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8HZR
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BU of 8hzr by Molmil
Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with PF07321332
分子名称: (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase nsp5
著者Zeng, X.Y, Zhang, J, Li, J.
登録日2023-01-09
公開日2024-01-17
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with PF07321332
To Be Published
8HVV
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BU of 8hvv by Molmil
Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with PF07304814
分子名称: 3C-like proteinase nsp5, [(3~{S})-3-[[(2~{S})-2-[(4-methoxy-1~{H}-indol-2-yl)carbonylamino]-4-methyl-pentanoyl]amino]-2-oxidanylidene-4-[(3~{R})-2-oxidanylidene-3,4-dihydropyrrol-3-yl]butyl] dihydrogen phosphate
著者Zeng, X.Y, Zhang, J, Li, J.
登録日2022-12-28
公開日2024-01-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structures of main protease (M pro ) mutants of SARS-CoV-2 variants bound to PF-07304814.
Mol Biomed, 4, 2023
8IG8
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BU of 8ig8 by Molmil
Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with GC376
分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Zeng, X.Y, Zhang, J, Li, J.
登録日2023-02-20
公開日2024-03-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376.
J.Mol.Biol., 436, 2024
8HUU
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BU of 8huu by Molmil
Crystal structure of HCoV-NL63 main protease with S217622
分子名称: 3C-like proteinase, 6-[(6-chloranyl-2-methyl-indazol-5-yl)amino]-3-[(1-methyl-1,2,4-triazol-3-yl)methyl]-1-[[2,4,5-tris(fluoranyl)phenyl]methyl]-1,3,5-triazine-2,4-dione
著者Zeng, X.Y, Zhang, J, Li, J.
登録日2022-12-24
公開日2023-06-21
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Structural basis for the inhibition of coronaviral main proteases by ensitrelvir.
Structure, 31, 2023
7XT0
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BU of 7xt0 by Molmil
Crystal structure of RNA helicase from Saint Louis encephalitis virus and discovery of its inhibitors
分子名称: 1,2-ETHANEDIOL, RNA helicase
著者Wang, D.P, Jiang, F.Y, Zeng, X.Y, Zhao, R, Chen, C, Zhu, Y, Cao, J.M.
登録日2022-05-15
公開日2023-11-01
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Crystal structure of RNA helicase from Saint Louis encephalitis virus and discovery of its inhibitors
To Be Published

223790

件を2024-08-14に公開中

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