6TBB
 
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6TBC
 | | Crystal structure of S. aureus FabI in complex with NADPH and kalimantacin B | | 分子名称: | (2~{E},5~{R},10~{E},12~{E},15~{S},19~{R})-20-[[(2~{R},3~{R})-3-aminocarbonyloxy-2-methyl-butanoyl]amino]-3,5,15-trimethyl-7-methylidene-19-oxidanyl-17-oxidanylidene-icosa-2,10,12-trienoic acid, Enoyl-[acyl-carrier-protein] reductase [NADPH], NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Fage, C.D, Masschelein, J. | | 登録日 | 2019-11-01 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in Staphylococcus aureus by Targeting the Enoyl-Acyl Carrier Protein Binding Site of FabI.
Angew.Chem.Int.Ed.Engl., 59, 2020
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5MTI
 | | Bamb_5917 Acyl-Carrier Protein | | 分子名称: | Phosphopantetheine-binding protein | | 著者 | Gallo, A, Kosol, S, Griffiths, D, Masschelein, J, Alkhalaf, L, Smith, H, Valentic, T, Tsai, S, Challis, G, Lewandowski, J.R. | | 登録日 | 2017-01-09 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for chain release from the enacyloxin polyketide synthase
Nat.Chem., 2019
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6CGO
 | | Molecular basis for condensation domain-mediated chain release from the enacyloxin polyketide synthase | | 分子名称: | Condensation domain protein, PHOSPHATE ION | | 著者 | Valentic, T.R, Tsai, S.C, Challis, G.L, Lewandowski, J.R, Kosol, S, Gallo, A, Griffiths, D, Masschelein, J.L, Jenner, M, De los Santos, E. | | 登録日 | 2018-02-20 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for chain release from the enacyloxin polyketide synthase.
Nat.Chem., 11, 2019
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2L22
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