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Crystal structure of human PHGDH in complex with Homoharringtonine
分子名称:	(3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, D-3-phosphoglycerate dehydrogenase
著者	Hsieh, C.H, Cheng, Y.S, Lee, Y.S, Huang, H.C, Juan, H.F.
登録日	2021-05-25
公開日	2022-12-07
最終更新日	2023-12-20
実験手法	X-RAY DIFFRACTION (2.99 Å)
主引用文献	Homoharringtonine as a PHGDH inhibitor: Unraveling metabolic dependencies and developing a potent therapeutic strategy for high-risk neuroblastoma. Biomed Pharmacother, 166, 2023

TYR115, GLN165 AND TRP209 CONTRIBUTE TO THE 1,2-EPOXY-3-(P-NITROPHENOXY)PROPANE CONJUGATING ACTIVITIES OF GLUTATHIONE S-TRANSFERASE CGSTM1-1
分子名称:	1-HYDROXY-2-S-GLUTATHIONYL-3-PARA-NITROPHENOXY-PROPANE, PROTEIN (GLUTATHIONE S-TRANSFERASE)
著者	Chern, M.K, Wu, T.C, Hsieh, C.H, Chou, C.C, Liu, L.F, Kuan, I.C, Yeh, Y.H, Hsiao, C.D, Tam, M.F.
登録日	2000-02-02
公開日	2000-08-30
最終更新日	2023-08-09
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Tyr115, gln165 and trp209 contribute to the 1, 2-epoxy-3-(p-nitrophenoxy)propane-conjugating activity of glutathione S-transferase cGSTM1-1. J.Mol.Biol., 300, 2000

Crystal structure of SARS coronavirus papain-like protease conjugated with beta-mercaptoethanol
分子名称:	BETA-MERCAPTOETHANOL, GLYCEROL, Replicase polyprotein 1a, ...
著者	Lin, M.H, Chou, C.Y.
登録日	2017-07-29
公開日	2018-01-10
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.65 Å)
主引用文献	Disulfiram can inhibit MERS and SARS coronavirus papain-like proteases via different modes Antiviral Res., 150, 2017

Crystal structure of SARS coronavirus papain-like protease in complex with glycerol
分子名称:	GLYCEROL, Replicase polyprotein 1a, SODIUM ION, ...
著者	Lin, M.H, Chou, C.Y.
登録日	2017-07-28
公開日	2018-01-10
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.65 Å)
主引用文献	Disulfiram can inhibit MERS and SARS coronavirus papain-like proteases via different modes Antiviral Res., 150, 2017