4UXU
 
 | | Crystal Structure of the Extracellular Domain of the Human Alpha9 Nicotinic Acetylcholine Receptor In Complex with Methyllycaconitine | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Zouridakis, M, Giastas, P, Zarkadas, E, Tzartos, S.J. | | 登録日 | 2014-08-27 | | 公開日 | 2014-10-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Crystal Structures of Free and Antagonist-Bound States of Human Alpha9 Nicotinic Receptor Extracellular Domain
Nat.Struct.Mol.Biol., 21, 2014
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1TOR
 | | MOLECULAR DYNAMICS SIMULATION FROM 2D-NMR DATA OF THE FREE ACHR MIR DECAPEPTIDE AND THE ANTIBODY-BOUND [A76]MIR ANALOGUE | | 分子名称: | ACETYLCHOLINE RECEPTOR, MAIN IMMUNOGENIC REGION | | 著者 | Orlewski, P, Tsikaris, V, Sakarellos, C, Sakarellos-Daistiotis, M, Vatzaki, E, Tzartos, S.J, Marraud, M, Cung, M.T. | | 登録日 | 1995-10-11 | | 公開日 | 1996-03-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Compared structures of the free nicotinic acetylcholine receptor main immunogenic region (MIR) decapeptide and the antibody-bound [A76]MIR analogue: a molecular dynamics simulation from two-dimensional NMR data.
Biopolymers, 40, 1996
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1TOS
 | | TORPEDO CALIFORNICA ACHR RECEPTOR [ALA76] ANALOGUE COMPLEXED WITH THE ANTI-ACETYLCHOLINE MAB6 MONOCLONAL ANTIBODY | | 分子名称: | ACETYLCHOLINE RECEPTOR [ALA76] MIR ANALOGUE | | 著者 | Orlewski, P, Tsikaris, V, Sakarellos, C, Sakarellos-Daistiotis, M, Vatzaki, E, Tzartos, S.J, Marraud, M, Cung, M.T. | | 登録日 | 1995-10-11 | | 公開日 | 1996-03-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Compared structures of the free nicotinic acetylcholine receptor main immunogenic region (MIR) decapeptide and the antibody-bound [A76]MIR analogue: a molecular dynamics simulation from two-dimensional NMR data.
Biopolymers, 40, 1996
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4UY2
 | | Crystal structure of the complex of the extracellular domain of human alpha9 nAChR with alpha-bungarotoxin. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-BUNGAROTOXIN ISOFORM V31, NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-9 | | 著者 | Giastas, P, Zouridakis, M, Zarkadas, E, Tzartos, S.J. | | 登録日 | 2014-08-28 | | 公開日 | 2014-10-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.697 Å) | | 主引用文献 | Crystal Structures of Free and Antagonist-Bound States of Human Alpha9 Nicotinic Receptor Extracellular Domain
Nat.Struct.Mol.Biol., 21, 2014
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5FJV
 | | Crystal structure of the extracellular domain of alpha2 nicotinic acetylcholine receptor in pentameric assembly | | 分子名称: | EPIBATIDINE, NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-2 | | 著者 | Giastas, P, Kouvatsos, N, Chroni-Tzartou, D, Tzartos, S.J. | | 登録日 | 2015-10-13 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal Structure of a Human Neuronal Nachr Extracellular Domain in Pentameric Assembly: Ligand-Bound Alpah2 Homopentamer.
Proc.Natl.Acad.Sci.USA, 113, 2016
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1C5D
 | | THE CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF A RAT MONOCLONAL ANTIBODY AGAINST THE MAIN IMMUNOGENIC REGION OF THE HUMAN MUSCLE ACETYLCHOLINE RECEPTOR | | 分子名称: | MONOCLONAL ANTIBODY AGAINST THE MAIN IMMUNOGENIC REGION OF THE HUMAN MUSCLE ACETYLCHOLINE RECEPTOR | | 著者 | Kontou, M, Leonidas, D.D, Vatzaki, E.H, Tsantili, P, Mamalaki, A, Oikonomakos, N.G, Acharya, K.R, Tzartos, S.J. | | 登録日 | 1999-11-17 | | 公開日 | 1999-12-03 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The crystal structure of the Fab fragment of a rat monoclonal antibody against the main immunogenic region of the human muscle acetylcholine receptor.
Eur.J.Biochem., 267, 2000
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4D01
 | | Crystal Structure of the Extracellular Domain of the Human Alpha9 Nicotinic Acetylcholine Receptor | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-9 | | 著者 | Giastas, P, Zouridakis, M, Zarkadas, E, Tzartos, S.J. | | 登録日 | 2014-04-23 | | 公開日 | 2014-10-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.795 Å) | | 主引用文献 | Crystal Structures of Free and Antagonist-Bound States of Human Alpha9 Nicotinic Receptor Extracellular Domain
Nat.Struct.Mol.Biol., 21, 2014
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5N1P
 | | Crystal structure of the polysaccharide deacetylase Bc1974 from Bacillus cereus in complex with N-hydroxynaphthalene-1-carboxamide | | 分子名称: | 1,2-ETHANEDIOL, Peptidoglycan N-acetylglucosamine deacetylase, SODIUM ION, ... | | 著者 | Giastas, P, Andreou, A, Eliopoulos, E.E. | | 登録日 | 2017-02-06 | | 公開日 | 2018-02-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.448 Å) | | 主引用文献 | Structures of the Peptidoglycan N-Acetylglucosamine Deacetylase Bc1974 and Its Complexes with Zinc Metalloenzyme Inhibitors.
Biochemistry, 57, 2018
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5NCD
 | | Crystal structure of the polysaccharide deacetylase Bc1974 from Bacillus cereus in complex with (2S)-2-amino-5-(diaminomethylideneamino)-N-hydroxypentanamide | | 分子名称: | ACETATE ION, CITRIC ACID, N-HYDROXY-L-ARGININAMIDE, ... | | 著者 | Giastas, P, Andreou, A, Eliopoulos, E.E. | | 登録日 | 2017-03-03 | | 公開日 | 2018-02-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.447 Å) | | 主引用文献 | Structures of the Peptidoglycan N-Acetylglucosamine Deacetylase Bc1974 and Its Complexes with Zinc Metalloenzyme Inhibitors.
Biochemistry, 57, 2018
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5NC9
 | | Crystal structure of the polysaccharide deacetylase Bc1974 from Bacillus cereus in complex with (2S)-2,6-diamino-N-hydroxyhexanamide | | 分子名称: | (2~{S})-2,6-bis(azanyl)-~{N}-oxidanyl-hexanamide, 1,2-ETHANEDIOL, CITRIC ACID, ... | | 著者 | Giastas, P, Andreou, A, Eliopoulos, E.E. | | 登録日 | 2017-03-03 | | 公開日 | 2018-02-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Structures of the Peptidoglycan N-Acetylglucosamine Deacetylase Bc1974 and Its Complexes with Zinc Metalloenzyme Inhibitors.
Biochemistry, 57, 2018
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5NC6
 | | Crystal structure of the polysaccharide deacetylase Bc1974 from Bacillus cereus in complex with (E)-N-hydroxy-3-(naphthalen-1-yl)prop-2-enamide | | 分子名称: | 1,2-ETHANEDIOL, 3-naphthalen-1-yl-~{N}-oxidanyl-propanamide, ACETATE ION, ... | | 著者 | Giastas, P, Andreou, A, Balomenou, S, Bouriotis, V, Eliopoulos, E.E. | | 登録日 | 2017-03-03 | | 公開日 | 2018-02-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of the Peptidoglycan N-Acetylglucosamine Deacetylase Bc1974 and Its Complexes with Zinc Metalloenzyme Inhibitors.
Biochemistry, 57, 2018
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5NEL
 | | Crystal structure of the polysaccharide deacetylase Bc1974 from Bacillus cereus in complex with ThiametG | | 分子名称: | (3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL)-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]THIAZOLE-6,7-DIOL, 1,2-ETHANEDIOL, ACETATE ION, ... | | 著者 | Andreou, A, Giastas, P, Eliopoulos, E.E. | | 登録日 | 2017-03-10 | | 公開日 | 2018-02-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.734 Å) | | 主引用文献 | Structures of the Peptidoglycan N-Acetylglucosamine Deacetylase Bc1974 and Its Complexes with Zinc Metalloenzyme Inhibitors.
Biochemistry, 57, 2018
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5NEK
 | | Crystal structure of the polysaccharide deacetylase Bc1974 from Bacillus cereus in complex with acetazolamide | | 分子名称: | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, ACETATE ION, Peptidoglycan N-acetylglucosamine deacetylase, ... | | 著者 | Andreou, A, Giastas, P, Eliopoulos, E.E. | | 登録日 | 2017-03-10 | | 公開日 | 2018-02-21 | | 最終更新日 | 2019-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.057 Å) | | 主引用文献 | Structures of the Peptidoglycan N-Acetylglucosamine Deacetylase Bc1974 and Its Complexes with Zinc Metalloenzyme Inhibitors.
Biochemistry, 57, 2018
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1F3R
 | | COMPLEX BETWEEN FV ANTIBODY FRAGMENT AND AN ANALOGUE OF THE MAIN IMMUNOGENIC REGION OF THE ACETYLCHOLINE RECEPTOR | | 分子名称: | ACETYLCHOLINE RECEPTOR ALPHA, FV ANTIBODY FRAGMENT | | 著者 | Kleinjung, J, Petit, M.-C, Orlewski, P, Mamalaki, A, Tzartos, S.-J, Tsikaris, V, Sakarellos-Daitsiotis, M, Sakarellos, C, Marraud, M, Cung, M.-T. | | 登録日 | 2000-06-06 | | 公開日 | 2000-06-15 | | 最終更新日 | 2021-11-03 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The third-dimensional structure of the complex between an Fv antibody fragment and an analogue of the main immunogenic region of the acetylcholine receptor: a combined two-dimensional NMR, homology, and molecular modeling approach.
Biopolymers, 53, 2000
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4V33
 | | Crystal structure of the putative polysaccharide deacetylase BA0330 from bacillus anthracis | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, POLYSACCHARIDE DEACETYLASE-LIKE PROTEIN, ... | | 著者 | Giastas, P, Andreou, A, Bouriotis, V, Eliopoulos, E. | | 登録日 | 2014-10-16 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Two Putative Polysaccharide Deacetylases are Required for Osmotic Stability and Cell Shape Maintenance in Bacillus Anthracis.
J.Biol.Chem., 290, 2015
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5N1J
 | | Crystal structure of the polysaccharide deacetylase Bc1974 from Bacillus cereus | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Peptidoglycan N-acetylglucosamine deacetylase, ... | | 著者 | Giastas, P, Andreou, A, Balomenou, S, Bouriotis, V, Eliopoulos, E.E. | | 登録日 | 2017-02-06 | | 公開日 | 2018-02-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of the Peptidoglycan N-Acetylglucosamine Deacetylase Bc1974 and Its Complexes with Zinc Metalloenzyme Inhibitors.
Biochemistry, 57, 2018
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8A5U
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6GO1
 | | Crystal Structure of a Bacillus anthracis peptidoglycan deacetylase | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Polysaccharide deacetylase-like protein, ... | | 著者 | Giastas, P, Andreou, A, Eliopoulos, E.E. | | 登録日 | 2018-06-01 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | The putative polysaccharide deacetylase Ba0331: cloning, expression, crystallization and structure determination.
Acta Crystallogr.,Sect.F, 75, 2019
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1FN4
 | | CRYSTAL STRUCTURE OF FAB198, AN EFFICIENT PROTECTOR OF ACETYLCHOLINE RECEPTOR AGAINST MYASTHENOGENIC ANTIBODIES | | 分子名称: | MONOCLONAL ANTIBODY AGAINST ACETYLCHOLINE RECEPTOR | | 著者 | Poulas, K, Eliopoulos, E, Vatzaki, E, Navaza, J, Kontou, M. | | 登録日 | 2000-08-21 | | 公開日 | 2001-09-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of Fab198, an efficient protector of the acetylcholine receptor against myasthenogenic antibodies.
Eur.J.Biochem., 268, 2001
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