8TB5
 
 | | TYK2 JH2 bound to Compound7 | | 分子名称: | ACETATE ION, N-{(3P)-3-[3-(dimethylsulfamoyl)phenyl]-1H-pyrrolo[2,3-c]pyridin-5-yl}cyclopropanecarboxamide, Non-receptor tyrosine-protein kinase TYK2 | | 著者 | Argiriadi, M.A, Van Epps, S.A, Breinlinger, E.C. | | 登録日 | 2023-06-28 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Targeting the Tyrosine Kinase 2 (TYK2) Pseudokinase Domain: Discovery of the Selective TYK2 Inhibitor ABBV-712.
J.Med.Chem., 66, 2023
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8TB6
 | | TYK2 JH2 bound to Compound14 | | 分子名称: | N-[(3M)-3-{6-[(3R)-3-methoxyoxolan-3-yl]pyridin-2-yl}-1-methyl-1H-pyrrolo[2,3-c]pyridin-5-yl]urea, Non-receptor tyrosine-protein kinase TYK2 | | 著者 | Argiriadi, M.A, Van Epps, S.A, Breinlinger, E.C. | | 登録日 | 2023-06-28 | | 公開日 | 2023-10-18 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Targeting the Tyrosine Kinase 2 (TYK2) Pseudokinase Domain: Discovery of the Selective TYK2 Inhibitor ABBV-712.
J.Med.Chem., 66, 2023
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