4AE4
| The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a novel SOUBA domain | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, POTASSIUM ION, ... | 著者 | Agromayor, M, Soler, N, Caballe, A, Kueck, T, Freund, S.M, Allen, M.D, Bycroft, M, Perisic, O, Ye, Y, McDonald, B, Scheel, H, Hofmann, K, Neil, S.J.D, Martin-Serrano, J, Williams, R.L. | 登録日 | 2012-01-06 | 公開日 | 2012-03-21 | 最終更新日 | 2018-02-28 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain. Structure, 20, 2012
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2WHV
| CRYSTAL STRUCTURE OF MOUSE CADHERIN-23 EC1-2 (ALL CATION BINDING SITES OCCUPIED BY CALCIUM) | 分子名称: | CADHERIN-23, CALCIUM ION, CHLORIDE ION, ... | 著者 | Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. | 登録日 | 2009-05-07 | 公開日 | 2010-04-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Structural Determinants of Cadherin-23 Function in Hearing and Deafness. Neuron, 66, 2010
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2WCP
| CRYSTAL STRUCTURE OF MOUSE CADHERIN-23 EC1-2 | 分子名称: | CADHERIN-23, CALCIUM ION, CHLORIDE ION, ... | 著者 | Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. | 登録日 | 2009-03-13 | 公開日 | 2010-04-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Structural Determinants of Cadherin-23 Function in Hearing and Deafness. Neuron, 66, 2010
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2WBX
| Crystal structure of mouse cadherin-23 EC1 | 分子名称: | CADHERIN-23, CALCIUM ION | 著者 | Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. | 登録日 | 2009-03-05 | 公開日 | 2010-04-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural Determinants of Cadherin-23 Function in Hearing and Deafness. Neuron, 66, 2010
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2WD0
| CRYSTAL STRUCTURE OF NONSYNDROMIC DEAFNESS (DFNB12) ASSOCIATED MUTANT D124G OF MOUSE CADHERIN-23 EC1-2 | 分子名称: | CADHERIN-23, CALCIUM ION, CHLORIDE ION, ... | 著者 | Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. | 登録日 | 2009-03-18 | 公開日 | 2010-04-21 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Structural Determinants of Cadherin-23 Function in Hearing and Deafness. Neuron, 66, 2010
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4AQE
| CRYSTAL STRUCTURE OF DEAFNESS ASSOCIATED MUTANT MOUSE CADHERIN-23 EC1- 2S70P AND PROTOCADHERIN-15 EC1-2 FORM I | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CADHERIN-23, CALCIUM ION, ... | 著者 | Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. | 登録日 | 2012-04-16 | 公開日 | 2012-11-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Structure of a Force-Conveying Cadherin Bond Essential for Inner-Ear Mechanotransduction Nature, 492, 2012
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4APX
| CRYSTAL STRUCTURE OF MOUSE CADHERIN-23 EC1-2 AND PROTOCADHERIN-15 EC1- 2 FORM I | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CADHERIN-23, CALCIUM ION, ... | 著者 | Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. | 登録日 | 2012-04-07 | 公開日 | 2012-11-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structure of a Force-Conveying Cadherin Bond Essential for Inner-Ear Mechanotransduction Nature, 492, 2012
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4AQA
| CRYSTAL STRUCTURE OF DEAFNESS ASSOCIATED MUTANT MOUSE CADHERIN-23 EC1- 2D124G AND PROTOCADHERIN-15 EC1-2 FORM I | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CADHERIN-23, CALCIUM ION, ... | 著者 | Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. | 登録日 | 2012-04-15 | 公開日 | 2012-11-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structure of a Force-Conveying Cadherin Bond Essential for Inner-Ear Mechanotransduction Nature, 492, 2012
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4AXW
| CRYSTAL STRUCTURE OF MOUSE CADHERIN-23 EC1-2 AND PROTOCADHERIN-15 EC1- 2, FORM I 2.2A. | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CADHERIN-23, CALCIUM ION, ... | 著者 | Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. | 登録日 | 2012-06-14 | 公開日 | 2012-11-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Structure of a Force-Conveying Cadherin Bond Essential for Inner-Ear Mechanotransduction Nature, 492, 2012
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4AQ8
| CRYSTAL STRUCTURE OF MOUSE CADHERIN-23 EC1-2 AND PROTOCADHERIN-15 EC1- 2 FORM II | 分子名称: | CADHERIN-23, CALCIUM ION, PROTOCADHERIN-15 | 著者 | Sotomayor, M, Weihofen, W, Gaudet, R, Corey, D.P. | 登録日 | 2012-04-13 | 公開日 | 2012-11-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Structure of a Force-Conveying Cadherin Bond Essential for Inner-Ear Mechanotransduction Nature, 492, 2012
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8V1O
| Crystal structure of IRAK4 kinase domain with compound 4 | 分子名称: | CHLORIDE ION, GLYCEROL, Interleukin-1 receptor-associated kinase 4, ... | 著者 | Weiss, M.M, Zheng, X, Browne, C.M, Campbell, V, Chen, D, Enerson, B, Fei, X, Huang, X, Klaus, C.R, Li, H, Mayo, M, McDonald, A.A, Paul, A, Sharma, K, Shi, Y, Slavin, A, Walter, D.M, Yuan, K, Zhang, Y, Zhu, X, Kelleher, J, Ji, N, Walker, D, Mainolfi, N. | 登録日 | 2023-11-21 | 公開日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | 主引用文献 | Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma J.Med.Chem., 2024
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8V2L
| Crystal structure of IRAK4 kinase domain with compound 8 | 分子名称: | 1,2-ETHANEDIOL, Interleukin-1 receptor-associated kinase 4, N-{2-[4-(hydroxymethyl)phenyl]-6-(2-hydroxypropan-2-yl)-2H-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide | 著者 | Weiss, M.M, Zheng, X, Browne, C.M, Campbell, V, Chen, D, Enerson, B, Fei, X, Huang, X, Klaus, C.R, Li, H, Mayo, M, McDonald, A.A, Paul, A, Sharma, K, Shi, Y, Slavin, A, Walter, D.M, Yuan, K, Zhang, Y, Zhu, X, Kelleher, J, Ji, N, Walker, D, Mainolfi, N. | 登録日 | 2023-11-22 | 公開日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma J.Med.Chem., 2024
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8V2F
| Crystal structure of IRAK4 kinase domain with compound 9 | 分子名称: | CHLORIDE ION, GLYCEROL, Interleukin-1 receptor-associated kinase 4, ... | 著者 | Weiss, M.M, Zheng, X, Browne, C.M, Campbell, V, Chen, D, Enerson, B, Fei, X, Huang, X, Klaus, C.R, Li, H, Mayo, M, McDonald, A.A, Paul, A, Sharma, K, Shi, Y, Slavin, A, Walter, D.M, Yuan, K, Zhang, Y, Zhu, X, Kelleher, J, Ji, N, Walker, D, Mainolfi, N. | 登録日 | 2023-11-22 | 公開日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Discovery of KT-413, a Targeted Protein Degrader of IRAK4 and IMiD Substrates Targeting MYD88 Mutant Diffuse Large B-Cell Lymphoma J.Med.Chem., 2024
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4WZX
| ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins | 分子名称: | COBALT (II) ION, IST1 homolog, SULFATE ION, ... | 著者 | Caballe, A, Wenzel, D.M, Agromayor, M, Alam, S.L, Skalicky, J.J, Kloc, M, Carlton, J.G, Labrador, L, Sundquist, W.I, Martin-Serrano, J. | 登録日 | 2014-11-20 | 公開日 | 2015-06-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.3859 Å) | 主引用文献 | ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins. Elife, 4, 2015
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5WJ8
| Crystal Structure of Human Cadherin-23 EC13-14 | 分子名称: | CALCIUM ION, CHLORIDE ION, Cadherin-23, ... | 著者 | Velez-Cortes, F, Conghui, C, De-la-Torre, P, Sotomayor, M. | 登録日 | 2017-07-21 | 公開日 | 2018-07-04 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness. Structure, 26, 2018
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6NW1
| Crystal Structure Desulfovibrio desulfuricans Nickel-Substituted Rubredoxin V37N | 分子名称: | NICKEL (II) ION, Rubredoxin | 著者 | Slater, J.W, Marguet, S.C, Gray, M.E, Sotomayor, M, Shafaat, H.S. | 登録日 | 2019-02-05 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | The Power of the Secondary Sphere: Modulating Hydrogenase Activity in Nickel-Substituted Rubredoxin Acs Catalysis, 2019
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5WJM
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6ULM
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7N86
| Crystal Structure of Human Protocadherin-24 EC1-2 Form II | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Modak, D, Gray, M.E, Sotomayor, M. | 登録日 | 2021-06-13 | 公開日 | 2021-09-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.175 Å) | 主引用文献 | Heterophilic and homophilic cadherin interactions in intestinal intermicrovillar links are species dependent. Plos Biol., 19, 2021
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7N4P
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7U71
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7UQU
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2YMB
| Structures of MITD1 | 分子名称: | CHARGED MULTIVESICULAR BODY PROTEIN 1A, MIT DOMAIN-CONTAINING PROTEIN 1 | 著者 | Hadders, M.A, Agromayor, M, Obita, T, Perisic, O, Caballe, A, Kloc, M, Lamers, M.H, Williams, R.L, Martin-Serrano, J. | 登録日 | 2012-10-08 | 公開日 | 2012-10-24 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.404 Å) | 主引用文献 | Escrt-III Binding Protein Mitd1 is Involved in Cytokinesis and Has an Unanticipated Pld Fold that Binds Membranes. Proc.Natl.Acad.Sci.USA, 109, 2012
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6OAE
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4XHZ
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