5B1U
 
 | |
5AXR
 | |
5AYA
 | |
5B15
 | | Crystal Structure of Metallo-beta-Lactamase SMB-1 Bound to Hydrolyzed Doripenem | | 分子名称: | (2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-3-methyl-4-[(3~{S},5~{S})-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid, Metallo-beta-lactamase, SODIUM ION, ... | | 著者 | Wachino, J, Arakawa, Y. | | 登録日 | 2015-11-23 | | 公開日 | 2016-05-11 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | Crystal Structure of Metallo-beta-Lactamase SMB-1 Bound to Hydrolyzed Doripenem
To Be Published
|
|
8I52
 | |
5YD7
 | |
5Y5B
 | | Crystal Structure Of IMP-1 Metallo-beta-lactamase | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Metallo-beta-lactamase type 2, SULFATE ION, ... | | 著者 | Wachino, J. | | 登録日 | 2017-08-08 | | 公開日 | 2018-08-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | 4-Amino-2-Sulfanylbenzoic Acid as a Potent Subclass B3 Metallo-beta-Lactamase-Specific Inhibitor Applicable for Distinguishing Metallo-beta-Lactamase Subclasses.
Antimicrob.Agents Chemother., 63, 2019
|
|
5ZR8
 | |
3VQZ
 | | Crystal structure of metallo-beta-lactamase, SMB-1, in a complex with mercaptoacetic acid | | 分子名称: | Metallo-beta-lactamase, SODIUM ION, SULFANYLACETIC ACID, ... | | 著者 | Wachino, J, Yamaguchi, Y, Mori, S, Arakawa, Y, Shibayama, K. | | 登録日 | 2012-04-02 | | 公開日 | 2013-02-13 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Insights into the Subclass B3 Metallo-beta-Lactamase SMB-1 and the Mode of Inhibition by the Common Metallo- -Lactamase Inhibitor Mercaptoacetate
Antimicrob.Agents Chemother., 57, 2013
|
|
3VPE
 | | Crystal Structure of Metallo-beta-Lactamase SMB-1 | | 分子名称: | ACETATE ION, GLYCEROL, Metallo-beta-lactamase, ... | | 著者 | Wachino, J, Yamaguchi, Y, Mori, S, Arakawa, Y, Shibayama, K. | | 登録日 | 2012-02-29 | | 公開日 | 2013-02-13 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural Insights into the Subclass B3 Metallo-beta-Lactamase SMB-1 and the Mode of Inhibition by the Common Metallo- -Lactamase Inhibitor Mercaptoacetate
Antimicrob.Agents Chemother., 57, 2013
|
|
5AXO
 | | Crystal Structure of Metallo-beta-Lactamase SMB-1 Bound to Hydrolyzed Meropenem | | 分子名称: | (2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-(dimethylcarbamoy l)pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Metallo-beta-lactamase, ... | | 著者 | Wachino, J, Arakawa, Y. | | 登録日 | 2015-07-31 | | 公開日 | 2016-05-11 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | Crystal Structure of Metallo-beta-Lactamase SMB-1 Bound to Hydrolyzed Meropenem
To Be Published
|
|
6JED
 | | Crystal structure of IMP-1 metallo-beta-lactamase in a complex with MCR | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Metallo-beta-lactamase type 2, SULFANYLACETIC ACID, ... | | 著者 | Wachino, J. | | 登録日 | 2019-02-05 | | 公開日 | 2019-08-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | 4-Amino-2-Sulfanylbenzoic Acid as a Potent Subclass B3 Metallo-beta-Lactamase-Specific Inhibitor Applicable for Distinguishing Metallo-beta-Lactamase Subclasses.
Antimicrob.Agents Chemother., 63, 2019
|
|
6K4T
 | | Crystal structure of SMB-1 metallo-beta-lactamase in a complex with TSA | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-sulfanylbenzoic acid, Metallo-beta-lactamase, ... | | 著者 | Wachino, J. | | 登録日 | 2019-05-27 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | 4-Amino-2-Sulfanylbenzoic Acid as a Potent Subclass B3 Metallo-beta-Lactamase-Specific Inhibitor Applicable for Distinguishing Metallo-beta-Lactamase Subclasses.
Antimicrob.Agents Chemother., 63, 2019
|
|
6K4X
 | | Crystal structure of SMB-1 metallo-beta-lactamase in a complex with ASB | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-azanyl-2-sulfanyl-benzoic acid, Metallo-beta-lactamase, ... | | 著者 | Wachino, J. | | 登録日 | 2019-05-27 | | 公開日 | 2019-08-07 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.17 Å) | | 主引用文献 | 4-Amino-2-Sulfanylbenzoic Acid as a Potent Subclass B3 Metallo-beta-Lactamase-Specific Inhibitor Applicable for Distinguishing Metallo-beta-Lactamase Subclasses.
Antimicrob.Agents Chemother., 63, 2019
|
|
5X5G
 | | Crystal structure of TLA-3 extended-spectrum beta-lactamase in a complex with OP0595 | | 分子名称: | (2S,5R)-N-(2-aminoethoxy)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase, SODIUM ION, ... | | 著者 | Wachino, J, Jin, W, Arakawa, Y. | | 登録日 | 2017-02-15 | | 公開日 | 2017-07-12 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Insights into the TLA-3 Extended-Spectrum beta-Lactamase and Its Inhibition by Avibactam and OP0595.
Antimicrob. Agents Chemother., 61, 2017
|
|
5GS8
 | | Crystal structure of TLA-3 extended-spectrum beta-lactamase | | 分子名称: | Beta-lactamase, CHLORIDE ION, SODIUM ION, ... | | 著者 | Wachino, J, Jin, W, Arakawa, Y. | | 登録日 | 2016-08-14 | | 公開日 | 2017-07-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Structural Insights into the TLA-3 Extended-Spectrum beta-Lactamase and Its Inhibition by Avibactam and OP0595.
Antimicrob. Agents Chemother., 61, 2017
|
|
5GWA
 | | Crystal structure of TLA-3 extended-spectrum beta-lactamase in a complex with avibactam | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase, CHLORIDE ION, ... | | 著者 | Wachino, J, Jin, W, Arakawa, Y. | | 登録日 | 2016-09-09 | | 公開日 | 2017-07-12 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Structural Insights into the TLA-3 Extended-Spectrum beta-Lactamase and Its Inhibition by Avibactam and OP0595.
Antimicrob. Agents Chemother., 61, 2017
|
|
4J1R
 | | Crystal Structure of GSK3b in complex with inhibitor 15R | | 分子名称: | (2R)-2-(1H-indol-3-ylmethyl)-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one, Glycogen synthase kinase-3 beta, PHOSPHATE ION, ... | | 著者 | Zhan, C, Wang, Y, Wach, J, Sheehan, P, Zhong, C, Harris, R, Patskovsky, Y, Bishop, J, Haggarty, S, Ramek, A, Berry, K, O'Herin, C, Koehler, A.N, Hung, A.W, Young, D.W, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2013-02-01 | | 公開日 | 2013-03-20 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | | 主引用文献 | Fragment-based approach using diversity-oriented synthesis yields a GSK3b inhibitor
To be Published
|
|
4J71
 | | Crystal Structure of GSK3b in complex with inhibitor 1R | | 分子名称: | (2R)-2-methyl-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one, CHLORIDE ION, Glycogen synthase kinase-3 beta, ... | | 著者 | Zhan, C, Wang, Y, Wach, J, Sheehan, P, Zhong, C, Harris, R, Patskovsky, Y, Bishop, J, Haggarty, S, Ramek, A, Berry, K, O'Herin, C, Koehler, A.N, Hung, A.W, Young, D.W, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2013-02-12 | | 公開日 | 2013-03-20 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Fragment-based approach using diversity-oriented synthesis yields a GSK3b inhibitor
To be Published
|
|
3ANO
 | | Crystal Structure of a Novel Diadenosine 5',5'''-P1,P4-Tetraphosphate Phosphorylase from Mycobacterium tuberculosis H37Rv | | 分子名称: | AP-4-A phosphorylase, PHOSPHATE ION, TETRAETHYLENE GLYCOL | | 著者 | Mori, S, Shibayama, K, Wachino, J, Arakawa, Y. | | 登録日 | 2010-09-06 | | 公開日 | 2011-05-18 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.894 Å) | | 主引用文献 | Structural insights into the novel diadenosine 5',5-P1,P4-tetraphosphate phosphorylase from Mycobacterium tuberculosis H37Rv
J.Mol.Biol., 410, 2011
|
|
5HI8
 | | Structure of T-type Phycobiliprotein Lyase CpeT from Prochlorococcus phage P-HM1 | | 分子名称: | ACETATE ION, Antenna protein, MAGNESIUM ION | | 著者 | Gasper, R, Schwach, J, Frankenberg-Dinkel, N, Hofmann, E. | | 登録日 | 2016-01-11 | | 公開日 | 2017-01-18 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Distinct Features of Cyanophage-encoded T-type Phycobiliprotein Lyase Phi CpeT: THE ROLE OF AUXILIARY METABOLIC GENES.
J. Biol. Chem., 292, 2017
|
|
4UBQ
 | | Crystal Structure of IMP-2 Metallo-beta-Lactamase from Acinetobacter spp. | | 分子名称: | ACETATE ION, Beta-lactamase, ZINC ION | | 著者 | Yamaguchi, Y, Matsueda, S, Matsunaga, K, Takashio, N, Toma-Fukai, S, Yamagata, Y, Shibata, N, Wachino, J, Shibayama, K, Arakawa, Y, Kurosaki, H. | | 登録日 | 2014-08-13 | | 公開日 | 2014-12-24 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of IMP-2 metallo-beta-lactamase from Acinetobacter spp.: comparison of active-site loop structures between IMP-1 and IMP-2.
Biol.Pharm.Bull., 38, 2015
|
|
2N9Q
 | | Photoswitchable G-quadruplex | | 分子名称: | DNA (5'-D(*GP*GP*(AZW)P*GP*G)-3'), POTASSIUM ION | | 著者 | Thevarpadam, J, Bessi, I, Binas, O, Goncalves, D.P.N, Slavov, C, Jonker, H.R.A, Richter, C, Wachtveitl, J, Schwalbe, H, Heckel, A. | | 登録日 | 2015-12-02 | | 公開日 | 2016-02-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Photoresponsive Formation of an Intermolecular Minimal G-Quadruplex Motif.
Angew.Chem.Int.Ed.Engl., 55, 2016
|
|
2ZJ9
 | | X-ray crystal structure of AmpC beta-Lactamase (AmpC(D)) from an Escherichia coli with a Tripeptide Deletion (Gly286 Ser287 Asp288) on the H10 Helix | | 分子名称: | AmpC, ISOPROPYL ALCOHOL, SODIUM ION | | 著者 | Yamaguchi, Y, Sato, G, Yamagata, Y, Wachino, J, Arakawa, Y, Kurosaki, H. | | 登録日 | 2008-02-29 | | 公開日 | 2009-03-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure of AmpC beta-lactamase (AmpCD) from an Escherichia coli clinical isolate with a tripeptide deletion (Gly286-Ser287-Asp288) in the H10 helix
Acta Crystallogr.,Sect.F, 65, 2009
|
|
4B2K
 | | COMPLEXES OF DODECIN WITH FLAVIN AND FLAVIN-LIKE LIGANDS | | 分子名称: | CHLORIDE ION, DODECIN, MAGNESIUM ION, ... | | 著者 | Staudt, H, Hoesl, M, Dreuw, A, Serdjukow, S, Oesterhelt, D, Budisa, N, Wachtveitl, J, Grininger, M. | | 登録日 | 2012-07-16 | | 公開日 | 2013-07-17 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Directed Manipulation of a Flavoprotein Photocycle.
Angew.Chem.Int.Ed.Engl., 52, 2013
|
|
