8IFJ
 
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3VQV
 | | Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with AMPPNP (re-refined) | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Pyrrolysine--tRNA ligase | | 著者 | Yanagisawa, T, Sumida, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2012-04-01 | | 公開日 | 2013-01-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site
Acta Crystallogr.,Sect.D, 69, 2013
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8YFE
 | | Cryo EM structure of Komagataella phaffii Rat1-Rai1 complex | | 分子名称: | 5'-3' exoribonuclease, Decapping nuclease | | 著者 | Yanagisawa, T, Murayama, Y, Ehara, H, Sekine, S.I. | | 登録日 | 2024-02-24 | | 公開日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex.
Nat Commun, 15, 2024
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8YF5
 | | Cryo EM structure of Komagataella phaffii Rat1-Rai1-Rtt103 complex | | 分子名称: | 5'-3' exoribonuclease, Decapping nuclease, Exonuclease Rat1p and Rai1p interacting protein | | 著者 | Yanagisawa, T, Murayama, Y, Ehara, H, Sekine, S.I. | | 登録日 | 2024-02-24 | | 公開日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | | 主引用文献 | Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex.
Nat Commun, 15, 2024
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2E3C
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2EL7
 | | Crystal structure of Tryptophanyl-tRNA synthetase from Thermus thermophilus | | 分子名称: | PHOSPHATE ION, Tryptophanyl-tRNA synthetase | | 著者 | Yanagisawa, T, Sumida, T, Ishii, R, Sekine, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-26 | | 公開日 | 2008-03-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of Tryptophanyl-tRNA synthetase from Thermus thermophilus
To be published
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2EL9
 | | Crystal structure of E.coli Histidyl-tRNA synthetase complexed with a histidyl-adenylate analogue | | 分子名称: | 5'-O-[(L-HISTIDYLAMINO)SULFONYL]ADENOSINE, Histidyl-tRNA synthetase | | 著者 | Yanagisawa, T, Si, S.Y, Matsuno, M, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-03-27 | | 公開日 | 2008-03-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of E.coli Histidyl-tRNA synthetase complexed with a histidyl-adenylate analogue
To be published
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2ZIN
 | | Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with BocLys and an ATP analogue | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, N~6~-(tert-butoxycarbonyl)-L-lysine, ... | | 著者 | Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2008-02-19 | | 公開日 | 2008-12-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Multistep Engineering of Pyrrolysyl-tRNA Synthetase to Genetically Encode N(varepsilon)-(o-Azidobenzyloxycarbonyl) lysine for Site-Specific Protein Modification
Chem.Biol., 15, 2008
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2ZCE
 | | Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with pyrrolysine and an ATP analogue | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PYRROLYSINE, ... | | 著者 | Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-11-08 | | 公開日 | 2008-04-22 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystallographic Studies on Multiple Conformational States of Active-site Loops in Pyrrolysyl-tRNA Synthetase
J.Mol.Biol., 378, 2008
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3VQW
 | | Crystal structure of the SeMet substituted catalytic domain of pyrrolysyl-tRNA synthetase | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Pyrrolysine--tRNA ligase | | 著者 | Yanagisawa, T, Sumida, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2012-04-01 | | 公開日 | 2013-01-02 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site
Acta Crystallogr.,Sect.D, 69, 2013
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3VQY
 | | Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with BocLys and AMPPNP (form 2) | | 分子名称: | MAGNESIUM ION, N~6~-(tert-butoxycarbonyl)-L-lysine, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Yanagisawa, T, Sumida, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2012-04-02 | | 公開日 | 2013-01-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site
Acta Crystallogr.,Sect.D, 69, 2013
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2ZIO
 | | Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in complex with AlocLys-AMP and PNP | | 分子名称: | 5'-O-[(S)-({(2S)-2-amino-6-[(propoxycarbonyl)amino]hexanoyl}oxy)(hydroxy)phosphoryl]adenosine, IMIDODIPHOSPHORIC ACID, Pyrrolysyl-tRNA synthetase | | 著者 | Yanagisawa, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2008-02-19 | | 公開日 | 2008-12-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Multistep Engineering of Pyrrolysyl-tRNA Synthetase to Genetically Encode N(varepsilon)-(o-Azidobenzyloxycarbonyl) lysine for Site-Specific Protein Modification
Chem.Biol., 15, 2008
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3VQX
 | | Crystal structure of the catalytic domain of pyrrolysyl-tRNA synthetase in triclinic crystal form | | 分子名称: | ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, Pyrrolysine--tRNA ligase, ... | | 著者 | Yanagisawa, T, Sumida, T, Ishii, R, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2012-04-02 | | 公開日 | 2013-01-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site
Acta Crystallogr.,Sect.D, 69, 2013
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3WNC
 | | Crystal structure of EF-Pyl in complex with GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein translation elongation factor 1A | | 著者 | Yanagisawa, T, Ishii, R, Fukunaga, R, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2013-12-08 | | 公開日 | 2014-12-10 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A SelB/EF-Tu/aIF2 gamma-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.).
J. Struct. Funct. Genomics, 16, 2015
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3WNB
 | | Crystal structure of EF-Pyl in complex with GMPPNP | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein translation elongation factor 1A | | 著者 | Yanagisawa, T, Ishii, R, Fukunaga, R, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2013-12-08 | | 公開日 | 2014-12-10 | | 最終更新日 | 2020-05-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A SelB/EF-Tu/aIF2 gamma-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.).
J. Struct. Funct. Genomics, 16, 2015
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3WND
 | | Crystal structure of EF-Pyl | | 分子名称: | CITRIC ACID, Protein translation elongation factor 1A | | 著者 | Yanagisawa, T, Ishii, R, Fukunaga, R, Sengoku, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2013-12-08 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | A SelB/EF-Tu/aIF2 gamma-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNA(Cys.).
J. Struct. Funct. Genomics, 16, 2015
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6ABK
 | | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with TeocLys | | 分子名称: | (2S)-2-azanyl-6-(trimethylsilylmethoxycarbonylamino)hexanoic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Yanagisawa, T, Kuratani, M, Yokoyama, S. | | 登録日 | 2018-07-22 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
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6AAP
 | | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with ZaeSeCys | | 分子名称: | 3-[(2-{[(benzyloxy)carbonyl]amino}ethyl)selanyl]-L-alanine, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Yanagisawa, T, Kuratani, M, Yokoyama, S. | | 登録日 | 2018-07-18 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
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6AAO
 | | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with TCO*Lys | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | | 著者 | Yanagisawa, T, Kuratani, M, Yokoyama, S. | | 登録日 | 2018-07-18 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.403 Å) | | 主引用文献 | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
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6AB0
 | | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with pAmPyLys | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, N6-{[(6-aminopyridin-3-yl)methoxy]carbonyl}-L-lysine, ... | | 著者 | Yanagisawa, T, Kuratani, M, Yokoyama, S. | | 登録日 | 2018-07-19 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.441 Å) | | 主引用文献 | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
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6AAC
 | | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with mAzZLys | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | | 著者 | Yanagisawa, T, Kuratani, M, Yokoyama, S. | | 登録日 | 2018-07-18 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.479 Å) | | 主引用文献 | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
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6AB1
 | | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with oAzZLys | | 分子名称: | (2S)-2-azanyl-6-[(2-azidophenyl)methoxycarbonylamino]hexanoic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Yanagisawa, T, Kuratani, M, Yokoyama, S. | | 登録日 | 2018-07-19 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.381 Å) | | 主引用文献 | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
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6ABL
 | | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with oBrZLys | | 分子名称: | (2S)-2-azanyl-6-[(2-bromophenyl)methoxycarbonylamino]hexanoic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Yanagisawa, T, Kuratani, M, Yokoyama, S. | | 登録日 | 2018-07-22 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
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6AAN
 | | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with mEtZLys | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | | 著者 | Yanagisawa, T, Kuratani, M, Yokoyama, S. | | 登録日 | 2018-07-18 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
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6ABM
 | | Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with pTmdZLys | | 分子名称: | (2S)-2-azanyl-6-[[4-[3-(trifluoromethyl)-1,2-diazirin-3-yl]phenyl]methoxycarbonylamino]hexanoic acid, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Yanagisawa, T, Kuratani, M, Yokoyama, S. | | 登録日 | 2018-07-22 | | 公開日 | 2019-04-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.368 Å) | | 主引用文献 | Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
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