6EZA
| Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain E294K mutant | 分子名称: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | 著者 | Bou-Nader, C, Bregeon, D, Pecqueur, L, Vincent, G, Fontecave, M, Hamdane, D. | 登録日 | 2017-11-14 | 公開日 | 2018-09-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases. Biochemistry, 57, 2018
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6EZC
| Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain E294K Q305K double mutant | 分子名称: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | 著者 | Bou-Nader, C, Bregeon, D, Vincent, G, Fontecave, M, Hamdane, D. | 登録日 | 2017-11-14 | 公開日 | 2018-09-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases. Biochemistry, 57, 2018
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4YKN
| Pi3K alpha lipid kinase with Active Site Inhibitor | 分子名称: | 3-(6-methoxypyridin-3-yl)-5-[({4-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfamoyl]phenyl}amino)methyl]benzoic acid, Phosphatidylinositol 3-kinase regulatory subunit alpha,Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform fusion protein | 著者 | Elkins, P.A. | 登録日 | 2015-03-04 | 公開日 | 2015-06-17 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Discovery of a Potent Class of PI3K alpha Inhibitors with Unique Binding Mode via Encoded Library Technology (ELT). Acs Med.Chem.Lett., 6, 2015
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