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6T9D
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BU of 6t9d by Molmil
Crystal structure of a bispecific DutaFab in complex with human VEGF121
分子名称: VP mat DutaFab VH chain, VP mat DutaFab VL chain, Vascular endothelial growth factor A
著者Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H.
登録日2019-10-28
公開日2020-12-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.905 Å)
主引用文献DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously.
Nat Commun, 12, 2021
6T9E
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BU of 6t9e by Molmil
Crystal structure of a bispecific DutaFab in complex with human PDGF
分子名称: DutaFab mat VH chain, DutaFab mat VL chain, Platelet-derived growth factor subunit B
著者Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H.
登録日2019-10-28
公開日2020-12-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.989 Å)
主引用文献DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously.
Nat Commun, 12, 2021
3TOI
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BU of 3toi by Molmil
Tailoring Enzyme Stability and Exploiting Stability-Trait Linkage by Iterative Truncation and Optimization
分子名称: Ampicillin resistance protein
著者Tam, H.K, Einsle, O.
登録日2011-09-05
公開日2012-05-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Exploring the Molecular Linkage of Protein Stability Traits for Enzyme Optimization by Iterative Truncation and Evolution.
Biochemistry, 51, 2012
7TFB
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BU of 7tfb by Molmil
P. polymyxa GS(14)-Q-GlnR peptide
分子名称: GLUTAMINE, GlnR C-tail peptide, Glutamine synthetase, ...
著者Travis, B.A, Peck, J, Schumacher, M.A.
登録日2022-01-06
公開日2022-06-29
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.28 Å)
主引用文献Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7TF9
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BU of 7tf9 by Molmil
L. monocytogenes GS(14)-Q-GlnR peptide
分子名称: C-tail peptide of Glutamine synthetase repressor, GLUTAMINE, Glutamine synthetase, ...
著者Travis, B.A, Peck, J, Schumacher, M.A.
登録日2022-01-06
公開日2022-06-29
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.61 Å)
主引用文献Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7TFA
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BU of 7tfa by Molmil
P. polymyxa GS(12)-Q-GlnR peptide
分子名称: GLUTAMINE, GlnR C-tail peptide, Glutamine synthetase, ...
著者Travis, B.A, Peck, J, Schumacher, M.A.
登録日2022-01-06
公開日2022-06-29
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.07 Å)
主引用文献Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7TF6
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BU of 7tf6 by Molmil
S. aureus GS(12)-Q-GlnR peptide
分子名称: GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ...
著者Travis, B.A, Peck, J, Schumacher, M.A.
登録日2022-01-06
公開日2022-06-29
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.15 Å)
主引用文献Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7TF7
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BU of 7tf7 by Molmil
S. aureus GS(12) - apo
分子名称: Glutamine synthetase
著者Travis, B.A, Peck, J, Schumacher, M.A.
登録日2022-01-06
公開日2022-06-29
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.13 Å)
主引用文献Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7TFE
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BU of 7tfe by Molmil
L. monocytogenes GS(12) - apo
分子名称: Glutamine synthetase, MAGNESIUM ION
著者Travis, B.A, Peck, J, Schumacher, M.A.
登録日2022-01-06
公開日2022-06-29
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7TFC
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BU of 7tfc by Molmil
B. subtilis GS(14)-Q-GlnR peptide
分子名称: GLUTAMINE, GlnR C-tail peptide, Glutamine synthetase, ...
著者Travis, B.A, Peck, J, Schumacher, M.A.
登録日2022-01-06
公開日2022-06-29
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (1.96 Å)
主引用文献Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7TFD
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BU of 7tfd by Molmil
P. polymyxa GS(12) - apo
分子名称: Glutamine synthetase, MAGNESIUM ION
著者Travis, B.A, Peck, J, Schumacher, M.A.
登録日2022-01-06
公開日2022-06-29
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
3L0R
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BU of 3l0r by Molmil
Crystal Structure of Salivary Cystatin from the Soft Tick Ornithodoros moubata
分子名称: CHLORIDE ION, Cystatin-2, GLYCEROL
著者Rezacova, P, Brynda, J, Andersen, J.F, Salat, J, Kovarova, Z, Mares, M.
登録日2009-12-10
公開日2010-06-30
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure and functional characterization of an immunomodulatory salivary cystatin from the soft tick Ornithodoros moubata
Biochem.J., 429, 2010
5O46
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BU of 5o46 by Molmil
Crystal structure of Iristatin, a secreted salivary cystatin from the hard tick Ixodes ricinus
分子名称: GLYCEROL, Iristatin
著者Busa, M, Rezacova, P, Kotal, J, Kotsyfakis, M, Mares, M.
登録日2017-05-26
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献The structure and function of Iristatin, a novel immunosuppressive tick salivary cystatin.
Cell.Mol.Life Sci., 76, 2019
3NDA
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BU of 3nda by Molmil
Crystal structure of serpin from tick Ixodes ricinus
分子名称: PENTAETHYLENE GLYCOL, Serpin-2
著者Rezacova, P, Kovarova, Z, Chmelar, J, Mares, M.
登録日2010-06-07
公開日2010-10-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation.
Blood, 117, 2011
4C7N
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BU of 4c7n by Molmil
Crystal Structure of the synthetic peptide iM10 in complex with the coiled-coil region of MITF
分子名称: MERCURY (II) ION, MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR, SYNTHETIC ALPHA-HELIX, ...
著者Wohlwend, D, Gerhardt, S, Kuekenshoener, T, Einsle, O.
登録日2013-09-23
公開日2014-04-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Improving Coiled Coil Stability While Maintaining Specificity by a Bacterial Hitchhiker Selection System.
J.Struct.Biol., 186, 2014

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件を2024-07-17に公開中

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