3ODJ
| Crystal structure of H. influenzae rhomboid GlpG with disordered loop 4, helix 5 and loop 5 | 分子名称: | Rhomboid protease glpG | 著者 | Brooks, C.L, Lazareno-Saez, C, Lamoureux, J.S, Mak, M.W, Lemieux, M.J. | 登録日 | 2010-08-11 | 公開日 | 2011-02-23 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Insights into Substrate Gating in H. influenzae Rhomboid. J.Mol.Biol., 407, 2011
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3UAQ
| Crystal Structure of the N-lobe Domain of Lactoferrin Binding Protein B (LbpB) of Moraxella bovis | 分子名称: | LbpB B-lobe | 著者 | Arutyunova, E, Brooks, C.L, Beddeck, A, Mak, M.W, Schryvers, A.B, Lemieux, M.J. | 登録日 | 2011-10-21 | 公開日 | 2012-03-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.9318 Å) | 主引用文献 | Crystal structure of the N-lobe of lactoferrin binding protein B from Moraxella bovis(1). Biochem.Cell Biol., 90, 2012
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4YTH
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4YTF
| Discovery of VX-509 (Decernotinib): A Potent and Selective Janus kinase (JAK) 3 Inhibitor for the Treatment of Autoimmune Diseases | 分子名称: | N~2~-[2-(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoropyrimidin-4-yl]-N-(2,2,2-trifluoroethyl)-L-alaninamide, Tyrosine-protein kinase JAK2 | 著者 | Farmer, L, Ledeboer, M.W, Zuccola, H.J. | 登録日 | 2015-03-17 | 公開日 | 2015-08-12 | 最終更新日 | 2015-10-07 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases. J.Med.Chem., 58, 2015
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4YTC
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4YTI
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4P1U
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4NCM
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4NCE
| Influenza polymerase basic protein 2 (PB2) bound to 7-methyl-GTP | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, 9,10-dioxo-9,10-dihydroanthracene-2,6-disulfonic acid, Polymerase basic protein 2 | 著者 | Jacobs, M.D. | 登録日 | 2013-10-24 | 公開日 | 2014-07-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Discovery of a Novel, First-in-Class, Orally Bioavailable Azaindole Inhibitor (VX-787) of Influenza PB2. J.Med.Chem., 57, 2014
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