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Triazolopyridine-based Inhibitor of Janus Kinase 2
分子名称:	8-(4-methylsulfonylphenyl)-N-(4-morpholin-4-ylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine, SULFATE ION, TYROSINE-PROTEIN KINASE JAK2
著者	Dugan, B.J, Gingrich, D.E, Mesaros, E.F, Milkiewicz, K.L, Curry, M.A, Zulli, A.L, Dobrzanski, P, Serdikoff, C, Jan, M, Angeles, T.S, Albom, M.S, Mason, J.L, Aimone, L.D, Meyer, S.L, Huang, Z, Wells-Knecht, K.J, Ator, M.A, Ruggeri, B.A, Dorsey, B.D.
登録日	2012-04-16
公開日	2012-04-25
最終更新日	2019-05-08
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	A Selective, Orally Bioavailable 1,2,4-Triazolo[1,5-A]Pyridine-Based Inhibitor of Janus Kinase 2 for Use in Anticancer Therapy: Discovery of Cep-33779. J.Med.Chem., 55, 2012

X-ray Structure of FXa in complex with 7-fluoroindazole
分子名称:	1-(3-amino-1,2-benzisoxazol-5-yl)-6-(4-{2-[(dimethylamino)methyl]-1H-imidazol-1-yl}-2-fluorophenyl)-7-fluoro-1H-indazole-3-carboxamide, Coagulation factor X
著者	Abad, M.C.
登録日	2007-09-14
公開日	2008-01-29
最終更新日	2021-10-20
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	7-fluoroindazoles as potent and selective inhibitors of factor xa. J.Med.Chem., 51, 2008

Structure of human MDM2 in complex with an optimized p53 peptide
分子名称:	SULFATE ION, Ubiquitin-protein ligase E3 Mdm2, optimized p53 peptide
著者	Grasberger, B.L, Schubert, C, Koblish, H.K, Carver, T.E, Franks, C.F, Zhao, S.Y, Lu, T, LaFrance, L.V, Parks, D.J.
登録日	2004-04-29
公開日	2005-02-08
最終更新日	2023-08-23
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells J.Med.Chem., 48, 2005