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2A3V
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BU of 2a3v by Molmil
Structural basis for broad DNA-specificity in integron recombination
分子名称: DNA (31-MER), DNA (34-MER), site-specific recombinase IntI4
著者MacDonald, D, Demarre, G, Bouvier, M, Mazel, D, Gopaul, D.N.
登録日2005-06-27
公開日2006-05-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for broad DNA-specificity in integron recombination.
Nature, 440, 2006
1FZX
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BU of 1fzx by Molmil
NMR SOLUTION STRUCTURE OF THE DNA DODECAMER GGCAAAAAACGG
分子名称: 5'-D(*CP*CP*GP*TP*TP*TP*TP*TP*TP*GP*CP*C)-3', 5'-D(*GP*GP*CP*AP*AP*AP*AP*AP*AP*CP*GP*G)-3'
著者MacDonald, D, Herbert, K, Zhang, X, Pologruto, T, Lu, P.
登録日2000-10-04
公開日2001-03-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of an A-tract DNA bend.
J.Mol.Biol., 306, 2001
1G14
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BU of 1g14 by Molmil
NMR SOLUTION STRUCTURE OF THE DNA DODECAMER GGCAAGAAACGG
分子名称: 5'-D(*CP*CP*GP*TP*TP*TP*CP*TP*TP*GP*CP*C)-3', 5'-D(*GP*GP*CP*AP*AP*GP*AP*AP*AP*CP*GP*G)-3'
著者MacDonald, D, Herbert, K, Zhang, X, Pologruto, T, Lu, P.
登録日2000-10-10
公開日2001-03-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of an A-tract DNA bend.
J.Mol.Biol., 306, 2001
2FM5
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BU of 2fm5 by Molmil
Crystal structure of PDE4D2 in complex with inhibitor L-869299
分子名称: (R)-3-(2-(3-CYCLOPROPOXY-4-(DIFLUOROMETHOXY)PHENYL)-2-(5-(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPAN-2-YL)THIAZOL-2-YL)ETHYL)PYRIDINE 1-OXIDE, MAGNESIUM ION, ZINC ION, ...
著者Huai, Q, Sun, Y, Wang, H, Macdonald, D, Aspiotis, R, Robinson, H, Huang, Z, Ke, H.
登録日2006-01-07
公開日2006-03-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Enantiomer Discrimination Illustrated by the High Resolution Crystal Structures of Type 4 Phosphodiesterase
J.Med.Chem., 49, 2006
2FM0
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BU of 2fm0 by Molmil
Crystal structure of PDE4D in complex with L-869298
分子名称: (S)-3-(2-(3-CYCLOPROPOXY-4-(DIFLUOROMETHOXY)PHENYL)-2-(5-(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPAN-2-YL)THIAZOL-2-YL)ETHY L)PYRIDINE 1-OXIDE, MAGNESIUM ION, ZINC ION, ...
著者Huai, Q, Sun, Y, Wang, H, Macdonald, D, Aspiotis, R, Robinson, H, Huang, Z, Ke, H.
登録日2006-01-06
公開日2006-03-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Enantiomer Discrimination Illustrated by the High Resolution Crystal Structures of Type 4 Phosphodiesterase
J.Med.Chem., 49, 2006
6PYD
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BU of 6pyd by Molmil
Structure of 3E9 antibody Fab bound to marinobufagenin
分子名称: (3beta,5beta,14alpha,15beta)-3,5-dihydroxy-14,15-epoxybufa-20,22-dienolide, 3E9 anti-marinobufagenin antibody Fab heavy chain, recloned with human IgG4 C region, ...
著者Franklin, M.C, Macdonald, L.E, McWhirter, J, Murphy, A.J.
登録日2019-07-29
公開日2019-12-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties.
Proc.Natl.Acad.Sci.USA, 117, 2020
6PYC
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Structure of kappa-on-heavy (KoH) antibody Fab bound to the cardiac hormone marinobufagenin
分子名称: (3beta,5beta,14alpha,15beta)-3,5-dihydroxy-14,15-epoxybufa-20,22-dienolide, KoH body Fab heavy chain, KoH body Fab light chain, ...
著者Franklin, M.C, Macdonald, L.E, McWhirter, J, Murphy, A.J.
登録日2019-07-29
公開日2019-12-25
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties.
Proc.Natl.Acad.Sci.USA, 117, 2020
7QI1
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BU of 7qi1 by Molmil
Crystal structure of human 14-3-3 protein beta in complex with CFTR peptide pS753pS768 and PPI stabilizer CY007424
分子名称: 14-3-3 protein theta, ARGININE, Cystic fibrosis transmembrane conductance regulator, ...
著者Stevers, L.M, Ottmann, C.
登録日2021-12-14
公開日2022-05-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR.
Nat Commun, 13, 2022

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件を2024-11-06に公開中

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