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2XDA
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STRUCTURE OF HELICOBACTER PYLORI TYPE II DEHYDROQUINASE IN COMPLEX WITH INHIBITOR COMPOUND (4R,6R,7S)-2-(2-Cyclopropyl)ethyl-4,6,7- trihydroxy-4,5,6,7-tetrahydrobenzo(b)thiophene-4-carboxylic acid
分子名称: (4R,6R,7S)-2-(2-CYCLOPROPYLETHYL)-4,6,7-TRIHYDROXY-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-4-CARBOXYLIC ACID, 3-DEHYDROQUINATE DEHYDRATASE
著者Paz, S, Tizon, L, Otero, J.M, Llamas-Saiz, A.L, Fox, G.C, van Raaij, M.J, Lamb, H, Hawkins, A.R, Castedo, L, Gonzalez-Bello, C.
登録日2010-04-30
公開日2010-11-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Tetrahydrobenzothiophene derivatives: conformationally restricted inhibitors of type II dehydroquinase.
ChemMedChem, 6, 2011
2XD9
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STRUCTURE OF HELICOBACTER PYLORI TYPE II DEHYDROQUINASE IN COMPLEX WITH INHIBITOR COMPOUND (4R,6R,7S)-4,6,7-Trihydroxy-2-((E)-prop-1- enyl)-4,5,6,7-tetrahydrobenzo(b)thiophene-4-carboxylic acid
分子名称: (4R,6R,7S)-4,6,7-TRIHYDROXY-2-[(1E)-PROP-1-EN-1-YL]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-4-CARBOXYLIC ACID, 3-DEHYDROQUINATE DEHYDRATASE
著者Paz, S, Tizon, L, Otero, J.M, Llamas-Saiz, A.L, Fox, G.C, van Raaij, M.J, Lamb, H, Hawkins, A.R, Lapthorn, A.J, Castedo, L, Gonzalez-Bello, C.
登録日2010-04-30
公開日2010-11-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Tetrahydrobenzothiophene derivatives: conformationally restricted inhibitors of type II dehydroquinase.
ChemMedChem, 6, 2011
6ZN3
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Plasmodium facliparum glideosome trimeric sub-complex
分子名称: Myosin A tail domain interacting protein, Myosin essential light chain ELC, Myosin-A
著者Pazicky, S, Loew, C.
登録日2020-07-06
公開日2020-10-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural role of essential light chains in the apicomplexan glideosome.
Commun Biol, 3, 2020
7OXI
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BU of 7oxi by Molmil
ttSlyD with W4A pseudo-wild-type S2 peptide
分子名称: 30S ribosomal protein S2, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase
著者Pazicky, S, Lei, J, Loew, C.
登録日2021-06-22
公開日2022-03-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Impact of distant peptide substrate residues on enzymatic activity of SlyD.
Cell.Mol.Life Sci., 79, 2022
7OXG
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ttSlyD FKBP domain with M8A pseudo-wild-type S2 peptide
分子名称: 30S ribosomal protein S2, CHLORIDE ION, IMIDAZOLE, ...
著者Pazicky, S, Lei, J, Loew, C.
登録日2021-06-22
公開日2022-03-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Impact of distant peptide substrate residues on enzymatic activity of SlyD.
Cell.Mol.Life Sci., 79, 2022
7OXH
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BU of 7oxh by Molmil
ttSlyD with pseudo-wild-type S2 peptide
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 30S ribosomal protein S2, CHLORIDE ION, ...
著者Pazicky, S, Lei, J, Loew, C.
登録日2021-06-22
公開日2022-03-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Impact of distant peptide substrate residues on enzymatic activity of SlyD.
Cell.Mol.Life Sci., 79, 2022
7OXK
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ttSlyD with W4K pseudo-wild-type S2 peptide
分子名称: 30S ribosomal protein S2, Peptidyl-prolyl cis-trans isomerase
著者Pazicky, S, Lei, J, Loew, C.
登録日2021-06-22
公開日2022-03-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Impact of distant peptide substrate residues on enzymatic activity of SlyD.
Cell.Mol.Life Sci., 79, 2022
7OXJ
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BU of 7oxj by Molmil
ttSlyD with M8A pseudo-wild-type S2 peptide
分子名称: 30S ribosomal protein S2, CHLORIDE ION, Fragment of 30S ribosomal protein S2 peptide, ...
著者Pazicky, S, Lei, J, Loew, C.
登録日2021-06-22
公開日2022-03-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Impact of distant peptide substrate residues on enzymatic activity of SlyD.
Cell.Mol.Life Sci., 79, 2022
6TJ7
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BU of 6tj7 by Molmil
T. gondii myosin A trimeric complex
分子名称: 1,3-PROPANDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Pazicky, S, Loew, C.
登録日2019-11-25
公開日2020-10-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural role of essential light chains in the apicomplexan glideosome.
Commun Biol, 3, 2020
6TJ6
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BU of 6tj6 by Molmil
T. gondii myosin A trimeric complex with ELC1, calcium-free
分子名称: Calmodulin, putative, IMIDAZOLE, ...
著者Pazicky, S, Loew, C.
登録日2019-11-25
公開日2020-10-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural role of essential light chains in the apicomplexan glideosome.
Commun Biol, 3, 2020
6TJ5
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T. gondii myosin A trimeric complex with ELC1
分子名称: CALCIUM ION, CHLORIDE ION, Calmodulin, ...
著者Pazicky, S, Loew, C.
登録日2019-11-25
公開日2020-10-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.394 Å)
主引用文献Structural role of essential light chains in the apicomplexan glideosome.
Commun Biol, 3, 2020
6TJ4
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BU of 6tj4 by Molmil
P. falciparum essential light chain, N-terminal domain
分子名称: PfELC
著者Pazicky, S, Loew, C.
登録日2019-11-25
公開日2020-10-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural role of essential light chains in the apicomplexan glideosome.
Commun Biol, 3, 2020
6TJ3
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BU of 6tj3 by Molmil
P. falciparum essential light chain, N-terminal domain
分子名称: PfELC
著者Weininger, U, Pazicky, S, Loew, C.
登録日2019-11-25
公開日2020-10-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural role of essential light chains in the apicomplexan glideosome.
Commun Biol, 3, 2020
8CXK
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BU of 8cxk by Molmil
Structure of the C. elegans HIM-3 R93Y mutant
分子名称: HORMA domain-containing protein
著者Ego, K.M, Russo, A, Giacopazzi, S, Deshong, A, Menon, M, Ortiz, V, Bhalla, N, Corbett, K.D.
登録日2022-05-21
公開日2023-05-17
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The conserved AAA ATPase PCH-2 distributes its regulation of meiotic prophase events through multiple meiotic HORMADs in C. elegans.
Plos Genet., 19, 2023
2B0S
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BU of 2b0s by Molmil
Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with MN peptide
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, Fab 2219, ...
著者Stanfield, R.L, Gorny, M.K, Zolla-Pazner, S, Wilson, I.A.
登録日2005-09-14
公開日2006-07-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity.
J.Virol., 80, 2006
2B1H
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BU of 2b1h by Molmil
Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with UG29 peptide
分子名称: Fab 2219, heavy chain, light chain, ...
著者Stanfield, R.L, Gorny, M.K, Zolla-Pazner, S, Wilson, I.A.
登録日2005-09-15
公開日2006-07-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity.
J.Virol., 80, 2006
2B1A
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BU of 2b1a by Molmil
Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with UG1033 peptide
分子名称: Fab 2219, heavy chain, light chain, ...
著者Stanfield, R.L, Gorny, M.K, Zolla-Pazner, S, Wilson, I.A.
登録日2005-09-15
公開日2006-07-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.348 Å)
主引用文献Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity.
J.Virol., 80, 2006
1U6V
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BU of 1u6v by Molmil
NMR structure of a V3 (IIIB isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody
分子名称: V3 peptide
著者Rosen, O, Chill, J, Sharon, M, Kessler, N, Mester, B, Zolla-Pazner, S, Anglister, J.
登録日2004-08-02
公開日2005-04-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Induced fit in HIV-neutralizing antibody complexes: evidence for alternative conformations of the gp120 V3 loop and the molecular basis for broad neutralization.
Biochemistry, 44, 2005
1U6U
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BU of 1u6u by Molmil
NMR structure of a V3 (IIIB isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody
分子名称: V3 peptide
著者Rosen, O, Chill, J, Sharon, M, Kessler, N, Mester, B, Zolla-Pazner, S, Anglister, J.
登録日2004-08-02
公開日2005-04-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Induced fit in HIV-neutralizing antibody complexes: evidence for alternative conformations of the gp120 V3 loop and the molecular basis for broad neutralization.
Biochemistry, 44, 2005
1NIZ
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BU of 1niz by Molmil
NMR structure of a V3 (MN isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody
分子名称: Exterior membrane glycoprotein(GP120)
著者Sharon, M, Kessler, N, Levy, R, Zolla-Pazner, S, Gorlach, M, Anglister, J.
登録日2002-12-30
公開日2003-02-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Alternative Conformations of HIV-1 V3 Loops Mimic beta Hairpins in Chemokines, Suggesting a Mechanism for Coreceptor Selectivity.
Structure, 11, 2003
6YJP
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BU of 6yjp by Molmil
Crystal structure of a complex between glycosylated NKp30 and its deglycosylated tumour ligand B7-H6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Natural cytotoxicity triggering receptor 3, Natural cytotoxicity triggering receptor 3 ligand 1
著者Skalova, T, Dohnalek, J, Skorepa, O, Kalouskova, B, Pazicky, S, Blaha, J, Vanek, O.
登録日2020-04-04
公開日2020-07-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Natural Killer Cell Activation Receptor NKp30 Oligomerization Depends on Its N -Glycosylation.
Cancers (Basel), 12, 2020
1Q1J
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Crystal Structure Analysis of anti-HIV-1 Fab 447-52D in complex with V3 peptide
分子名称: Fab 447-52D, heavy chain, light chain, ...
著者Stanfield, R.L, Gorny, M.K, Williams, C, Zolla-Pazner, S, Wilson, I.A.
登録日2003-07-21
公開日2004-02-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural rationale for the broad neutralization of HIV-1 by human monoclonal antibody 447-52D.
Structure, 12, 2004
1NJ0
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BU of 1nj0 by Molmil
NMR structure of a V3 (MN isolate) peptide bound to 447-52D, a human HIV-1 neutralizing antibody
分子名称: Exterior membrane glycoprotein(GP120)
著者Sharon, M, Kessler, N, Levy, R, Zolla-Pazner, S, Gorlach, M, Anglister, J.
登録日2002-12-30
公開日2003-02-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Alternative Conformations of HIV-1 V3 Loops Mimic beta Hairpins in Chemokines, Suggesting a Mechanism for Coreceptor Selectivity.
Structure, 11, 2003
3PIQ
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BU of 3piq by Molmil
Crystal structure of human 2909 Fab, a quaternary structure-specific antibody against HIV-1
分子名称: Human monoclonal antibody 2909 Fab heavy chain, Human monoclonal antibody 2909 Fab light chain
著者Changela, A, Gorny, M.K, Zolla-Pazner, S, Kwong, P.D.
登録日2010-11-07
公開日2011-01-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.325 Å)
主引用文献Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1.
J.Virol., 85, 2011
3P30
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crystal structure of the cluster II Fab 1281 in complex with HIV-1 gp41 ectodomain
分子名称: 1281 Fab heavy chain, 1281 Fab light chain, HIV-1 gp41
著者Frey, G, Chen, J, Rits-Volloch, S, Freeman, M.M, Zolla-Pazner, S, Chen, B.
登録日2010-10-04
公開日2010-11-17
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies.
Nat.Struct.Mol.Biol., 17, 2010

 

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