1A2D
 
 | | PYRIDOXAMINE MODIFIED MURINE ADIPOCYTE LIPID BINDING PROTEIN | | 分子名称: | ADIPOCYTE LIPID BINDING PROTEIN, CHLORIDE ION | | 著者 | Ory, J, Mazhary, A, Kuang, H, Davies, R, Distefano, M, Banaszak, L. | | 登録日 | 1997-12-29 | | 公開日 | 1998-07-01 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural characterization of two synthetic catalysts based on adipocyte lipid-binding protein.
Protein Eng., 11, 1998
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1A18
 | | PHENANTHROLINE MODIFIED MURINE ADIPOCYTE LIPID BINDING PROTEIN | | 分子名称: | ADIPOCYTE LIPID BINDING PROTEIN | | 著者 | Ory, J, Mazhary, A, Kuang, H, Davies, R, Distefano, M, Banaszak, L. | | 登録日 | 1997-12-23 | | 公開日 | 1998-07-01 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural characterization of two synthetic catalysts based on adipocyte lipid-binding protein.
Protein Eng., 11, 1998
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9B3K
 | | NorA in complex with Fab36 (NorA-BRIL fusion) | | 分子名称: | Fab36 heavy chain, Fab36 light chain, NorA-BRIL(3A) fusion | | 著者 | Xie, P, Li, Y, Kuang, H, Wang, D.N, Traaseth, N.J. | | 登録日 | 2024-03-19 | | 公開日 | 2024-12-11 | | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | | 主引用文献 | A shared helix approach to solve small membrane transporter structures using cryo-EM
To Be Published
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9B3L
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9B3M
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9B3O
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8UVB
 | | Structure of NaCT-PF4a complex | | 分子名称: | (2R)-2-hydroxy-2-[2-(2-methoxy-5-methylpyridin-3-yl)ethyl]butanedioic acid, SODIUM ION, Solute carrier family 13 member 5 | | 著者 | Li, Y, Wang, D.N, Mindell, J.A, Rice, W.J, Song, J, Mikusevic, V, Marden, J.J, Becerril, A, Kuang, H, Wang, B. | | 登録日 | 2023-11-02 | | 公開日 | 2024-12-25 | | 最終更新日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (2.13 Å) | | 主引用文献 | Substrate translocation and inhibition in human dicarboxylate transporter NaDC3.
Nat.Struct.Mol.Biol., 32, 2025
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8UVD
 | | Structure of NaDC3-PF4a complex | | 分子名称: | (2R)-2-hydroxy-2-[2-(2-methoxy-5-methylpyridin-3-yl)ethyl]butanedioic acid, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL, ... | | 著者 | Li, Y, Wang, D.N, Mindell, J.A, Rice, W.J, Song, J, Mikusevic, V, Marden, J.J, Becerril, A, Kuang, H, Wang, B. | | 登録日 | 2023-11-02 | | 公開日 | 2024-12-25 | | 最終更新日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (2.16 Å) | | 主引用文献 | Substrate translocation and inhibition in human dicarboxylate transporter NaDC3.
Nat.Struct.Mol.Biol., 32, 2025
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8UVC
 | | Structure of NaDC3-aKG complex | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-OXOGLUTARIC ACID, CHOLESTEROL, ... | | 著者 | Li, Y, Wang, D.N, Mindell, J.A, Rice, W.J, Song, J, Mikusevic, V, Marden, J.J, Becerril, A, Kuang, H, Wang, B. | | 登録日 | 2023-11-02 | | 公開日 | 2024-12-25 | | 最終更新日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (2.09 Å) | | 主引用文献 | Substrate translocation and inhibition in human dicarboxylate transporter NaDC3.
Nat.Struct.Mol.Biol., 32, 2025
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8UVE
 | | Structure of NaDC3-Succinate complex in Coo-Ci conformation | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL, Na(+)/dicarboxylate cotransporter 3, ... | | 著者 | Li, Y, Wang, D.N, Mindell, J.A, Rice, W.J, Song, J, Mikusevic, V, Marden, J.J, Becerril, A, Kuang, H, Wang, B. | | 登録日 | 2023-11-02 | | 公開日 | 2024-12-25 | | 最終更新日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Substrate translocation and inhibition in human dicarboxylate transporter NaDC3.
Nat.Struct.Mol.Biol., 32, 2025
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8UVH
 | | Structure of NaCT-succ complex | | 分子名称: | Solute carrier family 13 member 5 | | 著者 | Li, Y, Wang, D.N, Mindell, J.A, Rice, W.J, Song, J, Mikusevic, V, Marden, J.J, Becerril, A, Kuang, H, Wang, B. | | 登録日 | 2023-11-02 | | 公開日 | 2024-12-25 | | 最終更新日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (2.33 Å) | | 主引用文献 | Substrate translocation and inhibition in human dicarboxylate transporter NaDC3.
Nat.Struct.Mol.Biol., 32, 2025
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8UVF
 | | Structure of NaDC3-DMS complex in Ci-Ci conformation | | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL, Na(+)/dicarboxylate cotransporter 3, ... | | 著者 | Li, Y, Wang, D.N, Mindell, J.A, Rice, W.J, Song, J, Mikusevic, V, Marden, J.J, Becerril, A, Kuang, H, Wang, B. | | 登録日 | 2023-11-02 | | 公開日 | 2024-12-25 | | 最終更新日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (2.17 Å) | | 主引用文献 | Substrate translocation and inhibition in human dicarboxylate transporter NaDC3.
Nat.Struct.Mol.Biol., 32, 2025
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8UVG
 | | Structure of NaDC3-DMS complex in Co-Ci conformation | | 分子名称: | (2R,3S)-2,3-dimethylbutanedioic acid, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL, ... | | 著者 | Li, Y, Wang, D.N, Mindell, J.A, Rice, W.J, Song, J, Mikusevic, V, Marden, J.J, Becerril, A, Kuang, H, Wang, B. | | 登録日 | 2023-11-02 | | 公開日 | 2024-12-25 | | 最終更新日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | | 主引用文献 | Substrate translocation and inhibition in human dicarboxylate transporter NaDC3.
Nat.Struct.Mol.Biol., 32, 2025
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8UVI
 | | Structure of NaDC3-Succinate complex in Coo-Coo conformation | | 分子名称: | CHOLESTEROL, Na(+)/dicarboxylate cotransporter 3, SODIUM ION, ... | | 著者 | Li, Y, Wang, D.N, Mindell, J.A, Rice, W.J, Song, J, Mikusevic, V, Marden, J.J, Becerril, A, Kuang, H, Wang, B. | | 登録日 | 2023-11-03 | | 公開日 | 2024-12-25 | | 最終更新日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | | 主引用文献 | Substrate translocation and inhibition in human dicarboxylate transporter NaDC3.
Nat.Struct.Mol.Biol., 32, 2025
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8TTF
 | | NorA double mutant - E222QD307N at pH 7.5 | | 分子名称: | Heavy Chain of FabDA1 Variable Domain, Light Chain of FabDA1 Variable Domain, Quinolone resistance protein NorA | | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | | 登録日 | 2023-08-13 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | | 主引用文献 | Proton-coupled transport mechanism of the efflux pump NorA.
Nat Commun, 15, 2024
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8TTH
 | | NorA single mutant - D307N at pH 7.5 | | 分子名称: | Heavy Chain of FabDA1 Variable Domain, Light Chain of FabDA1 Variable Domain, Quinolone resistance protein NorA | | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | | 登録日 | 2023-08-13 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Proton-coupled transport mechanism of the efflux pump NorA.
Nat Commun, 15, 2024
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8TTE
 | | Protonated state of NorA at pH 5.0 | | 分子名称: | FabDA1 CDRH3 loop, Quinolone resistance protein NorA | | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | | 登録日 | 2023-08-13 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Proton-coupled transport mechanism of the efflux pump NorA.
Nat Commun, 15, 2024
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8TTG
 | | NorA single mutant - E222Q at pH 7.5 | | 分子名称: | FabDA1 CDRH3 loop, Quinolone resistance protein NorA | | 著者 | Li, J.P, Li, Y, Koide, A, Kuang, H.H, Torres, V.J, Koide, S, Wang, D.N, Traaseth, N.J. | | 登録日 | 2023-08-13 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | Proton-coupled transport mechanism of the efflux pump NorA.
Nat Commun, 15, 2024
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7LTO
 | | Nse5-6 complex | | 分子名称: | Non-structural maintenance of chromosome element 5, Ubiquitin-like protein SMT3,DNA repair protein KRE29 chimera | | 著者 | Yu, Y, Li, S.B, Zheng, S, Tangy, S, Koyi, C, Wan, B.B, Kung, H.H, Andrej, S, Alex, K, Patel, D.J, Zhao, X.L. | | 登録日 | 2021-02-19 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Integrative analysis reveals unique structural and functional features of the Smc5/6 complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7TVE
 | | ATP and DNA bound SMC5/6 core complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (68-MER), DNA (78-MER), ... | | 著者 | Yu, Y, Patel, D.J. | | 登録日 | 2022-02-04 | | 公開日 | 2022-06-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Cryo-EM structure of DNA-bound Smc5/6 reveals DNA clamping enabled by multi-subunit conformational changes.
Proc.Natl.Acad.Sci.USA, 119, 2022
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8T8E
 | | cryoEM structure of Smc5/6 5mer | | 分子名称: | DNA repair protein KRE29, Non-structural maintenance of chromosome element 5, Structural maintenance of chromosomes protein 6 | | 著者 | Yu, Y, Patel, D.J. | | 登録日 | 2023-06-22 | | 公開日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Molecular basis for Nse5-6 mediated regulation of Smc5/6 functions.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8T8F
 | | Smc5/6 8mer | | 分子名称: | DNA repair protein KRE29, Non-structural maintenance of chromosome element 4, Non-structural maintenance of chromosome element 5, ... | | 著者 | Yu, Y, Patel, D.J. | | 登録日 | 2023-06-22 | | 公開日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Molecular basis for Nse5-6 mediated regulation of Smc5/6 functions.
Proc.Natl.Acad.Sci.USA, 120, 2023
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9CES
 | | Guillardia theta Fanzor (GtFz) State 2 | | 分子名称: | DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*TP*AP*AP*AP*GP*GP*CP*CP*CP*CP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*GP*GP*GP*GP*CP*CP*TP*TP*TP*AP*AP*G)-3'), Maltose/maltodextrin-binding periplasmic protein,Guillardia theta Fanzor1, ... | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 187, 2024
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9CEW
 | | Spizellomyces punctatus Fanzor (SpuFz) State 3 | | 分子名称: | DNA (29-MER), DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), ... | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 187, 2024
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9CF0
 | | Parasitella parasitica Fanzor (PpFz) State 1 | | 分子名称: | DNA non-target strand, DNA target strand, Maltose/maltodextrin-binding periplasmic protein,Parasitella parasitica Fanzor 1, ... | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 187, 2024
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