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8U29
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BU of 8u29 by Molmil
Prefusion structure of the PRD-0038 spike glycoprotein ectodomain trimer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PRD-0038 Spike glycoprotein, ...
著者Lee, J, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2023-09-05
公開日2023-12-06
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus.
Cell Host Microbe, 31, 2023
2QQR
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BU of 2qqr by Molmil
JMJD2A hybrid tudor domains
分子名称: JmjC domain-containing histone demethylation protein 3A, SULFATE ION
著者Lee, J, Botuyan, M.V, Mer, G.
登録日2007-07-26
公開日2007-12-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor.
Nat.Struct.Mol.Biol., 15, 2008
9CL9
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BU of 9cl9 by Molmil
WT 12C IM fraction, B-b3 with RluB bound
分子名称: 23S rRNA, Large ribosomal subunit protein bL20, Large ribosomal subunit protein bL21, ...
著者Lee, J, Sheng, K, Williamson, J.R.
登録日2024-07-10
公開日2024-07-24
実験手法ELECTRON MICROSCOPY (5.04 Å)
主引用文献50S ribosome assembly intermediates at low temperature reveal bound RluB
To Be Published
8T46
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BU of 8t46 by Molmil
Transporter associated with antigen processing (TAP) in the apo state
分子名称: Antigen peptide transporter 1, Antigen peptide transporter 2
著者Lee, J, Oldham, M.L, Chen, J.
登録日2023-06-08
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Principles of peptide selection by the transporter associated with antigen processing.
Proc.Natl.Acad.Sci.USA, 121, 2024
8T4J
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BU of 8t4j by Molmil
Transporter associated with antigen processing (TAP) bound to the 14-mer peptide LPAVVGLSPGEQEY
分子名称: Antigen peptide transporter 1, Antigen peptide transporter 2, HLA-B35 specific peptide
著者Lee, J, Oldham, M.L, Chen, J.
登録日2023-06-09
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Transporter associated with antigen processing (TAP) bound to the 14-mer peptide LPAVVGLSPGEQEY
To Be Published
8T4G
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BU of 8t4g by Molmil
Transporter associated with antigen processing (TAP) bound to the 9-mer peptide QYDDAVYKL
分子名称: Antigen peptide transporter 1, Antigen peptide transporter 2, HLA-C4 specific peptide
著者Lee, J, Oldham, M.L, Chen, J.
登録日2023-06-09
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Transporter associated with antigen processing (TAP) bound to the 9-mer peptide QYDDAVYKL
To Be Published
8T4F
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BU of 8t4f by Molmil
Transporter associated with antigen processing (TAP) bound to the 9-mer peptide RRYQKSTEL
分子名称: Antigen peptide transporter 1, Antigen peptide transporter 2, Histone H3.3C peptide
著者Lee, J, Oldham, M.L, Chen, J.
登録日2023-06-09
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Transporter associated with antigen processing (TAP) bound to the 9-mer peptide RRYQKSTEL
To Be Published
8T4I
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BU of 8t4i by Molmil
Transporter associated with antigen processing (TAP) bound to the 7-mer peptide RRYSTEL
分子名称: Antigen peptide transporter 1, Antigen peptide transporter 2, Synthetic 7-mer peptide
著者Lee, J, Oldham, M.L, Chen, J.
登録日2023-06-09
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Transporter associated with antigen processing (TAP) bound to the 7-mer peptide RRYSTEL
To Be Published
8T4H
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BU of 8t4h by Molmil
Transporter associated with antigen processing (TAP) bound to the 8-mer peptide RRYQSTEL
分子名称: Antigen peptide transporter 1, Antigen peptide transporter 2, Synthetic 8-mer peptide
著者Lee, J, Chen, J.
登録日2023-06-09
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Transporter associated with antigen processing (TAP) bound to the 8-mer peptide RRYQSTEL
To Be Published
8T4E
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BU of 8t4e by Molmil
Transporter associated with antigen processing (TAP) bound to the 9-mer peptide ILKEPVHGV
分子名称: Antigen peptide transporter 1, Antigen peptide transporter 2, Transframe peptide
著者Lee, J, Oldham, M.L, Chen, J.
登録日2023-06-09
公開日2024-06-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Transporter associated with antigen processing (TAP) bound to the 9-mer peptide ILKEPVHGV
To Be Published
2R64
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BU of 2r64 by Molmil
Crystal structure of a 3-aminoindazole compound with CDK2
分子名称: Cell division protein kinase 2, N-[5-(1,1-DIOXIDOISOTHIAZOLIDIN-2-YL)-1H-INDAZOL-3-YL]-2-(4-PIPERIDIN-1-YLPHENYL)ACETAMIDE
著者Lee, J, Choi, H, Kim, K.H, Jeong, S, Park, J.W, Baek, C.S, Lee, S.H.
登録日2007-09-05
公開日2008-09-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Synthesis and biological evaluation of 3,5-diaminoindazoles as cyclin-dependent kinase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
4QXL
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BU of 4qxl by Molmil
Crystal Structure of FLHE
分子名称: Flagellar protein flhE
著者Lee, J, Monzingo, A.F, Keatinge-Clay, A.T, Harshey, R.M.
登録日2014-07-21
公開日2015-01-14
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (1.512 Å)
主引用文献Structure of Salmonella FlhE, Conserved Member of a Flagellar Type III Secretion Operon.
J.Mol.Biol., 427, 2015
8WP9
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BU of 8wp9 by Molmil
Small-heat shock protein from Methanocaldococcus jannaschii, Hsp16.5
分子名称: Small heat shock protein HSP16.5
著者Lee, J, Ryu, B, Kim, T, Kim, K.K.
登録日2023-10-09
公開日2023-12-27
実験手法ELECTRON MICROSCOPY (2.49 Å)
主引用文献Cryo-EM structure of a 16.5-kDa small heat-shock protein from Methanocaldococcus jannaschii.
Int.J.Biol.Macromol., 258, 2024
8VQ9
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BU of 8vq9 by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
著者Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2024-01-18
公開日2024-07-24
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
8VQB
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BU of 8vqb by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
著者Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2024-01-18
公開日2024-07-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
8VQA
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BU of 8vqa by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
著者Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2024-01-18
公開日2024-07-24
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
8DRX
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BU of 8drx by Molmil
Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp10-nsp11 (C10) cut site sequence (form 2)
分子名称: Fusion protein of 3C-like proteinase nsp5 and nsp10-nsp11 (C10) cut site, SODIUM ION
著者Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J.
登録日2022-07-21
公開日2022-09-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
8DRS
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BU of 8drs by Molmil
Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp6-nsp7 (C6) cut site sequence
分子名称: 3C-like proteinase nsp5
著者Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J.
登録日2022-07-21
公開日2022-09-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
8DRT
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BU of 8drt by Molmil
Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp6-nsp7 (C6) cut site sequence (form 2)
分子名称: 3C-like proteinase nsp5
著者Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J.
登録日2022-07-21
公開日2022-09-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
8DRR
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BU of 8drr by Molmil
Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp4-nsp5 (C4) cut site sequence
分子名称: 3C-like proteinase nsp5, SODIUM ION
著者Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J.
登録日2022-07-21
公開日2022-09-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
8DRW
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BU of 8drw by Molmil
Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp9-nsp10 (C9) cut site sequence
分子名称: DI(HYDROXYETHYL)ETHER, Fusion protein of 3C-like proteinase nsp5 and nsp9-nsp10 (C9) cut site, PENTAETHYLENE GLYCOL, ...
著者Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J.
登録日2022-07-21
公開日2022-09-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
8DRU
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BU of 8dru by Molmil
Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp7-nsp8 (C7) cut site sequence
分子名称: DI(HYDROXYETHYL)ETHER, Fusion protein of 3C-like proteinase nsp5 and nsp7-nsp8 (C7) cut site, PENTAETHYLENE GLYCOL, ...
著者Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J.
登録日2022-07-21
公開日2022-09-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
8DRV
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BU of 8drv by Molmil
Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp8-nsp9 (C8) cut site sequence
分子名称: Fusion protein of 3C-like proteinase nsp5 and nsp8-nsp9 (C8) cut site, PENTAETHYLENE GLYCOL
著者Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J.
登録日2022-07-21
公開日2022-09-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
8DRY
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BU of 8dry by Molmil
Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp12-nsp13 (C12) cut site sequence
分子名称: DI(HYDROXYETHYL)ETHER, Fusion protein of 3C-like proteinase nsp5 and nsp12-nsp13 (C12) cut site
著者Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J.
登録日2022-07-21
公開日2022-09-21
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022
8DS0
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BU of 8ds0 by Molmil
Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp14-nsp15 (C14) cut site sequence (form 2)
分子名称: 3C-like proteinase nsp5, DI(HYDROXYETHYL)ETHER
著者Lee, J, Kenward, C, Worrall, L.J, Vuckovic, M, Paetzel, M, Strynadka, N.C.J.
登録日2022-07-21
公開日2022-09-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation.
Nat Commun, 13, 2022

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件を2024-10-09に公開中

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