2KQ6
| The structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity | 分子名称: | Polycystin-2 | 著者 | Petri, E.T, Celic, A, Kennedy, S.D, Ehrlich, B.E, Boggon, T.J, Hodsdon, M.E. | 登録日 | 2009-10-28 | 公開日 | 2010-05-12 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activity. Proc.Natl.Acad.Sci.USA, 107, 2010
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8BBS
| Structure of AKR1C3 in complex with a bile acid fused tetrazole inhibitor | 分子名称: | (4~{R})-4-[(1~{R},2~{S},5~{R},6~{R},13~{S},14~{S},17~{R},19~{R})-6,14-dimethyl-17-oxidanyl-7,8,9,10-tetrazapentacyclo[11.8.0.0^{2,6}.0^{7,11}.0^{14,19}]henicosa-8,10-dien-5-yl]pentanoic acid, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Petri, E.T, Skerlova, J, Marinovic, M, Brynda, J, Kugler, M, Skoric, D, Bekic, S, Celic, A.S, Rezacova, P. | 登録日 | 2022-10-14 | 公開日 | 2023-03-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | X-ray structure of human aldo-keto reductase 1C3 in complex with a bile acid fused tetrazole inhibitor: experimental validation, molecular docking and structural analysis. Rsc Med Chem, 14, 2023
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2MHH
| Solution structure of a EF-hand domain from sea urchin polycystin-2 | 分子名称: | Polycystic kidney disease protein 2 | 著者 | Kuo, I.Y, Keeler, C, Corbin, R, Celic, A, Petri, E.T, Hodsdon, M.E, Ehrlich, B.E. | 登録日 | 2013-11-22 | 公開日 | 2014-10-08 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The number and location of EF hand motifs dictates the calcium dependence of polycystin-2 function. Faseb J., 28, 2014
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