7R22
| |
8XJG
| |
8XJE
| |
1B8P
| MALATE DEHYDROGENASE FROM AQUASPIRILLUM ARCTICUM | 分子名称: | PROTEIN (MALATE DEHYDROGENASE) | 著者 | Kim, S.Y, Hwang, K.Y, Kim, S.-H, Han, Y.S, Cho, Y. | 登録日 | 1999-02-02 | 公開日 | 1999-07-09 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for cold adaptation. Sequence, biochemical properties, and crystal structure of malate dehydrogenase from a psychrophile Aquaspirillium arcticum. J.Biol.Chem., 274, 1999
|
|
1B8U
| MALATE DEHYDROGENASE FROM AQUASPIRILLUM ARCTICUM | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXALOACETATE ION, PROTEIN (MALATE DEHYDROGENASE) | 著者 | Kim, S.Y, Hwang, K.Y, Kim, S.-H, Han, Y.S, Cho, Y. | 登録日 | 1999-02-02 | 公開日 | 1999-07-09 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for cold adaptation. Sequence, biochemical properties, and crystal structure of malate dehydrogenase from a psychrophile Aquaspirillium arcticum. J.Biol.Chem., 274, 1999
|
|
1B8V
| Malate dehydrogenase from Aquaspirillum arcticum | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (MALATE DEHYDROGENASE) | 著者 | Kim, S.Y, Hwang, K.Y, Kim, S.H, Han, Y.S, Cho, Y. | 登録日 | 1999-02-02 | 公開日 | 1999-07-09 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for cold adaptation. Sequence, biochemical properties, and crystal structure of malate dehydrogenase from a psychrophile Aquaspirillium arcticum. J.Biol.Chem., 274, 1999
|
|
3WE2
| |
3WE3
| |
4ZKF
| Crystal structure of human phosphodiesterase 12 | 分子名称: | 2',5'-phosphodiesterase 12, MAGNESIUM ION | 著者 | Kim, S.Y, Kohno, T, Mori, T, Kitano, K, Hakoshima, T. | 登録日 | 2015-04-30 | 公開日 | 2015-06-17 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Crystal structure of human phosphodiesterase To Be Published
|
|
8IEU
| |
8IEV
| |
5D43
| |
7OR2
| Crystal structure of UDP-N-acetylenolpyruvoylglucosamine reductase (MurB) from Pseudomonas aeruginosa in complex with FAD and a pyrazole derivative (fragment 4) | 分子名称: | 5-methyl-1-phenyl-pyrazole-4-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE, UDP-N-acetylenolpyruvoylglucosamine reductase | 著者 | Acebron-Garcia de Eulate, M, Blundell, T.L, Kim, S.Y, Mendes, V, Abell, C. | 登録日 | 2021-06-04 | 公開日 | 2021-11-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Discovery of Novel Inhibitors of Uridine Diphosphate- N -Acetylenolpyruvylglucosamine Reductase (MurB) from Pseudomonas aeruginosa , an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients. J.Med.Chem., 65, 2022
|
|
7OSQ
| Crystal structure of UDP-N-acetylenolpyruvoylglucosamine reductase (MurB) from Pseudomonas aeruginosa in complex with FAD and a pyrazole derivative (fragment 18) | 分子名称: | 5-methyl-1-phenyl-1,2,3-triazole-4-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE, UDP-N-acetylenolpyruvoylglucosamine reductase | 著者 | Acebron-Garcia de Eulate, M, Mayol-Llinas, J, Blundell, T.L, Kim, S.Y, Mendes, V, Abell, C. | 登録日 | 2021-06-09 | 公開日 | 2021-11-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Discovery of Novel Inhibitors of Uridine Diphosphate- N -Acetylenolpyruvylglucosamine Reductase (MurB) from Pseudomonas aeruginosa , an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients. J.Med.Chem., 65, 2022
|
|
5O08
| Crystal structure of Phosphopantetheine adenylyltransferase from Mycobacterium abcessus in complex with Dephospho-coenzyme A | 分子名称: | 1,2-ETHANEDIOL, DEPHOSPHO COENZYME A, Phosphopantetheine adenylyltransferase | 著者 | Thomas, S.E, Kim, S.Y, Mendes, V, Blaszczyk, M, Blundell, T.L. | 登録日 | 2017-05-16 | 公開日 | 2017-06-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.552 Å) | 主引用文献 | Structural Biology and the Design of New Therapeutics: From HIV and Cancer to Mycobacterial Infections: A Paper Dedicated to John Kendrew. J. Mol. Biol., 429, 2017
|
|
5O0D
| Crystal structure of Phosphopantetheine adenylyltransferase from Mycobacterium abcessus in complex with 3-Phenoxymandelic acid (Fragment 4) | 分子名称: | (2~{S})-2-oxidanyl-2-(3-phenoxyphenyl)ethanoic acid, Phosphopantetheine adenylyltransferase | 著者 | Thomas, S.E, Kim, S.Y, Mendes, V, Blaszczyk, M, Blundell, T.L. | 登録日 | 2017-05-16 | 公開日 | 2017-06-28 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.539 Å) | 主引用文献 | Structural Biology and the Design of New Therapeutics: From HIV and Cancer to Mycobacterial Infections: A Paper Dedicated to John Kendrew. J. Mol. Biol., 429, 2017
|
|
7ORZ
| Crystal structure of UDP-N-acetylenolpyruvoylglucosamine reductase (MurB) from Pseudomonas aeruginosa in complex with FAD and a pyrazole derivative (fragment 18) | 分子名称: | 1-phenyl-5-(trifluoromethyl)pyrazole-4-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Acebron-Garcia de Eulate, M, Blundell, T.L, Kim, S.Y, Mendes, V, Abell, C. | 登録日 | 2021-06-06 | 公開日 | 2021-11-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Discovery of Novel Inhibitors of Uridine Diphosphate- N -Acetylenolpyruvylglucosamine Reductase (MurB) from Pseudomonas aeruginosa , an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients. J.Med.Chem., 65, 2022
|
|
6KY2
| Crystal Structure of Arginine Kinase wild type from Daphnia magna | 分子名称: | Arginine kinase, PHOSPHATE ION | 著者 | Park, J.H, Rao, Z, Kim, S.Y, Kim, D.S. | 登録日 | 2019-09-16 | 公開日 | 2020-09-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Insight into Structural Aspects of Histidine 284 of Daphnia magna Arginine Kinase. Mol.Cells, 43, 2020
|
|
6KY3
| Structure of arginine kinase H284A mutant | 分子名称: | ARGININE, Arginine kinase, PHOSPHATE ION, ... | 著者 | Rao, Z, Park, J.H, Kim, S.Y, Kim, D.S. | 登録日 | 2019-09-16 | 公開日 | 2020-09-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Insight into Structural Aspects of Histidine 284 of Daphnia magna Arginine Kinase. Mol.Cells, 43, 2020
|
|
6L2U
| Soluble methane monooxygenase reductase FAD-binding domain from Methylosinus sporium. | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Methane monooxygenase | 著者 | Park, J.H, Ha, S.C, Rao, Z, Yoo, H, Yoon, C, Kim, S.Y, Kim, D.S, Lee, S.J. | 登録日 | 2019-10-07 | 公開日 | 2021-03-03 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Elucidation of the electron transfer environment in the MMOR FAD-binding domain from Methylosinus sporium 5. Dalton Trans, 50, 2021
|
|
7C04
| Crystal structure of human Trap1 with DN203492 | 分子名称: | 4-chloranyl-1-[[2-methoxy-4-(trifluoromethyl)phenyl]methyl]pyrazolo[3,4-d]pyrimidin-6-amine, Heat shock protein 75 kDa, mitochondrial | 著者 | Kim, D, Kim, D, Kim, S.Y, Lee, J.H, Kang, B.H, Kang, S, Lee, C. | 登録日 | 2020-04-30 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models. Bioorg.Chem., 101, 2020
|
|
7C05
| Crystal structure of human Trap1 with DN203495 | 分子名称: | 1-[(4-bromanyl-2-fluoranyl-phenyl)methyl]-4-chloranyl-pyrazolo[3,4-d]pyrimidin-6-amine, Heat shock protein 75 kDa, mitochondrial | 著者 | Kim, D, Kim, D, Kim, S.Y, Lee, J.H, Kang, B.H, Kang, S, Lee, C. | 登録日 | 2020-04-30 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Development of pyrazolo[3,4-d]pyrimidine-6-amine-based TRAP1 inhibitors that demonstrate in vivo anticancer activity in mouse xenograft models. Bioorg.Chem., 101, 2020
|
|
2B8I
| Crystal Structure and Functional Studies Reveal that PAS Factor from Vibrio vulnificus is a Novel Member of the Saposin-Fold Family | 分子名称: | PAS factor | 著者 | Lee, J.H, Yang, S.T, Rho, S.H, Im, Y.J, Kim, S.Y, Kim, Y.R, Kim, M.K, Kang, G.B, Kim, J.I, Rhee, J.H, Eom, S.H. | 登録日 | 2005-10-07 | 公開日 | 2006-02-14 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure and functional studies reveal that PAS factor from Vibrio vulnificus is a novel member of the saposin-fold family J.Mol.Biol., 355, 2006
|
|
7C7B
| Crystal structure of human TRAP1 with SJT009 | 分子名称: | 2-azanyl-9-[(6-bromanyl-1,3-benzodioxol-5-yl)methyl]-6-chloranyl-purin-8-ol, Heat shock protein 75 kDa, mitochondrial | 著者 | Kim, D, Yang, S, Yoon, N.G, Park, E, Kim, S.Y, Kang, B.H, Lee, C, Kang, S. | 登録日 | 2020-05-24 | 公開日 | 2021-05-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Design and Synthesis of TRAP1 Selective Inhibitors: H-Bonding with Asn171 Residue in TRAP1 Increases Paralog Selectivity. Acs Med.Chem.Lett., 12, 2021
|
|
7C7C
| Crystal structure of human TRAP1 with SJT104 | 分子名称: | 2-azanyl-9-[(4-bromanyl-2-fluoranyl-phenyl)methyl]-6-chloranyl-purin-8-ol, Heat shock protein 75 kDa, mitochondrial | 著者 | Kim, D, Yang, S, Yoon, N.G, Park, E, Kim, S.Y, Kang, B.H, Lee, C, Kang, S. | 登録日 | 2020-05-24 | 公開日 | 2021-05-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Design and Synthesis of TRAP1 Selective Inhibitors: H-Bonding with Asn171 Residue in TRAP1 Increases Paralog Selectivity. Acs Med.Chem.Lett., 12, 2021
|
|