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Crystal Structure and functional characterization of the thermophilic prolyl isomerase and chaperone SlyD
分子名称:	Peptidyl-prolyl cis-trans isomerase, Suc-Ala-Leu-Pro-Phe-pNA, ZINC ION
著者	Loew, C, Neumann, P, Weininger, U, Stubbs, M.T, Balbach, J.
登録日	2010-02-18
公開日	2010-03-31
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (2.55 Å)
主引用文献	Crystal Structure Determination and Functional Characterization of the Metallochaperone SlyD from Thermus thermophilus J.Mol.Biol., 398, 2010

3CGM

Crystal structure of thermophilic SlyD
分子名称:	GLYCEROL, NICKEL (II) ION, Peptidyl-prolyl cis-trans isomerase, ...
著者	Loew, C, Neumann, P, Stubbs, M.T, Balbach, J.
登録日	2008-03-06
公開日	2009-03-10
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (2.41 Å)
主引用文献	Crystal Structure Determination and Functional Characterization of the Metallochaperone SlyD from Thermus thermophilus J.Mol.Biol., 398, 2010

2RFM

Structure of a Thermophilic Ankyrin Repeat Protein
分子名称:	1,3-BUTANEDIOL, CHLORIDE ION, GLYCEROL, ...
著者	Loew, C, Weininger, U, Neumann, P, Stubbs, M.T, Balbach, J.
登録日	2007-10-01
公開日	2008-03-11
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (1.65 Å)
主引用文献	Structural insights into an equilibrium folding intermediate of an archaeal ankyrin repeat protein Proc.Natl.Acad.Sci.Usa, 105, 2008

3CGN

Crystal Structure of thermophilic SlyD
分子名称:	Peptidyl-prolyl cis-trans isomerase, SULFATE ION
著者	Neumann, P, Loew, C, Stubbs, M.T, Balbach, J.
登録日	2008-03-06
公開日	2009-03-10
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (2.7 Å)
主引用文献	Crystal Structure Determination and Functional Characterization of the Metallochaperone SlyD from Thermus thermophilus J.Mol.Biol., 398, 2010

2MX7

Solution structure of the internal EH domain of gamma-synergin
分子名称:	Synergin gamma
著者	Kovermann, M, Weininger, U, Loew, C.
登録日	2014-12-16
公開日	2015-12-30
最終更新日	2024-05-01
実験手法	SOLUTION NMR
主引用文献	Solution structure of the internal EH domain of gamma-synergin To be Published

6XZF

Nanobody in complex with eGFP
分子名称:	Nanobody targeted against eGFP, TERBIUM(III) ION, eGFP
著者	Pompidor, G, Zimmermann, S, Loew, C, Schneider, T.
登録日	2020-02-04
公開日	2021-02-17
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Engineered nanobodies with a lanthanide binding motif for crystallographic phasing To Be Published

6XYF

Nanobody 22
分子名称:	Nanobody 22, SODIUM ION
著者	Pompidor, G, Zimmermann, S, Loew, C, Schneider, T.
登録日	2020-01-30
公開日	2021-02-10
最終更新日	2024-01-24
実験手法	X-RAY DIFFRACTION (1.11097 Å)
主引用文献	Engineered nanobodies with a lanthanide binding motif for crystallographic phasing To Be Published

6XYM

Nbe-LBM
分子名称:	Nbe-LBM, TERBIUM(III) ION
著者	Pompidor, G, Zimmermann, S, Loew, C, Schneider, T.
登録日	2020-01-30
公開日	2021-02-10
実験手法	X-RAY DIFFRACTION (1.2 Å)
主引用文献	Engineered nanobodies with a lanthanide binding motif for crystallographic phasing To Be Published

6Y0E

Nbe LBM
分子名称:	NBe-LBM, TERBIUM(III) ION
著者	Pompidor, G, Zimmermann, S, Loew, C, Schneider, T.
登録日	2020-02-07
公開日	2021-02-17
実験手法	X-RAY DIFFRACTION (1.5 Å)
主引用文献	Engineered nanobodies with a lanthanide binding motif for crystallographic phasing To Be Published

6Y1R

Nb22-LBT
分子名称:	Nb22-LBT, SULFATE ION, TERBIUM(III) ION
著者	Pompidor, G, Zimmermann, S, Loew, C, Schneider, T.
登録日	2020-02-13
公開日	2021-02-24
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Engineered nanobodies with a lanthanide binding motif for crystallographic phasing To Be Published

6G73

The dynamic nature of the VDAC1 channels in bilayers: human VDAC1 at 3.3 Angstrom resolution
分子名称:	1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Voltage-dependent anion-selective channel protein 1
著者	Razeto, A, Gribbon, P, Loew, C.
登録日	2018-04-04
公開日	2019-04-24
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (3.27 Å)
主引用文献	The dynamic nature of the VDAC1 channels in bilayers as revealed by two crystal structures of the human isoform in bicelles at 2.7 and 3.3 Angstrom resolution: implications for VDAC1 voltage-dependent mechanism and for its oligomerization To Be Published

6G6U

The dynamic nature of the VDAC1 channels in bilayers: human VDAC1 at 2.7 Angstrom resolution
分子名称:	1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, NITRATE ION, Voltage-dependent anion-selective channel protein 1
著者	Razeto, A, Gribbon, P, Loew, C.
登録日	2018-04-03
公開日	2019-04-10
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (2.74 Å)
主引用文献	The dynamic nature of the VDAC1 channels in bilayers as revealed by two crystal structures of the human isoform in bicelles at 2.7 and 3.3 Angstrom resolution: implications for VDAC1 voltage-dependent mechanism and for its oligomerization To Be Published

4NY3

Human PTPA in complex with peptide
分子名称:	GLYCEROL, SULFATE ION, Serine/threonine-protein phosphatase 2A activator, ...
著者	Loew, C, Quistgaard, E.M, Nordlund, P.
登録日	2013-12-10
公開日	2014-07-23
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (1.797 Å)
主引用文献	Structural basis for PTPA interaction with the invariant C-terminal tail of PP2A. Biol.Chem., 395, 2014

2RND

Structure of the N-terminal BARpeptide in DPC micelles
分子名称:	Myc box-dependent-interacting protein 1
著者	Loew, C, Weininger, U, Balbach, J.
登録日	2007-12-16
公開日	2008-10-14
最終更新日	2024-05-29
実験手法	SOLUTION NMR
主引用文献	Structure and dynamics of helix-0 of the N-BAR domain in lipid micelles and bilayers Biophys.J., 95, 2008

2RMY

Structure of the N-terminal BARpeptide in SDS micelles
分子名称:	Myc box-dependent-interacting protein 1
著者	Loew, C, Weininger, U, Balbach, J.
登録日	2007-12-03
公開日	2008-10-14
最終更新日	2024-05-29
実験手法	SOLUTION NMR
主引用文献	Structure and dynamics of helix-0 of the N-BAR domain in lipid micelles and bilayers Biophys.J., 95, 2008

6EZI

PDZK1 domain 4 in complex with C-terminal peptide of human PepT2.
分子名称:	GLYCEROL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Solute carrier family 15 member 2
著者	Loew, C, Flayhan, A, Pieprzyk, J.
登録日	2017-11-15
公開日	2018-09-26
最終更新日	2024-01-17
実験手法	X-RAY DIFFRACTION (1.503321 Å)
主引用文献	Probing the Architecture of a Multi-PDZ Domain Protein: Structure of PDZK1 in Solution. Structure, 26, 2018

8R8Q

Lysosomal peptide transporter
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Glycosylated lysosomal membrane protein, Major facilitator superfamily domain-containing protein 1
著者	Jungnickel, K.E.J, Loew, C.
登録日	2023-11-29
公開日	2024-05-01
最終更新日	2024-07-24
実験手法	ELECTRON MICROSCOPY (4.08 Å)
主引用文献	MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes. Nat.Cell Biol., 26, 2024

7ZC2

Dipeptide and tripeptide Permease C (DtpC)
分子名称:	Amino acid/peptide transporter
著者	Killer, M, Finocchio, G, Pardon, E, Steyaert, J, Loew, C.
登録日	2022-03-25
公開日	2022-07-06
最終更新日	2024-07-24
実験手法	ELECTRON MICROSCOPY (2.72 Å)
主引用文献	Cryo-EM Structure of an Atypical Proton-Coupled Peptide Transporter: Di- and Tripeptide Permease C. Front Mol Biosci, 9, 2022

3FT7

Crystal structure of an extremely stable dimeric protein from sulfolobus islandicus
分子名称:	GLYCEROL, Uncharacterized protein ORF56
著者	Neumann, P, Loew, C, Weininger, U, Stubbs, M.T.
登録日	2009-01-12
公開日	2009-10-20
最終更新日	2023-11-01
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Structure-Based Stability Analysis of an Extremely Stable Dimeric DNA Binding Protein from Sulfolobus islandicus Biochemistry, 48, 2009

4DT4

Crystal structure of the PPIase-chaperone SlpA with the chaperone binding site occupied by the linker of the purification tag
分子名称:	FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase
著者	Quistgaard, E.M, Nordlund, P, Loew, C.
登録日	2012-02-20
公開日	2012-07-04
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (1.35 Å)
主引用文献	High-resolution insights into binding of unfolded polypeptides by the PPIase chaperone SlpA. Faseb J., 26, 2012

5MMT

Inward open PepTSt from Streptococcus thermophilus crystallized in space group P3121
分子名称:	Di-or tripeptide:H+ symporter
著者	Quistgaard, E.M, Molledo, M.M, Nordlund, P, Loew, C.
登録日	2016-12-12
公開日	2017-01-25
最終更新日	2024-05-08
実験手法	X-RAY DIFFRACTION (3.4 Å)
主引用文献	Structure determination of a major facilitator peptide transporter: Inward facing PepTSt from Streptococcus thermophilus crystallized in space group P3121. PLoS ONE, 12, 2017

7A25

Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23)
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者	Hallberg, B.M, Das, H.
登録日	2020-08-16
公開日	2020-11-25
実験手法	ELECTRON MICROSCOPY (3.06 Å)
主引用文献	Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2. Nat Commun, 11, 2020

8AFO

Structure of fibronectin 2 and 3 of L1CAM at 2.0 Angstrom
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neural cell adhesion molecule L1
著者	Guedez, G, Loew, C.
登録日	2022-07-18
公開日	2023-03-08
実験手法	X-RAY DIFFRACTION (1.99 Å)
主引用文献	X-ray structure and function of fibronectin domains two and three of the neural cell adhesion molecule L1. Faseb J., 37, 2023

8B1K

DtpB-Nb132-NV
分子名称:	ASN-VAL, DECANE, DODECANE, ...
著者	Killer, M, Finocchio, G, Lei, J, Jungnickel, K, Kotov, V, Steinke, J, Bartels, K, Strauss, J, Dupeux, F, Humm, A.S, Cornaciu, I, Marquez, J, Pardon, E, Steyeart, J, Loew, C.
登録日	2022-09-09
公開日	2023-08-09
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Plasticity of the binding pocket in peptide transporters underpins promiscuous substrate recognition. Cell Rep, 42, 2023

8B1B

DtpB-Nb132-AL
分子名称:	ALA-LEU, DECANE, DODECANE, ...
著者	Killer, M, Finocchio, G, Lei, J, Jungnickel, K, Kotov, V, Steinke, J, Bartels, K, Strauss, J, Dupeux, F, Humm, A.S, Cornaciu, I, Marquez, J, Pardon, E, Steyeart, J, Loew, C.
登録日	2022-09-09
公開日	2023-08-09
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Plasticity of the binding pocket in peptide transporters underpins promiscuous substrate recognition. Cell Rep, 42, 2023

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