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Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase from Mycobacterium tuberculosis
分子名称:	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DIMETHYL SULFOXIDE, nicotinate-nucleotide adenylyltransferase
著者	Rodionova, I, Zuccola, H, Sorci, L, Aleshin, A.E, Kazanov, M, Sergienko, E, Rubin, E, Locher, C, Osterman, A.
登録日	2014-10-30
公開日	2015-01-28
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.417 Å)
主引用文献	Mycobacterial nicotinate mononucleotide adenylyltransferase: structure, mechanism, and implications for drug discovery. J. Biol. Chem., 290, 2015

Dual Inhibition of the Essential Protein Kinases A and B in Mycobacterium tuberculosis
分子名称:	3-methyl-1-(2-methylpropyl)butyl 4-O-beta-L-gulopyranosyl-beta-D-glucopyranoside, 5-{5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}thiophene-2-sulfonamide, Serine/threonine-protein kinase PknA
著者	Zuccola, H.J.
登録日	2017-09-20
公開日	2018-02-14
実験手法	X-RAY DIFFRACTION (2.88 Å)
主引用文献	Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions. ACS Med Chem Lett, 8, 2017

Dual Inhibition of the Essential Protein Kinases A and B in Mycobacterium tuberculosis
分子名称:	5-{5-chloro-4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}thiophene-2-sulfonamide, Serine/threonine-protein kinase PknB
著者	Zuccola, H.J.
登録日	2017-09-20
公開日	2018-02-14
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (3.01 Å)
主引用文献	Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions. ACS Med Chem Lett, 8, 2017