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5L7I
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BU of 5l7i by Molmil
Structure of human Smoothened in complex with Vismodegib
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-chloranyl-~{N}-(4-chloranyl-3-pyridin-2-yl-phenyl)-4-methylsulfonyl-benzamide, SODIUM ION, ...
著者Byrne, E.X.B, Sircar, R, Miller, P.S, Hedger, G, Luchetti, G, Nachtergaele, S, Tully, M.D, Mydock-McGrane, L, Covey, D.F, Rambo, R.F, Sansom, M.S.P, Newstead, S, Rohatgi, R, Siebold, C.
登録日2016-06-03
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis of Smoothened regulation by its extracellular domains.
Nature, 535, 2016
5L7D
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BU of 5l7d by Molmil
Structure of human Smoothened in complex with cholesterol
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, SODIUM ION, ...
著者Byrne, E.F.X, Sircar, R, Miller, P.S, Hedger, G, Luchetti, G, Nachtergaele, S, Tully, M.D, Mydock-McGrane, L, Covey, D.F, Rambo, R.P, Sansom, M.S.P, Newstead, S, Rohatgi, R, Siebold, C.
登録日2016-06-03
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis of Smoothened regulation by its extracellular domains.
Nature, 535, 2016
8BLQ
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BU of 8blq by Molmil
Cryo-EM structure of the CODV-IL13-RefAb triple complex
分子名称: CODV-Fab, heavy chain, light chain, ...
著者Fernandez-Martinez, D, Kandiah, E.
登録日2022-11-10
公開日2023-06-07
実験手法ELECTRON MICROSCOPY (3.97 Å)
主引用文献Structural insights into the bi-specific cross-over dual variable antibody architecture by cryo-EM.
Sci Rep, 13, 2023
6H7X
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BU of 6h7x by Molmil
First X-ray structure of full-length human RuvB-Like 2.
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
著者Silva, S, Brito, J.A, Matias, P, Bandeiras, T.
登録日2018-07-31
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.892 Å)
主引用文献X-ray structure of full-length human RuvB-Like 2 - mechanistic insights into coupling between ATP binding and mechanical action.
Sci Rep, 8, 2018
6GFE
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BU of 6gfe by Molmil
High-resolution Structure of a therapeutic full-length anti-NPRA Antibody with exceptional Conformational Diversity
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CALCIUM ION, ...
著者Hoerer, S.
登録日2018-04-30
公開日2019-05-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of a Therapeutic Full-Length Anti-NPRA IgG4 Antibody: Dissecting Conformational Diversity.
Biophys.J., 116, 2019

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件を2024-10-16に公開中

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