-RAY STRUCTURE OF MTH1187 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT272 | Descriptor: | HYPOTHETICAL PROTEIN MTH1187, SULFATE ION | Authors: | Tao, X, Khayat, R, Christendat, D, Savchenko, A, Xu, X, Edwards, A, Arrowsmith, C.H, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2002-06-05 | Release date: | 2003-07-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structures of MTH1187 and its Yeast Ortholog YBL001C Proteins, 52, 2003
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1KUU
| CRYSTAL STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM CONSERVED PROTEIN MTH1020 REVEALS AN NTN-HYDROLASE FOLD | Descriptor: | conserved protein | Authors: | Saridakis, V, Christendat, D, Thygesen, A, Arrowsmith, C.H, Edwards, A.M, Pai, E.F. | Deposit date: | 2002-01-22 | Release date: | 2002-05-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | CRYSTAL STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM CONSERVED PROTEIN MTH1020 REVEALS AN NTN-HYDROLASE FOLD PROTEINS: STRUCT.,FUNCT.,GENET., 48, 2002
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1M94
| Solution Structure of the Yeast Ubiquitin-Like Modifier Protein Hub1 | Descriptor: | Protein YNR032c-a | Authors: | Ramelot, T.A, Cort, J.R, Yee, A.A, Semesi, A, Edwards, A.M, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2002-07-26 | Release date: | 2002-12-11 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution Structure of the Yeast Ubiquitin-Like Modifier Protein Hub1 J.STRUCT.FUNCT.GENOM., 4, 2003
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1MP1
| Solution structure of the PWI motif from SRm160 | Descriptor: | Ser/Arg-related nuclear matrix protein | Authors: | Szymczyna, B.R, Bowman, J, McCracken, S, Pineda-Lucena, A, Lu, Y, Cox, B, Lambermon, M, Graveley, B.R, Arrowsmith, C.H, Blencowe, B.J. | Deposit date: | 2002-09-11 | Release date: | 2003-09-16 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure and function of the PWI motif: a novel nucleic acid-binding domain that facilitates pre-mRNA processing. Genes Dev., 17, 2003
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6Y41
| Fibrinogen-like globe domain of human ANGPTL2 | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Angiopoietin-related protein 2, ... | Authors: | Coker, J.A, Krojer, T, Mutisya, J.M, Arrowsmith, C.H, Bountra, C, Midwood, K.S, Yue, W.W, Marsden, B.D, Structural Genomics Consortium (SGC) | Deposit date: | 2020-02-19 | Release date: | 2020-03-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Fibrinogen-like globe domain of human ANGPTL2 To Be Published
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6Y7F
| Crystal structure of human ELOVL fatty acid elongase 7 (ELOVL7) | Descriptor: | CHLORIDE ION, Elongation of very long chain fatty acids protein 7, Octyl Glucose Neopentyl Glycol, ... | Authors: | Nie, L, Pike, A.C.W, Bushell, S.R, Chu, A, Cole, V, Speedman, D, Rodstrom, K.E.J, Kupinska, K, Shrestha, L, Mukhopadhyay, S.M.M, Burgess-Brown, N.A, Love, J, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | Deposit date: | 2020-02-28 | Release date: | 2020-05-13 | Method: | X-RAY DIFFRACTION (2.052 Å) | Cite: | Crystal structure of human ELOVL fatty acid elongase 7 (ELOVL7) TO BE PUBLISHED
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6Y43
| Fibrinogen-like globe domain of human ANGPTL6 | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Angiopoietin-related protein 6, ... | Authors: | Coker, J.A, Krojer, T, Mutisya, J.M, Arrowsmith, C.H, Bountra, C, Midwood, K.S, Yue, W.W, Marsden, B.D, Structural Genomics Consortium (SGC) | Deposit date: | 2020-02-19 | Release date: | 2020-03-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Fibrinogen-like globe domain of human ANGPTL6 To Be Published
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6YIM
| Crystal structure of the CREBBP bromodomain in complex with a benzo-diazepine ligand | Descriptor: | (4~{R})-~{N}-[3-(7-methoxy-3,4-dihydro-2~{H}-quinolin-1-yl)propyl]-4-methyl-2-oxidanylidene-1,3,4,5-tetrahydro-1,5-benzodiazepine-6-carboxamide, CREBBP | Authors: | Picaud, S, Brand, M, Tobias, K, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Conway, S, Filippakopoulos, P. | Deposit date: | 2020-04-01 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.23 Å) | Cite: | Crystal structure of the CREBBP bromodomain in complex with a benzo-diazepine ligand To Be Published
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6Y5R
| Structure of Human Potassium Chloride Transporter KCC3 S45D/T940D/T997D in NaCl | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 12 member 6, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Chi, G, Man, H, Ebenhoch, R, Reggiano, G, Pike, A.C.W, Wang, D, McKinley, G, Mukhopadhyay, S.M.M, MacLean, B, Chalk, R, Moreau, C, Snee, M, Bohstedt, T, Singh, N.K, Abrusci, P, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Marsden, B.D, Burgess-Brown, N.A, DiMaio, F, Duerr, K.L, Structural Genomics Consortium (SGC) | Deposit date: | 2020-02-25 | Release date: | 2020-03-11 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.76 Å) | Cite: | Structure of Human Potassium Chloride Transporter KCC3 in NaCl To be published
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