8W7E
| Design, synthesis and biological evaluations of novel small molecular hyper-activators of human caseinolytic peptidase P (hClpP) | 分子名称: | 3-[(3-chlorophenyl)methyl]-6-[(4-chlorophenyl)methyl]-2,4-dihydro-1H-pyrido[2,3-c][2,7]naphthyridin-5-one, ATP-dependent Clp protease proteolytic subunit, mitochondrial | 著者 | Jiang, J.-X, Ding, H, Chen, M.-R, Lu, M.-L, Sun, H.-Y, Xiao, Y.-B. | 登録日 | 2023-08-30 | 公開日 | 2024-09-04 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Design, synthesis and biological evaluations of novel small molecular hyper-activators of human caseinolytic peptidase P (hClpP) To Be Published
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8W7C
| Activation of mitochondrial Caseinolytic Protease P (ClpP) induces selective cancer cell lethality | 分子名称: | 11-[(3-chlorophenyl)methyl]-7-[[4-(trifluoromethyl)phenyl]methyl]-2,5,7,11-tetrazatricyclo[7.4.0.0^{2,6}]trideca-1(9),3,5-trien-8-one, ATP-dependent Clp protease proteolytic subunit, mitochondrial | 著者 | Jiang, J.-X, Ding, H, Lu, M.-L, Chen, M.-R, Sun, H.-Y, Xiao, Y.-B. | 登録日 | 2023-08-30 | 公開日 | 2024-09-04 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Activation of mitochondrial Caseinolytic Protease P (ClpP) induces selective cancer cell lethality To Be Published
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8WUZ
| Development of 2-imino-2,3,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-4(1H)-one derivatives as human caseinolytic peptidase P (hClpP) activators | 分子名称: | 5-[(3-fluorophenyl)methyl]-9-[[4-(trifluoromethyl)phenyl]methyl]-1,5,9,11-tetrazatricyclo[8.4.0.0^{2,7}]tetradeca-2(7),10-dien-8-one, ATP-dependent Clp protease proteolytic subunit, mitochondrial, ... | 著者 | Jiang, J.-X, Ding, H, Chen, M.-R, Lu, M.-L, Sun, H.-Y, Xiao, Y.-B. | 登録日 | 2023-10-22 | 公開日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Development of 2-imino-2,3,5,6,7,8-hexahydropyrido[4,3-d]pyrimidin-4(1H)-one derivatives as human caseinolytic peptidase P (hClpP) activators To Be Published
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