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BU of 8jzw by Molmil

Cystal structure of HP1 in complex with TRIM66 peptide
分子名称:	ASN-SER-GLU-HIS-LYS-ILE-PRO-TYR-VAL-ARG-LEU-GLU-ARG-LEU-LYS-ILE-CYS-ALA, Chromobox homolog 3 (HP1 gamma homolog, Drosophila)
著者	Shen, S.Y, Li, F.D, Shi, Y.Y.
登録日	2023-07-06
公開日	2024-07-10
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Cystal structure of HP1 in complex with TRIM66 peptide To Be Published

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BU of 8ikh by Molmil

Cryo-EM structure of human receptor with G proteins
分子名称:	3-[(1R)-1-(2-methoxyphenyl)-2-nitro-ethyl]-2-phenyl-1H-indole, Cannabinoid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者	Shen, S.Y, Shao, Z.H.
登録日	2023-02-28
公開日	2024-06-05
最終更新日	2024-07-17
実験手法	ELECTRON MICROSCOPY (3.3 Å)
主引用文献	Structure-based identification of a G protein-biased allosteric modulator of cannabinoid receptor CB1. Proc.Natl.Acad.Sci.USA, 121, 2024

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BU of 8ikg by Molmil

Cryo-EM structure of human receptor with G proteins
分子名称:	3-[(1S)-1-(furan-2-yl)-2-nitro-ethyl]-2-phenyl-1H-indole, Cannabinoid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者	Shen, S.Y, Shao, Z.H.
登録日	2023-02-28
公開日	2024-06-05
最終更新日	2024-07-17
実験手法	ELECTRON MICROSCOPY (3.4 Å)
主引用文献	Structure-based identification of a G protein-biased allosteric modulator of cannabinoid receptor CB1. Proc.Natl.Acad.Sci.USA, 121, 2024

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BU of 7eiu by Molmil

Crystal structure of Mei2 RRM3 in complex with 8mer meiRNA
分子名称:	GLYCEROL, Meiosis protein mei2, RNA (5'-R(PUPUPCPUPGPC)-3')
著者	Shen, S.Y, Lv, M.Q.
登録日	2021-03-31
公開日	2022-04-06
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (2.349 Å)
主引用文献	Structural insights reveal the specific recognition of meiRNA by the Mei2 protein. J Mol Cell Biol, 14, 2022

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BU of 7eio by Molmil

Crystal Structure of Mei2 RRM3
分子名称:	GLYCEROL, Meiosis protein mei2, SULFATE ION
著者	Shen, S.Y, Li, F.D.
登録日	2021-03-31
公開日	2022-04-06
最終更新日	2024-05-29
実験手法	X-RAY DIFFRACTION (1.895 Å)
主引用文献	Structural insights reveal the specific recognition of meiRNA by the Mei2 protein. J Mol Cell Biol, 14, 2022

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BU of 8jlp by Molmil

Ralmitaront(RO-6889450)-bound hTAAR1-Gs protein complex
分子名称:	5-ethyl-4-methyl-~{N}-[4-[(2~{S})-morpholin-2-yl]phenyl]-1~{H}-pyrazole-3-carboxamide, Gs, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者	Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H.
登録日	2023-06-02
公開日	2023-11-15
最終更新日	2024-01-03
実験手法	ELECTRON MICROSCOPY (3.23 Å)
主引用文献	Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023

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BU of 8jlk by Molmil

Ulotaront(SEP-363856)-bound mTAAR1-Gs protein complex
分子名称:	1-[(7~{S})-5,7-dihydro-4~{H}-thieno[2,3-c]pyran-7-yl]-~{N}-methyl-methanamine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者	Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H.
登録日	2023-06-02
公開日	2023-11-15
最終更新日	2024-01-03
実験手法	ELECTRON MICROSCOPY (3.22 Å)
主引用文献	Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023

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BU of 8jlq by Molmil

Fenoldopam-bound hTAAR1-Gs protein complex
分子名称:	(1R)-6-chloranyl-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者	Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H.
登録日	2023-06-02
公開日	2023-11-15
最終更新日	2024-01-03
実験手法	ELECTRON MICROSCOPY (2.84 Å)
主引用文献	Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023

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BU of 8jln by Molmil

T1AM-bound hTAAR1-Gs protein complex
分子名称:	4-[4-(2-azanylethyl)-2-iodanyl-phenoxy]phenol, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者	Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H.
登録日	2023-06-02
公開日	2023-11-15
最終更新日	2024-01-03
実験手法	ELECTRON MICROSCOPY (3.24 Å)
主引用文献	Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023

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BU of 8jlo by Molmil

Ulotaront(SEP-363856)-bound hTAAR1-Gs protein complex
分子名称:	1-[(7~{S})-5,7-dihydro-4~{H}-thieno[2,3-c]pyran-7-yl]-~{N}-methyl-methanamine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者	Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H.
登録日	2023-06-02
公開日	2023-11-15
最終更新日	2024-01-03
実験手法	ELECTRON MICROSCOPY (3.52 Å)
主引用文献	Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023

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BU of 8jlj by Molmil

T1AM-bound mTAAR1-Gs protein complex
分子名称:	4-[4-(2-azanylethyl)-2-iodanyl-phenoxy]phenol, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者	Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H.
登録日	2023-06-02
公開日	2023-11-15
最終更新日	2024-01-03
実験手法	ELECTRON MICROSCOPY (3.1 Å)
主引用文献	Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023

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BU of 8jlr by Molmil

A77636-bound hTAAR1-Gs protein complex
分子名称:	(1~{S},3~{R})-3-(1-adamantyl)-1-(aminomethyl)-3,4-dihydro-1~{H}-isochromene-5,6-diol, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者	Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H.
登録日	2023-06-02
公開日	2023-11-15
最終更新日	2024-01-03
実験手法	ELECTRON MICROSCOPY (3 Å)
主引用文献	Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023

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BU of 8jsp by Molmil

Ulotaront(SEP-363856)-bound Serotonin 1A (5-HT1A) receptor-Gi complex
分子名称:	1-[(7~{S})-5,7-dihydro-4~{H}-thieno[2,3-c]pyran-7-yl]-~{N}-methyl-methanamine, 5-hydroxytryptamine receptor 1A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者	Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H.
登録日	2023-06-20
公開日	2023-11-15
最終更新日	2024-01-03
実験手法	ELECTRON MICROSCOPY (3.65 Å)
主引用文献	Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023

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BU of 8jso by Molmil

AMPH-bound hTAAR1-Gs protein complex
分子名称:	(2S)-1-phenylpropan-2-amine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者	Xu, Z, Guo, L.L, Zhao, C, Shen, S.Y, Sun, J.P, Shao, Z.H.
登録日	2023-06-20
公開日	2023-11-15
最終更新日	2024-01-03
実験手法	ELECTRON MICROSCOPY (3.4 Å)
主引用文献	Ligand recognition and G-protein coupling of trace amine receptor TAAR1. Nature, 624, 2023

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件を2024-07-17に公開中

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