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7QVM
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BU of 7qvm by Molmil
Human Oxytocin receptor (OTR) oxytocin Gq chimera (mGoqi) complex
分子名称: Antibody fragment scFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Waltenspuhl, Y, Ehrenmann, J, Vacca, S, Thom, C, Medalia, O, Pluckthun, A.
登録日2022-01-21
公開日2022-08-10
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structural basis for the activation and ligand recognition of the human oxytocin receptor.
Nat Commun, 13, 2022
7P00
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Human Neurokinin 1 receptor (NK1R) substance P Gq chimera (mGsqi) complex
分子名称: Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Thom, C, Ehrenmann, J, Vacca, S, Waltenspuhl, Y, Schoppe, J, Medalia, O, Pluckthun, A.
登録日2021-06-29
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (2.71 Å)
主引用文献Structures of neurokinin 1 receptor in complex with G q and G s proteins reveal substance P binding mode and unique activation features.
Sci Adv, 7, 2021
7P02
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BU of 7p02 by Molmil
Human Neurokinin 1 receptor (NK1R) substance P Gs complex
分子名称: Antibody fragment scFv16, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Thom, C, Ehrenmann, J, Vacca, S, Waltenspuhl, Y, Schoppe, J, Medalia, O, Pluckthun, A.
登録日2021-06-29
公開日2021-12-15
実験手法ELECTRON MICROSCOPY (2.87 Å)
主引用文献Structures of neurokinin 1 receptor in complex with G q and G s proteins reveal substance P binding mode and unique activation features.
Sci Adv, 7, 2021
6TPK
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Crystal structure of the human oxytocin receptor
分子名称: (3~{R},6~{R})-6-[(2~{S})-butan-2-yl]-3-(2,3-dihydro-1~{H}-inden-2-yl)-1-[(1~{R})-1-(2-methyl-1,3-oxazol-4-yl)-2-morpholin-4-yl-2-oxidanylidene-ethyl]piperazine-2,5-dione, CHOLESTEROL, DI(HYDROXYETHYL)ETHER, ...
著者Waltenspuehl, Y, Schoeppe, J, Ehrenmann, J, Kummer, L, Plueckthun, A.
登録日2019-12-13
公開日2020-08-05
最終更新日2020-09-02
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of the human oxytocin receptor.
Sci Adv, 6, 2020

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件を2024-07-24に公開中

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