5LXO
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5LXN
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2XOI
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![BU of 2xoi by Molmil](/molmil-images/mine/2xoi) | Functional and Structural Analyses of N-Acylsulfonamide-Linked Dinucleoside Inhibitors of Ribonuclease A | 分子名称: | (2S,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-N-[[(2S,3S,4R,5R)-5-(2,4-DIOXOPYRIMIDIN-1-YL)-4-HYDROXY-2-(HYDROXYMETHYL)OXOLAN-3-YL]METHYLSULFONYL]-3,4-DIHYDROXY-OXOLANE-2-CARBOXAMIDE, RIBONUCLEASE PANCREATIC | 著者 | Thiyagarajan, N, Smith, B.D, Raines, R.T, Acharya, K.R. | 登録日 | 2010-08-17 | 公開日 | 2011-01-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Functional and Structural Analyses of N-Acylsulfonamide-Linked Dinucleoside Inhibitors of Ribonuclease A. FEBS J., 278, 2011
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2XOG
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![BU of 2xog by Molmil](/molmil-images/mine/2xog) | Functional and Structural Analyses of N-Acylsulfonamide-Linked Dinucleoside Inhibitors of Ribonuclease A | 分子名称: | (2S,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-N-[[(2S,3S,4R,5R)-5-(2,4-DIOXOPYRIMIDIN-1-YL)-4-HYDROXY-2-(HYDROXYMETHYL)OXOLAN-3-YL]METHYLSULFONYL]-3,4-DIHYDROXY-OXOLANE-2-CARBOXAMIDE, RIBONUCLEASE PANCREATIC | 著者 | Thiyagarajan, N, Smith, B.D, Raines, R.T, Acharya, K.R. | 登録日 | 2010-08-16 | 公開日 | 2011-01-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Functional and Structural Analyses of N-Acylsulfonamide-Linked Dinucleoside Inhibitors of Ribonuclease A. FEBS J., 278, 2011
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4B36
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4AHK
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![BU of 4ahk by Molmil](/molmil-images/mine/4ahk) | K54E - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | 分子名称: | ANGIOGENIN, D(-)-TARTARIC ACID | 著者 | Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. | 登録日 | 2012-02-06 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
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4AOH
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![BU of 4aoh by Molmil](/molmil-images/mine/4aoh) | Structural snapshots and functional analysis of human angiogenin variants associated with Amyotrophic Lateral Sclerosis (ALS) | 分子名称: | ANGIOGENIN, D(-)-TARTARIC ACID, L(+)-TARTARIC ACID | 著者 | Thiyagarajan, N, Ferguson, R, Subramanian, V, Acharya, K.R. | 登録日 | 2012-03-27 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.041 Å) | 主引用文献 | Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons Nat.Commun., 3, 2012
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4AHJ
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![BU of 4ahj by Molmil](/molmil-images/mine/4ahj) | I46V - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | 分子名称: | ANGIOGENIN, D(-)-TARTARIC ACID | 著者 | Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. | 登録日 | 2012-02-06 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.032 Å) | 主引用文献 | Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
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4AHD
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![BU of 4ahd by Molmil](/molmil-images/mine/4ahd) | Q12L - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | 分子名称: | ANGIOGENIN | 著者 | Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. | 登録日 | 2012-02-06 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
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4AHN
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![BU of 4ahn by Molmil](/molmil-images/mine/4ahn) | R121H - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | 分子名称: | ANGIOGENIN, CHLORIDE ION | 著者 | Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. | 登録日 | 2012-02-06 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.977 Å) | 主引用文献 | Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
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4AHM
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![BU of 4ahm by Molmil](/molmil-images/mine/4ahm) | V113I - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | 分子名称: | ANGIOGENIN, L(+)-TARTARIC ACID | 著者 | Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. | 登録日 | 2012-02-06 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
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4AHI
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![BU of 4ahi by Molmil](/molmil-images/mine/4ahi) | K40I - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | 分子名称: | ANGIOGENIN | 著者 | Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. | 登録日 | 2012-02-06 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.798 Å) | 主引用文献 | Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
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4AHF
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![BU of 4ahf by Molmil](/molmil-images/mine/4ahf) | K17E - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | 分子名称: | 1,2-ETHANEDIOL, ANGIOGENIN, SULFATE ION | 著者 | Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. | 登録日 | 2012-02-06 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.115 Å) | 主引用文献 | Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
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4AHE
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![BU of 4ahe by Molmil](/molmil-images/mine/4ahe) | K17I - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | 分子名称: | ANGIOGENIN, L(+)-TARTARIC ACID | 著者 | Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. | 登録日 | 2012-02-06 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
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4AYL
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![BU of 4ayl by Molmil](/molmil-images/mine/4ayl) | Molecular structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, BOGT-METAL-INDEPENDENT GLYCOSYLTRANSFERASE, CALCIUM ION, ... | 著者 | Thiyagarajan, N, Pham, T.T.K, Stinsonb, B, Sundriyala, A, Tumbale, P, Lizotte-Waniewskib, M, Brewb, K, Acharya, K.R. | 登録日 | 2012-06-21 | 公開日 | 2012-12-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.919 Å) | 主引用文献 | Structure of a Metal-Independent Bacterial Glycosyltransferase that Catalyzes the Synthesis of Histo-Blood Group a Antigen Sci.Rep., 2, 2012
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4AHL
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![BU of 4ahl by Molmil](/molmil-images/mine/4ahl) | P112L - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | 分子名称: | ANGIOGENIN, L(+)-TARTARIC ACID | 著者 | Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. | 登録日 | 2012-02-06 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.053 Å) | 主引用文献 | Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
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4AHG
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![BU of 4ahg by Molmil](/molmil-images/mine/4ahg) | S28N - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | 分子名称: | ANGIOGENIN, D(-)-TARTARIC ACID | 著者 | Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. | 登録日 | 2012-02-06 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.448 Å) | 主引用文献 | Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
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4AYJ
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![BU of 4ayj by Molmil](/molmil-images/mine/4ayj) | Molecular structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen | 分子名称: | BOGT - METAL-INDEPENDENT GLYCOSYLTRANSFERASE, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | 著者 | Thiyagarajan, N, Pham, T.T.K, Stinson, B, Sundriyal, A, Tumbale, P, Lizotte-Waniewskib, M, Brewb, K, Acharya, K.R. | 登録日 | 2012-06-21 | 公開日 | 2012-12-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of a Metal-Independent Bacterial Glycosyltransferase that Catalyzes the Synthesis of Histo-Blood Group a Antigen Sci.Rep., 2, 2012
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4AHH
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![BU of 4ahh by Molmil](/molmil-images/mine/4ahh) | R31K - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis | 分子名称: | ANGIOGENIN, L(+)-TARTARIC ACID | 著者 | Thiyagarajan, N, Ferguson, R, Saha, S, Pham, T, Subramanian, V, Acharya, K.R. | 登録日 | 2012-02-06 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.498 Å) | 主引用文献 | Structural and Molecular Insights Into the Mechanism of Action of Human Angiogenin-Als Variants in Neurons. Nat.Commun., 3, 2012
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4UWY
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![BU of 4uwy by Molmil](/molmil-images/mine/4uwy) | FGFR1 Apo structure | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FIBROBLAST GROWTH FACTOR RECEPTOR 1 | 著者 | Thiyagarajan, N, Bunney, T, Katan, M. | 登録日 | 2014-08-15 | 公開日 | 2015-02-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.305 Å) | 主引用文献 | The Effect of Mutations on Drug Sensitivity and Kinase Activity of Fibroblast Growth Factor Receptors: A Combined Experimental and Theoretical Study Ebiomedicine, 2, 2015
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5FLF
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![BU of 5flf by Molmil](/molmil-images/mine/5flf) | DISEASE LINKED MUTATION IN FGFR | 分子名称: | ACETATE ION, CHLORIDE ION, FIBROBLAST GROWTH FACTOR RECEPTOR 1, ... | 著者 | Thiyagarajan, N, Bunney, T.D, Katan, M. | 登録日 | 2015-10-26 | 公開日 | 2016-03-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Landscape of Activating Cancer Mutations in Fgfr Kinases and Their Differential Responses to Inhibitors in Clinical Use. Oncotarget, 7, 2016
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2VS5
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![BU of 2vs5 by Molmil](/molmil-images/mine/2vs5) | THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF alpha-1,3 GALACTOSYLTRANSFERASE (alpha3GT) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, GALACTOSE-URIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... | 著者 | Tumbale, P, Jamaluddin, H, Thiyagarajan, N, Brew, K, Acharya, K.R. | 登録日 | 2008-04-18 | 公開日 | 2008-07-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Structural Basis of Udp-Galactose Binding by Alpha- 1,3-Galactosyltransferase (Alpha3Gt): Role of Negative Charge on Aspartic Acid 316 in Structure and Activity. Biochemistry, 47, 2008
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2VS3
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![BU of 2vs3 by Molmil](/molmil-images/mine/2vs3) | THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF alpha-1,3 GALACTOSYLTRANSFERASE (alpha3GT) | 分子名称: | MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, ... | 著者 | Tumbale, P, Jamaluddin, H, Thiyagarajan, N, Brew, K, Acharya, K.R. | 登録日 | 2008-04-18 | 公開日 | 2008-07-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Basis of Udp-Galactose Binding by Alpha- 1,3-Galactosyltransferase (Alpha3Gt): Role of Negative Charge on Aspartic Acid 316 in Structure and Activity. Biochemistry, 47, 2008
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2VS4
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![BU of 2vs4 by Molmil](/molmil-images/mine/2vs4) | THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF alpha-1,3 GALACTOSYLTRANSFERASE (alpha3GT) | 分子名称: | GLYCEROL, MANGANESE (II) ION, N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, ... | 著者 | Tumbale, P, Jamaluddin, H, Thiyagarajan, N, Brew, K, Acharya, K.R. | 登録日 | 2008-04-18 | 公開日 | 2008-07-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Structural Basis of Udp-Galactose Binding by Alpha- 1,3-Galactosyltransferase (Alpha3Gt): Role of Negative Charge on Aspartic Acid 316 in Structure and Activity. Biochemistry, 47, 2008
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2WD2
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![BU of 2wd2 by Molmil](/molmil-images/mine/2wd2) | A chimeric microtubule disruptor with efficacy on a taxane resistant cell line | 分子名称: | 7-methoxy-2-(3-methoxybenzyl)-1,2,3,4-tetrahydroisoquinolin-6-yl sulfamate, CARBONIC ANHYDRASE 2, FORMIC ACID, ... | 著者 | Leese, M.P, Jourdan, F.L, Kimberley, M.R, Cozier, G.E, Regis-Lydi, S, Foster, P.A, Newman, S.P, Thiyagarajan, N, Acharya, K.R, Ferrandis, E, Purohit, A, Reed, M.J, Potter, B.V.L. | 登録日 | 2009-03-19 | 公開日 | 2010-03-31 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Chimeric Microtubule Disruptors. Chem.Commun.(Camb.), 46, 2010
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