3MRA
| M3 TRANSMEMBRANE SEGMENT OF ALPHA-SUBUNIT OF NICOTINIC ACETYLCHOLINE RECEPTOR FROM TORPEDO CALIFORNICA, NMR, 15 STRUCTURES | 分子名称: | Acetylcholine receptor subunit alpha | 著者 | Lugovskoy, A.A, Maslennikov, I.V, Utkin, Y.N, Tsetlin, V.I, Cohen, J.B, Arseniev, A.S. | 登録日 | 1997-07-15 | 公開日 | 1998-01-21 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Spatial structure of the M3 transmembrane segment of the nicotinic acetylcholine receptor alpha subunit. Eur.J.Biochem., 255, 1998
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6I04
| Crystal structure of Sema domain of the Met receptor in complex with FAB | 分子名称: | Fab heavy chain, Fab light chain, Hepatocyte growth factor receptor | 著者 | Casaletto, J.B, Geddie, M.L, Abu-Yousif, A.O, Masson, K, Fulgham, A, Boudot, A, Maiwald, T, Kearns, J.D, Kohli, N, Su, S, Razlog, M, Raue, A, Kalra, A, Hakansson, M, Logan, D.T, Welin, M, Chattopadhyay, S, Harms, B.D, Nielsen, U.B, Schoeberl, B, Lugovskoy, A.A, MacBeath, G. | 登録日 | 2018-10-25 | 公開日 | 2019-03-13 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM. Proc.Natl.Acad.Sci.USA, 116, 2019
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6I07
| Crystal structure of EpCAM in complex with scFv | 分子名称: | Epithelial cell adhesion molecule, GLYCEROL, Single chain Fv | 著者 | Casaletto, J.B, Geddie, M.L, Abu-Yousif, A.O, Masson, K, Fulgham, A, Boudot, A, Maiwald, T, Kearns, J.D, Kohli, N, Su, S, Razlog, M, Raue, A, Kalra, A, Hakansson, M, Logan, D.T, Welin, M, Chattopadhyay, S, Harms, B.D, Nielsen, U.B, Schoeberl, B, Lugovskoy, A.A, MacBeath, G. | 登録日 | 2018-10-25 | 公開日 | 2019-03-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM. Proc.Natl.Acad.Sci.USA, 116, 2019
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6HYG
| Heteromeric tandem IgG4/IgG1 Fc | 分子名称: | IgHG1 and IgHG4 hybrid, ZINC ION | 著者 | Casaletto, J.B, Geddie, M.L, Abu-Yousif, A.O, Masson, K, Fulgham, A, Boudot, A, Maiwald, T, Kearns, J.D, Kohli, N, Su, S, Razlog, M, Raue, A, Kalra, A, Hakansson, M, Logan, D.T, Welin, M, Chattopadhyay, S, Harms, B.D, Nielsen, U.B, Schoeberl, B, Lugovskoy, A.A, MacBeath, G. | 登録日 | 2018-10-21 | 公開日 | 2019-03-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM. Proc.Natl.Acad.Sci.USA, 116, 2019
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1RF8
| Solution structure of the yeast translation initiation factor eIF4E in complex with m7GDP and eIF4GI residues 393 to 490 | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Eukaryotic initiation factor 4F subunit p150, Eukaryotic translation initiation factor 4E, ... | 著者 | Gross, J.D, Moerke, N.J, von der Haar, T, Lugovskoy, A.A, Sachs, A.B, McCarthy, J.E.G, Wagner, G. | 登録日 | 2003-11-07 | 公開日 | 2003-12-23 | 最終更新日 | 2024-03-06 | 実験手法 | SOLUTION NMR | 主引用文献 | Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E. Cell(Cambridge,Mass.), 115, 2003
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1IBX
| NMR STRUCTURE OF DFF40 AND DFF45 N-TERMINAL DOMAIN COMPLEX | 分子名称: | CHIMERA OF IGG BINDING PROTEIN G AND DNA FRAGMENTATION FACTOR 45, DNA FRAGMENTATION FACTOR 40 | 著者 | Zhou, P, Lugovskoy, A.A, McCarty, J.S, Li, P, Wagner, G. | 登録日 | 2001-03-29 | 公開日 | 2001-05-02 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of DFF40 and DFF45 N-terminal domain complex and mutual chaperone activity of DFF40 and DFF45. Proc.Natl.Acad.Sci.USA, 98, 2001
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1JQ4
| [2Fe-2S] Domain of Methane Monooxygenase Reductase from Methylococcus capsulatus (Bath) | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, METHANE MONOOXYGENASE COMPONENT C | 著者 | Mueller, J, Lugovskoy, A.A, Wagner, G, Lippard, S.J. | 登録日 | 2001-08-03 | 公開日 | 2002-01-09 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of the [2Fe-2S] ferredoxin domain from soluble methane monooxygenase reductase and interaction with its hydroxylase. Biochemistry, 41, 2002
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1D4B
| CIDE-N DOMAIN OF HUMAN CIDE-B | 分子名称: | HUMAN CELL DEATH-INDUCING EFFECTOR B | 著者 | Lugovskoy, A, Zhou, P, Chou, J, McCarty, J, Li, P, Wagner, G. | 登録日 | 1999-10-02 | 公開日 | 1999-12-17 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the CIDE-N domain of CIDE-B and a model for CIDE-N/CIDE-N interactions in the DNA fragmentation pathway of apoptosis. Cell(Cambridge,Mass.), 99, 1999
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2AZ5
| Crystal Structure of TNF-alpha with a small molecule inhibitor | 分子名称: | 6,7-DIMETHYL-3-[(METHYL{2-[METHYL({1-[3-(TRIFLUOROMETHYL)PHENYL]-1H-INDOL-3-YL}METHYL)AMINO]ETHYL}AMINO)METHYL]-4H-CHROMEN-4-ONE, Tumor necrosis factor (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) (Cachectin) [Contains: Tumor necrosis factor, membrane form; Tumor necrosis factor, ... | 著者 | He, M.M. | 登録日 | 2005-09-09 | 公開日 | 2005-11-29 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Small-molecule inhibition of TNF-alpha. Science, 310, 2005
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