1E83
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![BU of 1e83 by Molmil](/molmil-images/mine/1e83) | Cytochrome c' from Alcaligenes xylosoxidans - oxidized structure | 分子名称: | CYTOCHROME C', HEME C | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | 登録日 | 2000-09-15 | 公開日 | 2000-11-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase Embo J., 19, 2000
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1E85
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![BU of 1e85 by Molmil](/molmil-images/mine/1e85) | Cytochrome c' from Alcaligenes xylosoxidans - reduced structure with NO bound to proximal side of heme | 分子名称: | CYTOCHROME C', HEME C, NITRIC OXIDE | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | 登録日 | 2000-09-15 | 公開日 | 2000-11-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase. Embo J., 19, 2000
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1THT
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![BU of 1tht by Molmil](/molmil-images/mine/1tht) | STRUCTURE OF A MYRISTOYL-ACP-SPECIFIC THIOESTERASE FROM VIBRIO HARVEYI | 分子名称: | THIOESTERASE | 著者 | Lawson, D.M, Derewenda, U, Serre, L, Ferri, S, Szitter, R, Wei, Y, Meighen, E.A, Derewenda, Z.S. | 登録日 | 1994-04-19 | 公開日 | 1995-06-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of a myristoyl-ACP-specific thioesterase from Vibrio harveyi. Biochemistry, 33, 1994
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1ATG
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![BU of 1atg by Molmil](/molmil-images/mine/1atg) | AZOTOBACTER VINELANDII PERIPLASMIC MOLYBDATE-BINDING PROTEIN | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, PERIPLASMIC MOLYBDATE-BINDING PROTEIN, ... | 著者 | Lawson, D.M, Pau, R.N, Williams, C.E.M, Mitchenall, L.A. | 登録日 | 1997-08-14 | 公開日 | 1998-10-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Ligand size is a major determinant of specificity in periplasmic oxyanion-binding proteins: the 1.2 A resolution crystal structure of Azotobacter vinelandii ModA. Structure, 6, 1998
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1E84
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![BU of 1e84 by Molmil](/molmil-images/mine/1e84) | Cytochrome c' from Alcaligenes xylosoxidans - reduced structure | 分子名称: | CYTOCHROME C', HEME C | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | 登録日 | 2000-09-15 | 公開日 | 2000-11-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase Embo J., 19, 2000
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1E86
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![BU of 1e86 by Molmil](/molmil-images/mine/1e86) | Cytochrome c' from Alcaligenes xylosoxidans - reduced structure with CO bound to distal side of heme | 分子名称: | CARBON MONOXIDE, CYTOCHROME C', HEME C | 著者 | Lawson, D.M, Stevenson, C.E.M, Andrew, C.R, Eady, R.R. | 登録日 | 2000-09-15 | 公開日 | 2000-11-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Unprecedented Proximal Binding of Nitric Oxide to Heme: Implications for Guanylate Cyclase Embo J., 19, 2000
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7NFU
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![BU of 7nfu by Molmil](/molmil-images/mine/7nfu) | Crystal structure of C-terminally truncated Geobacillus thermoleovorans nucleoid occlusion protein Noc | 分子名称: | GLYCEROL, Nucleoid occlusion protein, SULFATE ION | 著者 | Jalal, A.S.B, Tran, N.T, Wu, L.J, Ramakrishnan, K, Rejzek, M, Stevenson, C.E.M, Lawson, D.M, Errington, J, Le, T.B.K. | 登録日 | 2021-02-07 | 公開日 | 2021-02-17 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | CTP regulates membrane-binding activity of the nucleoid occlusion protein Noc. Mol.Cell, 81, 2021
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7NG0
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![BU of 7ng0 by Molmil](/molmil-images/mine/7ng0) | Crystal structure of N- and C-terminally truncated Geobacillus thermoleovorans nucleoid occlusion protein Noc | 分子名称: | Nucleoid occlusion protein, SULFATE ION | 著者 | Jalal, A.S.B, Tran, N.T, Wu, L.J, Ramakrishnan, K, Rejzek, M, Stevenson, C.E.M, Lawson, D.M, Errington, J, Le, T.B.K. | 登録日 | 2021-02-08 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | CTP regulates membrane-binding activity of the nucleoid occlusion protein Noc. Mol.Cell, 81, 2021
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1E5K
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![BU of 1e5k by Molmil](/molmil-images/mine/1e5k) | CRYSTAL STRUCTURE OF THE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOBA (PROTEIN FA) FROM ESCHERICHIA COLI AT NEAR ATOMIC RESOLUTION | 分子名称: | CITRIC ACID, LITHIUM ION, MOLYBDOPTERIN-GUANINE DINUCLEOTIDE BIOSYNTHESIS PROTEIN A | 著者 | Stevenson, C.E.M, Sargent, F, Buchanan, G, Palmer, T, Lawson, D.M. | 登録日 | 2000-07-27 | 公開日 | 2000-11-07 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Crystal Structure of the Molybdenum Cofactor Biosynthesis Protein Moba from Escherichia Coli at Near Atomic Resolution Structure, 8, 2000
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8PFC
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![BU of 8pfc by Molmil](/molmil-images/mine/8pfc) | Crystal structure of binary complex between Aster yellows witches'-broom phytoplasma effector SAP05 and the zinc finger domain of SPL5 from Arabidopsis thaliana | 分子名称: | Sequence-variable mosaic (SVM) signal sequence domain-containing protein, Squamosa promoter-binding-like protein 5, ZINC ION | 著者 | Huang, W, Liu, Q, Maqbool, A, Stevenson, C.E.M, Lawson, D.M, Kamoun, S, Hogenhout, S.A. | 登録日 | 2023-06-15 | 公開日 | 2023-07-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Bimodular architecture of bacterial effector SAP05 that drives ubiquitin-independent targeted protein degradation. Proc.Natl.Acad.Sci.USA, 120, 2023
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8PFD
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![BU of 8pfd by Molmil](/molmil-images/mine/8pfd) | Crystal structure of binary complex between Aster yellows witches'-broom phytoplasma effector SAP05 and the von Willebrand Factor Type A domain of the proteasomal ubiquitin receptor Rpn10 from Arabidopsis thaliana | 分子名称: | 26S proteasome non-ATPase regulatory subunit 4 homolog, Sequence-variable mosaic (SVM) signal sequence domain-containing protein | 著者 | Huang, W, Liu, Q, Maqbool, A, Stevenson, C.E.M, Lawson, D.M, Kamoun, S, Hogenhout, S.A. | 登録日 | 2023-06-15 | 公開日 | 2023-07-05 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Bimodular architecture of bacterial effector SAP05 that drives ubiquitin-independent targeted protein degradation. Proc.Natl.Acad.Sci.USA, 120, 2023
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7OL9
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![BU of 7ol9 by Molmil](/molmil-images/mine/7ol9) | |
6HQ6
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![BU of 6hq6 by Molmil](/molmil-images/mine/6hq6) | Bacterial beta-1,3-oligosaccharide phosphorylase from GH149 | 分子名称: | 1,2-ETHANEDIOL, BICINE, Bacterial beta-1,3-oligosaccharide phosphorylase, ... | 著者 | Kuhaudomlarp, S, Stevenson, C.E.M, Lawson, D.M, Field, R.A. | 登録日 | 2018-09-24 | 公開日 | 2019-06-12 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The structure of a GH149 beta-(1 → 3) glucan phosphorylase reveals a new surface oligosaccharide binding site and additional domains that are absent in the disaccharide-specific GH94 glucose-beta-(1 → 3)-glucose (laminaribiose) phosphorylase. Proteins, 87, 2019
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6HQ8
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![BU of 6hq8 by Molmil](/molmil-images/mine/6hq8) | Bacterial beta-1,3-oligosaccharide phosphorylase from GH149 with laminarihexaose bound at a surface site | 分子名称: | 1,2-ETHANEDIOL, BICINE, Beta-1,3-oligosaccharide phosphorylase, ... | 著者 | Kuhaudomlarp, S, Stevenson, C.E.M, Lawson, D.M, Field, R.A. | 登録日 | 2018-09-24 | 公開日 | 2019-06-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | The structure of a GH149 beta-(1 → 3) glucan phosphorylase reveals a new surface oligosaccharide binding site and additional domains that are absent in the disaccharide-specific GH94 glucose-beta-(1 → 3)-glucose (laminaribiose) phosphorylase. Proteins, 87, 2019
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8QA9
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![BU of 8qa9 by Molmil](/molmil-images/mine/8qa9) | Crystal structure of the RK2 plasmid encoded co-complex of the C-terminally truncated transcriptional repressor protein KorB complexed with the partner repressor protein KorA bound to OA-DNA | 分子名称: | DNA (5'-D(*TP*GP*TP*TP*TP*AP*GP*CP*TP*AP*AP*AP*CP*A)-3'), SULFATE ION, Transcriptional repressor protein KorB, ... | 著者 | McLean, T.C, Mundy, J.E.A, Lawson, D.M, Le, T.B.K. | 登録日 | 2023-08-22 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of the RK2 plasmid encoded co-complex of the C-terminally truncated transcriptional repressor protein KorB complexed with the partner repressor protein KorA bound to OA-DNA To Be Published
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8QA8
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5O98
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![BU of 5o98 by Molmil](/molmil-images/mine/5o98) | Binary complex of Catharanthus roseus Vitrosamine Synthase with NADP+ | 分子名称: | Alcohol dehydrogenase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Stavrinides, A.K, Tatsis, E.C, Dang, T.T, Caputi, L, Stevenson, C.E.M, Lawson, D.M, Schneider, B, O'Connor, S.E. | 登録日 | 2017-06-16 | 公開日 | 2018-02-21 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Discovery of a Short-Chain Dehydrogenase from Catharanthus roseus that Produces a New Monoterpene Indole Alkaloid. Chembiochem, 19, 2018
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5NZ8
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![BU of 5nz8 by Molmil](/molmil-images/mine/5nz8) | Clostridium thermocellum cellodextrin phosphorylase with cellotetraose and phosphate bound | 分子名称: | Cellodextrin phosphorylase, PHOSPHATE ION, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | O'Neill, E.C, Pergolizzi, G, Stevenson, C.E.M, Lawson, D.M, Nepogodiev, S.A, Field, R.A. | 登録日 | 2017-05-12 | 公開日 | 2017-08-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Cellodextrin phosphorylase from Ruminiclostridium thermocellum: X-ray crystal structure and substrate specificity analysis. Carbohydr. Res., 451, 2017
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5NZ7
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![BU of 5nz7 by Molmil](/molmil-images/mine/5nz7) | Clostridium thermocellum cellodextrin phosphorylase ligand free form | 分子名称: | CHLORIDE ION, Cellodextrin phosphorylase | 著者 | O'Neill, E.C, Pergolizzi, G, Stevenson, C.E.M, Lawson, D.M, Nepogodiev, S.A, Field, R.A. | 登録日 | 2017-05-12 | 公開日 | 2017-08-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Cellodextrin phosphorylase from Ruminiclostridium thermocellum: X-ray crystal structure and substrate specificity analysis. Carbohydr. Res., 451, 2017
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3ZMD
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![BU of 3zmd by Molmil](/molmil-images/mine/3zmd) | Crystal structure of AbsC, a MarR family transcriptional regulator from Streptomyces coelicolor | 分子名称: | 1,2-ETHANEDIOL, 2-HYDROXYBENZOIC ACID, CHLORIDE ION, ... | 著者 | Stevenson, C.E.M, Kock, H, Mootien, S, Davies, S.C, Bibb, M.J, Lawson, D.M. | 登録日 | 2013-02-07 | 公開日 | 2013-02-20 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal Structure of Absc, a Marr Family Transcriptional Regulator from Streptomyces Coelicolor To be Published
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7P2W
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![BU of 7p2w by Molmil](/molmil-images/mine/7p2w) | E.coli GyrB24 with inhibitor LMD92 (EBL2682) | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[[3,4-bis(chloranyl)-5-methyl-1H-pyrrol-2-yl]carbonylamino]-4-[(3-carboxyphenyl)methoxy]-1,3-benzothiazole-6-carboxylic acid, DNA gyrase subunit B, ... | 著者 | Stevenson, C.E.M, Lawson, D.M, Maxwell, A.M, Henderson, S.R, Kikelj, D, Durcik, M, Zega, A, Zidar, N, Ilas, J, Tomasic, T, Masic, L.P. | 登録日 | 2021-07-06 | 公開日 | 2022-07-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa. J.Med.Chem., 66, 2023
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7P2X
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![BU of 7p2x by Molmil](/molmil-images/mine/7p2x) | E.coli GyrB24 with inhibitor KOB20 (EBL2583) | 分子名称: | (2Z)-2-[[4,5-bis(bromanyl)-1H-pyrrol-2-yl]carbonylimino]-3-(phenylmethyl)-1,3-benzothiazole-6-carboxylic acid, DNA gyrase subunit B, PHOSPHATE ION | 著者 | Stevenson, C.E.M, Lawson, D.M, Maxwell, A.M, Henderson, S.R, Kikelj, D, Benek, O, Zega, A, Zidar, N, Ilas, J, Tomasic, T, Masic, L.P. | 登録日 | 2021-07-06 | 公開日 | 2022-07-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | E.coli GyrB24 with inhibitor KOB20 (EBL2583) TO BE PUBLISHED
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7P2M
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![BU of 7p2m by Molmil](/molmil-images/mine/7p2m) | E.coli GyrB24 with inhibitor LMD43 (EBL2560) | 分子名称: | 2-[[3,4-bis(chloranyl)-5-methyl-1~{H}-pyrrol-2-yl]carbonylamino]-4-phenylmethoxy-1,3-benzothiazole-6-carboxylic acid, DNA gyrase subunit B, PHOSPHATE ION | 著者 | Stevenson, C.E.M, Lawson, D.M, Maxwell, A.M, Henderson, S.R, Kikelj, D, Durcik, M, Zega, A, Zidar, N, Ilas, J, Tomasic, T, Masic, L.P. | 登録日 | 2021-07-06 | 公開日 | 2022-07-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | 主引用文献 | Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa. J.Med.Chem., 66, 2023
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7P2N
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![BU of 7p2n by Molmil](/molmil-images/mine/7p2n) | E.coli GyrB24 with inhibitor LSJ38 (EBL2684) | 分子名称: | 2-[[3,4-bis(chloranyl)-5-methyl-1H-pyrrol-2-yl]carbonylamino]-5-oxidanyl-1,3-benzothiazole-6-carboxylic acid, DNA gyrase subunit B, PHOSPHATE ION | 著者 | Stevenson, C.E.M, Lawson, D.M, Maxwell, A.M, Henderson, S.R, Kikelj, D, Zega, A, Zidar, N, Ilas, J, Tomasic, T, Masic, L.P. | 登録日 | 2021-07-06 | 公開日 | 2022-07-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.16 Å) | 主引用文献 | Exploring the 5-Substituted 2-Aminobenzothiazole-Based DNA Gyrase B Inhibitors Active against ESKAPE Pathogens. Acs Omega, 8, 2023
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5L40
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![BU of 5l40 by Molmil](/molmil-images/mine/5l40) | polyketide ketoreductase SimC7 - apo crystal form 1 | 分子名称: | polyketide ketoreductase SimC7 | 著者 | Schafer, M, Stevenson, C.E.M, Wilkinson, B, Lawson, D.M, Buttner, M.J. | 登録日 | 2016-05-24 | 公開日 | 2016-10-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Substrate-Assisted Catalysis in Polyketide Reduction Proceeds via a Phenolate Intermediate. Cell Chem Biol, 23, 2016
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