6GEB
 
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6GEF
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8C9X
 | | human alpha7 nicotinic receptor in complex with the C4 nanobody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody C4, ... | | 著者 | Prevost, M.S, Barilone, N, Dejean de la Batie, G, Pons, S, Ayme, G, England, P, Gielen, M, Bontems, F, Pehau-Arnaudet, G, Maskos, U, Lafaye, P, Corringer, P.-J. | | 登録日 | 2023-01-23 | | 公開日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | An original potentiating mechanism revealed by the cryo-EM structures of the human alpha 7 nicotinic receptor in complex with nanobodies.
Nat Commun, 14, 2023
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8CI2
 | | human alpha7 nicotinic receptor in complex with the C4 nanobody under sub-saturating conditions | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody C4, ... | | 著者 | Prevost, M.S, Barilone, N, Dejean de la Batie, G, Pons, S, Ayme, G, England, P, Gielen, M, Bontems, F, Pehau-Arnaudet, G, Maskos, U, Lafaye, P, Corringer, P.-J. | | 登録日 | 2023-02-08 | | 公開日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | An original potentiating mechanism revealed by the cryo-EM structures of the human alpha 7 nicotinic receptor in complex with nanobodies.
Nat Commun, 14, 2023
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8CAU
 | | human alpha7 nicotinic receptor in complex with the C4 nanobody and nicotine | | 分子名称: | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Prevost, M.S, Barilone, N, Dejean de la Batie, G, Pons, S, Ayme, G, England, P, Gielen, M, Bontems, F, Pehau-Arnaudet, G, Maskos, U, Lafaye, P, Corringer, P.-J. | | 登録日 | 2023-01-24 | | 公開日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | An original potentiating mechanism revealed by the cryo-EM structures of the human alpha 7 nicotinic receptor in complex with nanobodies.
Nat Commun, 14, 2023
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8CE4
 | | Human alpha7 nicotinic receptor in complex with the E3 nanobody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody E3, ... | | 著者 | Prevost, M.S, Barilone, N, Dejean de la Batie, G, Pons, S, Ayme, G, England, P, Gielen, M, Bontems, F, Pehau-Arnaudet, G, Maskos, U, Lafaye, P, Corringer, P.-J. | | 登録日 | 2023-02-01 | | 公開日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | An original potentiating mechanism revealed by the cryo-EM structures of the human alpha 7 nicotinic receptor in complex with nanobodies.
Nat Commun, 14, 2023
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8CI1
 | | Human alpha7 nicotinic receptor in complex with the E3 nanobody and nicotine | | 分子名称: | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Prevost, M.S, Barilone, N, Dejean de la Batie, G, Pons, S, Ayme, G, England, P, Gielen, M, Bontems, F, Pehau-Arnaudet, G, Maskos, U, Lafaye, P, Corringer, P.-J. | | 登録日 | 2023-02-08 | | 公開日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | An original potentiating mechanism revealed by the cryo-EM structures of the human alpha 7 nicotinic receptor in complex with nanobodies.
Nat Commun, 14, 2023
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5NNY
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3UU4
 | | The GLIC pentameric Ligand-Gated Ion Channel Loop2-21' mutant reduced in the crystal in a locally-closed conformation (LC1 subtype) | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Glr4197 protein | | 著者 | Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. | | 登録日 | 2011-11-28 | | 公開日 | 2012-05-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | A locally closed conformation of a bacterial pentameric proton-gated ion channel.
Nat.Struct.Mol.Biol., 19, 2012
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3UUB
 | | The GLIC pentameric Ligand-Gated Ion Channel Loop2-21' mutant reduced in solution | | 分子名称: | CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. | | 登録日 | 2011-11-28 | | 公開日 | 2012-05-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A locally closed conformation of a bacterial pentameric proton-gated ion channel.
Nat.Struct.Mol.Biol., 19, 2012
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3UU5
 | | The GLIC pentameric Ligand-Gated Ion Channel Loop2-20' mutant reduced in solution | | 分子名称: | CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. | | 登録日 | 2011-11-28 | | 公開日 | 2012-05-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A locally closed conformation of a bacterial pentameric proton-gated ion channel.
Nat.Struct.Mol.Biol., 19, 2012
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3UU3
 | | The GLIC pentameric Ligand-Gated Ion Channel Loop2-20' oxidized mutant in a locally-closed conformation (LC1 subtype) | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, Glr4197 protein | | 著者 | Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. | | 登録日 | 2011-11-28 | | 公開日 | 2012-05-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | A locally closed conformation of a bacterial pentameric proton-gated ion channel.
Nat.Struct.Mol.Biol., 19, 2012
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3UU8
 | | The GLIC pentameric Ligand-Gated Ion Channel Loop2-24' mutant reduced in solution | | 分子名称: | CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. | | 登録日 | 2011-11-28 | | 公開日 | 2012-05-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | A locally closed conformation of a bacterial pentameric proton-gated ion channel.
Nat.Struct.Mol.Biol., 19, 2012
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3UU6
 | | The GLIC pentameric Ligand-Gated Ion Channel Loop2-22' mutant reduced in solution | | 分子名称: | CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. | | 登録日 | 2011-11-28 | | 公開日 | 2012-05-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | | 主引用文献 | A locally closed conformation of a bacterial pentameric proton-gated ion channel.
Nat.Struct.Mol.Biol., 19, 2012
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3TLW
 | | The GLIC pentameric Ligand-Gated Ion Channel Loop2-21' oxidized mutant in a locally-closed conformation (LC2 subtype) | | 分子名称: | CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Glr4197 protein | | 著者 | Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. | | 登録日 | 2011-08-30 | | 公開日 | 2012-05-16 | | 最終更新日 | 2012-06-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A locally closed conformation of a bacterial pentameric proton-gated ion channel.
Nat.Struct.Mol.Biol., 19, 2012
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3TLS
 | | The GLIC pentameric Ligand-Gated Ion Channel E19'P mutant in a locally-closed conformation (LC2 subtype) | | 分子名称: | CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Glr4197 protein | | 著者 | Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. | | 登録日 | 2011-08-30 | | 公開日 | 2012-05-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | A locally closed conformation of a bacterial pentameric proton-gated ion channel.
Nat.Struct.Mol.Biol., 19, 2012
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3TLU
 | | The GLIC pentameric Ligand-Gated Ion Channel Loop2-24' oxidized mutant in a locally-closed conformation (LC1 subtype) | | 分子名称: | CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Glr4197 protein | | 著者 | Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. | | 登録日 | 2011-08-30 | | 公開日 | 2012-05-16 | | 最終更新日 | 2012-06-27 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | A locally closed conformation of a bacterial pentameric proton-gated ion channel.
Nat.Struct.Mol.Biol., 19, 2012
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3TLT
 | | The GLIC pentameric Ligand-Gated Ion Channel H11'F mutant in a locally-closed conformation (LC1 subtype) | | 分子名称: | CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Glr4197 protein | | 著者 | Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. | | 登録日 | 2011-08-30 | | 公開日 | 2012-05-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | A locally closed conformation of a bacterial pentameric proton-gated ion channel.
Nat.Struct.Mol.Biol., 19, 2012
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3TLV
 | | The GLIC pentameric Ligand-Gated Ion Channel Loop2-22' oxidized mutant in a locally-closed conformation (LC3 subtype) | | 分子名称: | CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, Glr4197 protein | | 著者 | Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. | | 登録日 | 2011-08-30 | | 公開日 | 2012-05-16 | | 最終更新日 | 2012-06-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A locally closed conformation of a bacterial pentameric proton-gated ion channel.
Nat.Struct.Mol.Biol., 19, 2012
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