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6XE1
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BU of 6xe1 by Molmil
Structure of SARS-CoV-2 spike protein receptor binding domain in complex with a potent neutralizing antibody, CV30 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CV30 Fab Heavy chain, CV30 Fab Kappa chain, ...
著者Hurlburt, N.K, Pancera, M.
登録日2020-06-11
公開日2020-07-01
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation.
Nat Commun, 11, 2020
8VDL
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BU of 8vdl by Molmil
HB3VAR03 CIDRa1.4 domain with C7 Fab
分子名称: C7 Heavy Chain, C7 Light Chain, HB3VAR03 CIDRa1.4 domain, ...
著者Hurlburt, N.K, Pancera, M.
登録日2023-12-15
公開日2024-10-09
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Broadly inhibitory antibodies against severe malaria-associated PfEMP1 function through a structurally convergent mode of binding
To Be Published
6BN0
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BU of 6bn0 by Molmil
Avirulence protein 4 (Avr4) from Cladosporium fulvum bound to the hexasaccharide of chitin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Race-specific elicitor A4
著者Hurlburt, N.K, Fisher, A.J.
登録日2017-11-15
公開日2018-08-22
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of the Cladosporium fulvum Avr4 effector in complex with (GlcNAc)6 reveals the ligand-binding mechanism and uncouples its intrinsic function from recognition by the Cf-4 resistance protein.
PLoS Pathog., 14, 2018
7RAQ
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BU of 7raq by Molmil
Crystal structure of CV3-25 Fab bound to SARS-CoV-2 spike stem helix peptide
分子名称: CV3-25 Fab Heavy Chain, CV3-25 Fab Light Chain, GLYCEROL, ...
著者Hurlburt, N.K, Pancera, M.
登録日2021-07-02
公開日2022-04-13
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit.
Commun Biol, 5, 2022
5TOS
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BU of 5tos by Molmil
Botrytis-induced kinase 1 (BIK1) from Arabidopsis thaliana
分子名称: Serine/threonine-protein kinase BIK1
著者Hurlburt, N.K, Lal, N.K, Fisher, A.J.
登録日2016-10-18
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The Receptor-like Cytoplasmic Kinase BIK1 Localizes to the Nucleus and Regulates Defense Hormone Expression during Plant Innate Immunity.
Cell Host Microbe, 23, 2018
9BGE
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BU of 9bge by Molmil
Cryo-EM structure of mAb8-24 bound to 426c.WITO.TM.SOSIP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c.WITO.TM.SOSIP, ...
著者Hurlburt, N.K, Pancera, M.
登録日2024-04-18
公開日2024-09-04
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Short CDRL1 in intermediate VRC01-like mAbs is not sufficient to overcome key glycan barriers on HIV-1 Env.
J.Virol., 98, 2024
7M3I
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BU of 7m3i by Molmil
Structure of SARS-CoV-2 spike protein receptor binding domain in complex with a neutralizing antibody, CV2-75 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CV2-75 Fab Heavy chain, CV2-75 Fab Light chain, ...
著者Hurlburt, N.K, Pancera, M.
登録日2021-03-18
公開日2021-05-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects.
Cell Rep, 36, 2021
7RQQ
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BU of 7rqq by Molmil
Structure of chimeric antibody F10heavy_L9light with PfCSP peptide NANPNVDP
分子名称: 1,2-ETHANEDIOL, F10 Heavy Chain, L9 Kappa Chain, ...
著者Hurlburt, N.K, Pancera, M.
登録日2021-08-06
公開日2022-03-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria.
Cell Rep, 38, 2022
7RQR
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BU of 7rqr by Molmil
Structure of chimeric antibody L9heavy_F10light with PfCSP peptide NANPNVDP
分子名称: 1,2-ETHANEDIOL, F10 Kappa Chain, L9 Heavy Chain, ...
著者Hurlburt, N.K, Pancera, M.
登録日2021-08-06
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria.
Cell Rep, 38, 2022
7RQP
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BU of 7rqp by Molmil
Structure of PfCSP NPNV binding antibody L9
分子名称: L9 Heavy Chain, L9 Kappa Chain
著者Hurlburt, N.K, Pancera, M.
登録日2021-08-06
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria.
Cell Rep, 38, 2022
6VLB
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BU of 6vlb by Molmil
Crystal structure of ligand-free UDP-GlcNAc 2-epimerase from Neisseria meningitidis
分子名称: 1,2-ETHANEDIOL, SODIUM ION, UDP-N-acetylglucosamine 2-epimerase
著者Fisher, A.J, Hurlburt, N.K.
登録日2020-01-23
公開日2020-11-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural characterization of a nonhydrolyzing UDP-GlcNAc 2-epimerase from Neisseria meningitidis serogroup A.
Acta Crystallogr.,Sect.F, 76, 2020
6VLC
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BU of 6vlc by Molmil
Crystal structure of UDP-GlcNAc 2-epimerase from Neisseria meningitidis bound to UDP-GlcNAc
分子名称: UDP-N-acetylglucosamine 2-epimerase, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
著者Fisher, A.J, Hurlburt, N.K.
登録日2020-01-23
公開日2020-11-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural characterization of a nonhydrolyzing UDP-GlcNAc 2-epimerase from Neisseria meningitidis serogroup A.
Acta Crystallogr.,Sect.F, 76, 2020
4Z4A
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BU of 4z4a by Molmil
Avirulence protein 4 (Avr4) from Pseudocercospora fuligena
分子名称: 1,2-ETHANEDIOL, Carbohydrate-binding module family 14 protein
著者Hurlburt, N.K, Kohler, A.C, Fisher, A.J.
登録日2015-04-01
公開日2016-06-29
最終更新日2016-09-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Analysis of an Avr4 Effector Ortholog Offers Insight into Chitin Binding and Recognition by the Cf-4 Receptor.
Plant Cell, 28, 2016
7SG5
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BU of 7sg5 by Molmil
Structure of PfCSP peptide 21 with antibody CIS43_Var2
分子名称: CIS43_Var2 Fab Heavy chain, CIS43_Var2 Fab Light chain, GLYCEROL, ...
著者Tripathi, P, Kwong, P.D.
登録日2021-10-05
公開日2022-06-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Highly protective antimalarial antibodies via precision library generation and yeast display screening.
J.Exp.Med., 219, 2022
7SG6
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BU of 7sg6 by Molmil
Structure of PfCSP peptide 21 with antibody CIS43_Var10
分子名称: CIS43_Var10 Fab Heavy chain, CIS43_Var10 Fab Light chain, GLYCEROL, ...
著者Tripathi, P, Kwong, P.D.
登録日2021-10-05
公開日2022-06-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Highly protective antimalarial antibodies via precision library generation and yeast display screening.
J.Exp.Med., 219, 2022

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件を2024-11-06に公開中

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