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The crystal structure of human VISTA extra cellular domain in complex with Fab fragment of pH-selective anti-VISTA antibody
分子名称:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, SNS-101 Fab heavy chain, ...
著者	van der Horst, E.H, Mukherjee, A, Thisted, T.
登録日	2023-06-29
公開日	2024-03-20
実験手法	X-RAY DIFFRACTION (2.593 Å)
主引用文献	The pH-selective anti-VISTA antibody SNS-101 displays a favorable pharmacokinetic and safety profile and promotes anti-tumoral M1 macrophage polarization in PD-1 refractory settings To Be Published

BRD4(BD1) complexed with 2759
分子名称:	1,2-ETHANEDIOL, 1-benzyl-5-(3,5-dimethyl-1,2-oxazol-4-yl)pyridin-2(1H)-one, Bromodomain-containing protein 4
著者	Lakshminarasimhan, D, White, A, Suto, R.K.
登録日	2018-04-09
公開日	2018-09-26
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (1.88 Å)
主引用文献	Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine. J. Med. Chem., 61, 2018

BRD4(BD1) complexed with 3219
分子名称:	1,2-ETHANEDIOL, 5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-({4-[(1R)-1-hydroxyethyl]phenyl}methyl)pyridin-2(1H)-one, Bromodomain-containing protein 4, ...
著者	Lakshminarasimhan, D, White, A, Suto, R.K.
登録日	2018-04-09
公開日	2018-09-26
最終更新日	2018-10-10
実験手法	X-RAY DIFFRACTION (1.47 Å)
主引用文献	Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine. J. Med. Chem., 61, 2018