6K1Q
 
 | | Human endothelin receptor type-B in complex with inverse agonist IRL2500 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2~{S})-2-[[(2~{R})-2-[(3,5-dimethylphenyl)carbonyl-methyl-amino]-3-(4-phenylphenyl)propanoyl]amino]-3-(1~{H}-indol-3-yl)propanoic acid, Endothelin B receptor,Endolysin,Endothelin B receptor, ... | | 著者 | Nagiri, C, Shihoya, W, Nureki, O. | | 登録日 | 2019-05-11 | | 公開日 | 2019-07-17 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of human endothelin ETBreceptor in complex with peptide inverse agonist IRL2500.
Commun Biol, 2, 2019
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7XJH
 | | Isoproterenol-activated dog beta3 adrenergic receptor | | 分子名称: | Beta-3 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Shihoya, W, Nureki, O. | | 登録日 | 2022-04-18 | | 公開日 | 2022-05-04 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structure of the beta 3-adrenergic receptor reveals the molecular basis of subtype selectivity.
Mol.Cell, 81, 2021
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7DH5
 | | Dog beta3 adrenergic receptor bound to mirabegron in complex with a miniGs heterotrimer | | 分子名称: | 2-(2-azanyl-1,3-thiazol-4-yl)-N-[4-[2-[[(2R)-2-oxidanyl-2-phenyl-ethyl]amino]ethyl]phenyl]ethanamide, Beta-3 adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Shihoya, W, Yamashita, K, Nureki, O. | | 登録日 | 2020-11-12 | | 公開日 | 2021-08-04 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | Cryo-EM structure of the beta 3-adrenergic receptor reveals the molecular basis of subtype selectivity.
Mol.Cell, 81, 2021
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8YH0
 | | A3R-Gi complex bound to NECA | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, HA tag,Adenosine receptor A3,LgBiT,eGFP chimera, ... | | 著者 | Oshima, H.S, Shihoya, W, Nureki, O. | | 登録日 | 2024-02-27 | | 公開日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | | 主引用文献 | Structural insight into the agonist selectivity and structure-based engineering of the adenosine A3 receptor
To Be Published
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8YH3
 | | A3R-Gi complex bound to m6A | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,Guanine nucleotide-binding protein G(i) subunit alpha-1 chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Hemagglutinin,Adenosine receptor A3,GFP chimera, ... | | 著者 | Oshima, H.S, Shihoya, W, Nureki, O. | | 登録日 | 2024-02-27 | | 公開日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural insights into the agonist selectivity and structure-based engineering of the adenosine A3 receptor
To Be Published
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8YH6
 | | A3R-Gi complex bound to namodenoson | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,Guanine nucleotide-binding protein G(i) subunit alpha-1 chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Hemagglutinin,Adenosine receptor A3,GFP chimera, ... | | 著者 | Oshima, H.S, Shihoya, W, Nureki, O. | | 登録日 | 2024-02-27 | | 公開日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | Structural insights into the agonist selectivity and structure-based engineering of the adenosine A3 receptor
To Be Published
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8YH2
 | | A3R-Gi complex bound to adenosine | | 分子名称: | ADENOSINE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,Guanine nucleotide-binding protein G(i) subunit alpha-1 chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Oshima, H.S, Shihoya, W, Nureki, O. | | 登録日 | 2024-02-27 | | 公開日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Structural insights into the agonist selectivity and structure-based engineering of the adenosine A3 receptor
To Be Published
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8YH5
 | | A3R-Gi complex bound to i6A | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2,Guanine nucleotide-binding protein G(i) subunit alpha-1 chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Hemagglutinin,Adenosine receptor A3,GFP chimera, ... | | 著者 | Oshima, H.S, Shihoya, W, Nureki, O. | | 登録日 | 2024-02-27 | | 公開日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | | 主引用文献 | Structural insights into the agonist selectivity and structure-based engineering of the adenosine A3 receptor
To Be Published
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