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BU of 4aof by Molmil

Selective small molecule inhibitor discovered by chemoproteomic assay platform reveals regulation of Th17 cell differentiation by PI3Kgamma
分子名称:	N-[6-(5-methylsulfonylpyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]ethanamide, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM
著者	Bergamini, G, Bell, K, Shimamura, S, Werner, T, Cansfield, A, Muller, K, Perrin, J, Rau, C, Ellard, K, Hopf, C, Doce, C, Leggate, D, Mangano, R, Mathieson, T, OMahony, A, Plavec, I, Rharbaoui, F, Reinhard, F, Savitski, M.M, Ramsden, N, Hirsch, E, Drewes, G, Rausch, O, Bantscheff, M, Neubauer, G.
登録日	2012-03-26
公開日	2012-05-09
最終更新日	2023-12-20
実験手法	X-RAY DIFFRACTION (3.3 Å)
主引用文献	A Selective Inhibitor Reveals Pi3Kgamma Dependence of T(H)17 Cell Differentiation. Nat.Chem.Biol., 8, 2012

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BU of 7o2i by Molmil

METTL3-METTL14 heterodimer bound to the SAM competitive small molecule inhibitor STM2457
分子名称:	DIMETHYL SULFOXIDE, N6-adenosine-methyltransferase catalytic subunit, N6-adenosine-methyltransferase non-catalytic subunit, ...
著者	Pilka, E.S, Blackaby, W, Hardick, D, Harper, C, Hewstone, D, Ridgill, M, Rotty, B, Rausch, O.
登録日	2021-03-30
公開日	2021-04-14
最終更新日	2024-01-31
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia. Nature, 593, 2021

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BU of 8ef3 by Molmil

Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ119-D
分子名称:	rhMZ119-D antibody heavy chain, rhMZ119-D antibody light chain
著者	Sankhala, R.S, Joyce, M.G.
登録日	2022-09-07
公開日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.672 Å)
主引用文献	Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023

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BU of 8ee8 by Molmil

Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ100-C in complex with ZIKV E glycoprotein
分子名称:	Envelope protein E, rhMZ100-C antibody heavy chain, rhMZ100-C antibody light chain
著者	Sankhala, R.S, Joyce, M.G.
登録日	2022-09-06
公開日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.803 Å)
主引用文献	Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023

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BU of 8ee5 by Molmil

Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ119-D in complex with ZIKV E glycoprotein
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, rhMZ119-D antibody heavy chain, ...
著者	Sankhala, R.S, Joyce, M.G.
登録日	2022-09-06
公開日	2023-08-30
実験手法	X-RAY DIFFRACTION (3.583 Å)
主引用文献	Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023

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BU of 8eed by Molmil

Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ107-B in complex with ZIKV E glycoprotein
分子名称:	Envelope protein E, rhMZ107-B antibody heavy chain, rhMZ107-B antibody light chain
著者	Sankhala, R.S, Joyce, M.G.
登録日	2022-09-07
公開日	2023-08-30
実験手法	X-RAY DIFFRACTION (3.487 Å)
主引用文献	Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023

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BU of 8eee by Molmil

Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ104-d in complex with ZIKV E glycoprotein
分子名称:	Envelope protein E, SULFATE ION, rhMZ104-D antibody heavy chain, ...
著者	Sankhala, R.S, Joyce, M.G.
登録日	2022-09-07
公開日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.819 Å)
主引用文献	Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023

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BU of 8eez by Molmil

Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ100-C
分子名称:	rhMZ100-C antibody heavy chain, rhMZ100-C antibody light chain
著者	Sankhala, R.S, Joyce, M.G.
登録日	2022-09-07
公開日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.25 Å)
主引用文献	Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023

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BU of 8ef0 by Molmil

Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ104-D
分子名称:	PHOSPHATE ION, ZINC ION, rhMZ104-D antibody heavy chain, ...
著者	Sankhala, R.S, Joyce, M.G.
登録日	2022-09-07
公開日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.55 Å)
主引用文献	Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023

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BU of 8ef1 by Molmil

Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ103-A
分子名称:	rhMZ103-A antibody heavy chain, rhMZ103-A antibody light chain
著者	Sankhala, R.S, Joyce, M.G.
登録日	2022-09-07
公開日	2023-08-30
実験手法	X-RAY DIFFRACTION (1.87 Å)
主引用文献	Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023

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BU of 8ef2 by Molmil

Crystal structure of a NHP anti-ZIKV neutralizing antibody rhMZ107-B
分子名称:	PHOSPHATE ION, rhMZ107-B antibody heavy chain, rhMZ107-B antibody light chain
著者	Sankhala, R.S, Joyce, M.G.
登録日	2022-09-07
公開日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.102 Å)
主引用文献	Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes. Cell Rep, 42, 2023

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件を2024-07-24に公開中

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