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Allosteric Inhibition as a new mode of Action for BAY 1213790, a Neutralizing Antibody Targeting the Activated form of Coagulation Factor XI
分子名称:	Coagulation factor XI, DIMETHYL SULFOXIDE, FXIA ANTIBODY FAB HEAVY CHAIN, ...
著者	Schaefer, M, Buchmueller, A, Dittmer, F, Strassburger, J, Wilmen, A.
登録日	2018-08-27
公開日	2019-09-11
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	Allosteric Inhibition as a New Mode of Action for BAY 1213790, a Neutralizing Antibody Targeting the Activated Form of Coagulation Factor XI. J.Mol.Biol., 431, 2019

X-ray structure of KH1-2 domain of IMP3
分子名称:	Insulin-like growth factor 2 mRNA-binding protein 3
著者	Janowski, R, Schlundt, A, Sattler, M, Niessing, D.
登録日	2018-06-07
公開日	2019-04-24
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2.15 Å)
主引用文献	Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3. Nat Commun, 10, 2019

hAPC-h1573 Fab complex
分子名称:	Vitamin K-dependent protein C heavy chain, Vitamin K-dependent protein C light chain, h1573 Fab H chain, ...
著者	Wang, X, Wang, D, Zhao, X, Egner, U.
登録日	2020-03-03
公開日	2020-07-08
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (3.7 Å)
主引用文献	Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia. Nat Commun, 11, 2020

hAPC-c25k23 Fab complex
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Vitamin K-dependent protein C heavy chain, Vitamin K-dependent protein C light chain, ...
著者	Wang, X, Li, L, Zhao, X, Egner, U.
登録日	2020-03-03
公開日	2020-07-08
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Targeted inhibition of activated protein C by a non-active-site inhibitory antibody to treat hemophilia. Nat Commun, 11, 2020