8IG0
 
 | | Crystal structure of menin in complex with DS-1594b | | 分子名称: | (1R,2S,4R)-4-[[4-(5,6-dimethoxypyridazin-3-yl)phenyl]methylamino]-2-[methyl-[6-[2,2,2-tris(fluoranyl)ethyl]thieno[2,3-d]pyrimidin-4-yl]amino]cyclopentan-1-ol, DIMETHYL SULFOXIDE, Menin, ... | | 著者 | Suzuki, M, Yoneyama, T, Imai, E. | | 登録日 | 2023-02-20 | | 公開日 | 2023-03-22 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1.
Cancer Cell Int, 23, 2023
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6J6Y
 | | FGFR4 D2 - Fab complex | | 分子名称: | Fab Heavy chain, Fab light chain, Fibroblast growth factor receptor 4 | | 著者 | Takahashi, M, Hanzawa, H. | | 登録日 | 2019-01-16 | | 公開日 | 2019-08-07 | | 最終更新日 | 2019-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Preclinical Development of U3-1784, a Novel FGFR4 Antibody Against Cancer, and Avoidance of Its On-target Toxicity.
Mol.Cancer Ther., 18, 2019
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3Q3K
 | | Factor Xa in complex with a phenylenediamine derivative | | 分子名称: | Activated factor Xa heavy chain, CALCIUM ION, Factor X light chain, ... | | 著者 | Suzuki, M, Imai, E. | | 登録日 | 2010-12-22 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Design, synthesis and SAR of novel ethylenediamine and phenylenediamine derivatives as factor Xa inhibitors.
Bioorg.Med.Chem.Lett., 21, 2011
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