Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
7WH7
DownloadVisualize
BU of 7wh7 by Molmil
The mutant crystal structure of b-1,4-Xylanase (XynAF1_N179S) with xylotetraose
分子名称: Beta-xylanase, alpha-D-mannopyranose-(1-2)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Li, G.Q, Zhang, R.F.
登録日2021-12-30
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献The mutant crystal structure of b-1,4-Xylanase (XynAF1_N179S) with xylotetraose
To Be Published
7WHA
DownloadVisualize
BU of 7wha by Molmil
The mutant crystal structure of b-1,4-Xylanase (XynAF1_R246K)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-xylanase, GLYCEROL
著者Li, G.Q, Zhang, R.F.
登録日2021-12-30
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献The mutant crystal structure of b-1,4-Xylanase (XynAF1_R246K)
To Be Published
7WHE
DownloadVisualize
BU of 7whe by Molmil
The mutant crystal structure of b-1,4-Xylanase (XynAF1_R246K) with xylobiose
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-xylanase, GLYCEROL, ...
著者Li, G.Q, Zhang, R.F.
登録日2021-12-30
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The mutant crystal structure of b-1,4-Xylanase (XynAF1_R246K) with xylobiose
To Be Published
7WH6
DownloadVisualize
BU of 7wh6 by Molmil
The mutant crystal structure of b-1,4-Xylanase (XynAF1_N179S)
分子名称: Beta-xylanase, GLYCEROL, alpha-D-mannopyranose-(1-2)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Li, G.Q, Zhang, R.F.
登録日2021-12-30
公開日2023-01-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献The mutant crystal structure of b-1,4-Xylanase (XynAF1_N179S)
To Be Published
3MVM
DownloadVisualize
BU of 3mvm by Molmil
P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7V
分子名称: 4-{[5-(isoxazol-3-ylcarbamoyl)-2-methylphenyl]amino}-5-methyl-N-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide, Mitogen-activated protein kinase 14
著者Sack, J.S.
登録日2010-05-04
公開日2010-10-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of 4-(5-(Cyclopropylcarbamoyl)-2-Methylphenylamino)-5-Methyl-Npropylpyrrolo[1,2-F][1,2,4] Triazine-6-Carboxamide (Bms-582949), a Clinical P38? Map Kinase Inhibitor for the Treatment of Inflammatory Diseases
J.Med.Chem., 53, 2010
3MVL
DownloadVisualize
BU of 3mvl by Molmil
P38 Alpha Map Kinase complexed with pyrrolotriazine inhibitor 7K
分子名称: 4-{[5-(cyclopropylcarbamoyl)-2-methylphenyl]amino}-5-methyl-N-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxamide, Mitogen-activated protein kinase 14
著者Sack, J.S.
登録日2010-05-04
公開日2010-10-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Discovery of 4-(5-(Cyclopropylcarbamoyl)-2-Methylphenylamino)-5-Methyl-Npropylpyrrolo[1,2-F][1,2,4] Triazine-6-Carboxamide (Bms-582949), a Clinical P38 Map Kinase Inhibitor for the Treatment of Inflammatory Diseases
J.Med.Chem., 53, 2010
4RIO
DownloadVisualize
BU of 4rio by Molmil
Crystal structure of JAK3 kinase domain in complex with a pyrrolopyridazine carboxamide inhibitor
分子名称: 4-{[(1R,2S)-2-fluoro-2-methylcyclopentyl]amino}pyrrolo[1,2-b]pyridazine-3-carboxamide, Tyrosine-protein kinase JAK3
著者Sack, J.S.
登録日2014-10-07
公開日2014-12-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Discovery of pyrrolo[1,2-b]pyridazine-3-carboxamides as Janus kinase (JAK) inhibitors.
Bioorg.Med.Chem.Lett., 24, 2014
3C5U
DownloadVisualize
BU of 3c5u by Molmil
P38 ALPHA map kinase complexed with a benzothiazole based inhibitor
分子名称: 6-[4-(2-fluorophenyl)-1,3-oxazol-5-yl]-N-(1-methylethyl)-1,3-benzothiazol-2-amine, Mitogen-activated protein kinase 14
著者Sack, J.S.
登録日2008-02-01
公開日2008-03-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Benzothiazole based inhibitors of p38alpha MAP kinase.
Bioorg.Med.Chem.Lett., 18, 2008
6NY4
DownloadVisualize
BU of 6ny4 by Molmil
Crystal structure of JAK3 kinase domain in complex with a pyrrolopyridazine carboxamide inhibitor
分子名称: 4-{[(2R,3R)-1,3-dihydroxybutan-2-yl]amino}-6-phenylpyrrolo[1,2-b]pyridazine-3-carboxamide, Tyrosine-protein kinase JAK3
著者Sack, J.S.
登録日2019-02-11
公開日2019-05-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis.
Acs Med.Chem.Lett., 10, 2019
7W0W
DownloadVisualize
BU of 7w0w by Molmil
The novel membrane-proximal sensing mechanism in a broad-ligand binding chemoreceptor McpA of Bacillus velezensis
分子名称: (2S)-2-hydroxybutanedioic acid, 1,2-ETHANEDIOL, ACETATE ION, ...
著者Feng, H.C, Shen, Q.R, Zhang, R.F.
登録日2021-11-18
公開日2022-07-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.247 Å)
主引用文献Signal binding at both modules of its dCache domain enables the McpA chemoreceptor of Bacillus velezensis to sense different ligands.
Proc.Natl.Acad.Sci.USA, 119, 2022
5VO6
DownloadVisualize
BU of 5vo6 by Molmil
CRYSTAL STRUCTURE OF JAK3 KINASE DOMAIN IN COMPLEX WITH A PYRROLOPYRIDAZINE INHIBITOR
分子名称: 4-{[(1R,3S)-3-amino-2,2,3-trimethylcyclopentyl]amino}-6-phenylpyrrolo[1,2-b]pyridazine-3-carboxamide, Tyrosine-protein kinase JAK3
著者Sack, J.S.
登録日2017-05-02
公開日2017-05-31
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Discovery of potent and efficacious pyrrolopyridazines as dual JAK1/3 inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017

224201

件を2024-08-28に公開中

PDB statisticsPDBj update infoContact PDBjnumon