2V9Z
 
 | | Structure of the Rhodococcus haloalkane dehalogenase mutant with enhanced enantioselectivity | | 分子名称: | HALOALKANE DEHALOGENASE | | 著者 | Koudelakova, T, Prokop, Z, Sato, Y, Lapkouski, M, Chovancova, E, Monincova, M, Jesenska, A, Emmer, J, Senda, T, Nagata, Y, Kuta Smatanova, I, Damborsky, J. | | 登録日 | 2007-08-28 | | 公開日 | 2008-09-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Rational Engineering of Rhodococcus Haloalkane Dehalogenase with Enhanced Enantioselectivity
To be Published
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1G42
 | | STRUCTURE OF 1,3,4,6-TETRACHLORO-1,4-CYCLOHEXADIENE HYDROLASE (LINB) FROM SPHINGOMONAS PAUCIMOBILIS COMPLEXED WITH 1,2-DICHLOROPROPANE | | 分子名称: | 1,2-DICHLORO-PROPANE, 1,3,4,6-TETRACHLORO-1,4-CYCLOHEXADIENE HYDROLASE, ACETATE ION, ... | | 著者 | Oakley, A.J, Prokop, Z, Bohac, M, Kmunicek, J, Jedlicka, T, Monincova, M, Kuta-Smatanova, I, Nagata, Y, Damborsky, J, Wilce, M.C.J. | | 登録日 | 2000-10-26 | | 公開日 | 2001-10-26 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Exploring the structure and activity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26: evidence for product- and water-mediated inhibition.
Biochemistry, 41, 2002
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1G4H
 | | LINB COMPLEXED WITH BUTAN-1-OL | | 分子名称: | 1,3,4,6-TETRACHLORO-1,4-CYCLOHEXADIENE HYDROLASE, 1-BUTANOL, CALCIUM ION, ... | | 著者 | Oakley, A.J, Prokop, Z, Bohac, M, Kmunicek, J, Jedlicka, T, Monincova, M, Kuta-Smatanova, I, Nagata, Y, Damborsky, J, Wilce, M.C.J. | | 登録日 | 2000-10-27 | | 公開日 | 2001-10-27 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Exploring the structure and activity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26: evidence for product- and water-mediated inhibition.
Biochemistry, 41, 2002
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1G5F
 | | STRUCTURE OF LINB COMPLEXED WITH 1,2-DICHLOROETHANE | | 分子名称: | 1,2-DICHLOROETHANE, 1,3,4,6-TETRACHLORO-1,4-CYCLOHEXADIENE HYDROLASE, CALCIUM ION, ... | | 著者 | Oakley, A.J, Prokop, Z, Bohac, M, Kmunicek, J, Jedlicka, T, Monincova, M, Kuta-Smatanova, I, Nagata, Y, Damborsky, J, Wilce, M.C.J. | | 登録日 | 2000-11-01 | | 公開日 | 2001-11-01 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Exploring the structure and activity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26: evidence for product- and water-mediated inhibition.
Biochemistry, 41, 2002
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1K6E
 | | COMPLEX OF HYDROLYTIC HALOALKANE DEHALOGENASE LINB FROM SPHINGOMONAS PAUCIMOBILIS UT26 WITH 1,2-PROPANEDIOL (PRODUCT OF DEHALOGENATION OF 1,2-DIBROMOPROPANE) AT 1.85A | | 分子名称: | 1-BROMOPROPANE-2-OL, BROMIDE ION, CHLORIDE ION, ... | | 著者 | Streltsov, V.A, Prokop, Z, Damborsky, J, Nagata, Y, Oakley, A, Wilce, M.C.J. | | 登録日 | 2001-10-16 | | 公開日 | 2003-08-19 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Haloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26: X-ray crystallographic studies of dehalogenation of brominated substrates.
Biochemistry, 42, 2003
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3A2M
 | | CRYSTAL STRUCTURE OF DBJA (WILD TYPE Type I) | | 分子名称: | CHLORIDE ION, Haloalkane dehalogenase, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | | 著者 | Sato, Y, Senda, T. | | 登録日 | 2009-05-23 | | 公開日 | 2010-05-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Enantioselectivity of haloalkane dehalogenases and its modulation by surface loop engineering
Angew.Chem.Int.Ed.Engl., 49, 2010
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3A2L
 | | Crystal structure of DBJA (mutant dbja delta) | | 分子名称: | CHLORIDE ION, GLYCEROL, Haloalkane dehalogenase, ... | | 著者 | Sato, Y, Senda, T. | | 登録日 | 2009-05-23 | | 公開日 | 2010-05-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Enantioselectivity of haloalkane dehalogenases and its modulation by surface loop engineering
Angew.Chem.Int.Ed.Engl., 49, 2010
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3AFI
 | | Crystal structure of DBJA (HIS-DBJA) | | 分子名称: | CHLORIDE ION, Haloalkane dehalogenase | | 著者 | Sato, Y, Senda, T. | | 登録日 | 2010-03-02 | | 公開日 | 2011-01-19 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Enantioselectivity of haloalkane dehalogenases and its modulation by surface loop engineering
Angew.Chem.Int.Ed.Engl., 49, 2010
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3A2N
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6S6E
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8CE0
 | | N-terminal domain of human apolipoprotein E | | 分子名称: | GLYCEROL, Maltodextrin-binding protein,Apolipoprotein E | | 著者 | Marek, M, Nemergut, M. | | 登録日 | 2023-02-01 | | 公開日 | 2023-07-19 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer's Disease drug candidate.
Mol Neurodegener, 18, 2023
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8CDY
 | | N-terminal domain of human apolipoprotein E | | 分子名称: | Maltodextrin-binding protein,Apolipoprotein E | | 著者 | Marek, M, Nemergut, M. | | 登録日 | 2023-02-01 | | 公開日 | 2023-07-19 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer's Disease drug candidate.
Mol Neurodegener, 18, 2023
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4F5Z
 | | Crystal structure of Rhodococcus rhodochrous haloalkane dehalogenase mutant (L95V, A172V). | | 分子名称: | BENZOIC ACID, CHLORIDE ION, Haloalkane dehalogenase | | 著者 | Kulik, D, Kuta-Smatanova, I, Rezacova, P. | | 登録日 | 2012-05-14 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel.
Angew.Chem.Int.Ed.Engl., 52, 2013
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4F60
 | | Crystal structure of Rhodococcus rhodochrous haloalkane dehalogenase mutant (T148L, G171Q, A172V, C176F). | | 分子名称: | FLUORIDE ION, Haloalkane dehalogenase | | 著者 | Plevaka, M, Kuta-Smatanova, I, Rezacova, P. | | 登録日 | 2012-05-14 | | 公開日 | 2013-01-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel.
Angew.Chem.Int.Ed.Engl., 52, 2013
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4E46
 | | Structure of Rhodococcus rhodochrous haloalkane dehalogenase DhaA in complex with 2-propanol | | 分子名称: | ACETATE ION, CHLORIDE ION, Haloalkane dehalogenase, ... | | 著者 | Stsiapanava, A, Chaloupkova, R, Damborsky, J, Kuta Smatanova, I. | | 登録日 | 2012-03-12 | | 公開日 | 2013-03-13 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | | 主引用文献 | Expansion of access tunnels and active-site cavities influence activity of haloalkane dehalogenases in organic cosolvents.
Chembiochem, 14, 2013
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2BFN
 | | The crystal structure of the complex of the haloalkane dehalogenase LinB with the product of dehalogenation reaction 1,2-dichloropropane. | | 分子名称: | (2S)-2,3-DICHLOROPROPAN-1-OL, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Banas, P, Otyepka, M, Jerabek, P, Vevodova, J, Bohac, M, Damborsky, J. | | 登録日 | 2004-12-09 | | 公開日 | 2006-06-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Weak Activity of Haloalkane Dehalogenase Linb with 1,2,3-Trichloropropane Revealed by X-Ray Crystallography and Microcalorimetry
Appl.Environ.Microbiol., 73, 2007
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5LKA
 | | Crystal structure of haloalkane dehalogenase LinB 140A+143L+177W+211L mutant (LinB86) from Sphingobium japonicum UT26 at 1.3 A resolution | | 分子名称: | Haloalkane dehalogenase, THIOCYANATE ION | | 著者 | Degtjarik, O, Rezacova, P, Iermak, I, Chaloupkova, R, Damborsky, J, Kuta Smatanova, I. | | 登録日 | 2016-07-21 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.298 Å) | | 主引用文献 | Engineering a de novo transport tunnel.
Acs Catalysis, 2016
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6XTC
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6XT8
 | | Crystal structure of haloalkane dehalogenase variant DhaA115 domain-swapped dimer type-2 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | | 著者 | Markova, K, Damborsky, J, Marek, M. | | 登録日 | 2020-01-15 | | 公開日 | 2021-01-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Computational Enzyme Stabilization Can Affect Folding Energy Landscapes and Lead to Catalytically Enhanced Domain-Swapped Dimers
Acs Catalysis, 11, 2021
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6YN2
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8AX8
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8AX9
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7OMO
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7OMR
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7OMD
 | | Crystal structure of azacoelenterazine-bound Renilla reniformis luciferase variant RLuc8-D162A | | 分子名称: | 6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-8-(phenylmethyl)-[1,2,4]triazolo[4,3-a]pyrazin-3-one, CHLORIDE ION, Coelenterazine h 2-monooxygenase, ... | | 著者 | Schenkmayerova, A, Janin, Y.L, Marek, M. | | 登録日 | 2021-05-21 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | | 主引用文献 | Catalytic mechanism for Renilla-type luciferases
Nat Catal, 2023
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