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2PRQ
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BU of 2prq by Molmil
X-ray crystallographic characterization of the Co(II)-substituted Tris-bound form of the aminopeptidase from Aeromonas proteolytica
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bacterial leucyl aminopeptidase, COBALT (II) ION
著者Munih, P, Moulin, A, Stamper, C.C, Bennet, B, Ringe, D, Petsko, G.A, Holz, R.C.
登録日2007-05-04
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献X-ray crystallographic characterization of the Co(II)-substituted Tris-bound form of the aminopeptidase from Aeromonas proteolytica.
J.Inorg.Biochem., 101, 2007
1WKM
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BU of 1wkm by Molmil
THE PRODUCT BOUND FORM OF THE MN(II)LOADED METHIONINE AMINOPEPTIDASE FROM HYPERTHERMOPHILE PYROCOCCUS FURIOSUS
分子名称: MANGANESE (II) ION, METHIONINE, Methionine aminopeptidase
著者Copik, A.J, Nocek, B.P, Jang, S.B, Swierczek, S.I, Ruebush, S, Meng, L, D'souza, V.M, Peters, J.W, Bennett, B, Holz, R.C.
登録日2004-06-01
公開日2005-02-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献EPR and X-ray crystallographic characterization of the product-bound form of the MnII-loaded methionyl aminopeptidase from Pyrococcus furiosus
Biochemistry, 44, 2005
2ANP
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BU of 2anp by Molmil
Functional Glutamate 151 to Histidine mutant of the aminopeptidase from Aeromonas Proteolytica.
分子名称: SODIUM ION, ZINC ION, leucyl aminopeptidase
著者Bzymek, K.P, Moulin, A, Swierczek, S.I, Ringe, D, Petsko, G.A, Holz, R.C.
登録日2005-08-11
公開日2005-10-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Kinetic, Spectroscopic, and X-ray Crystallographic Characterization of the Functional E151H Aminopeptidase from Aeromonas proteolytica.
Biochemistry, 44, 2005
4FM4
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BU of 4fm4 by Molmil
Wild Type Fe-type Nitrile Hydratase from Comamonas testosteroni Ni1
分子名称: FE (III) ION, Nitrile hydratase alpha subunit, Nitrile hydratase beta subunit, ...
著者Kuhn, M.L, Martinez, S, Gumataotao, N, Bornscheuer, U, Liu, D, Holz, R.C.
登録日2012-06-15
公開日2012-08-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.384 Å)
主引用文献The Fe-type nitrile hydratase from Comamonas testosteroni Ni1 does not require an activator accessory protein for expression in Escherichia coli.
Biochem.Biophys.Res.Commun., 424, 2012
1LOK
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BU of 1lok by Molmil
The 1.20 Angstrom Resolution Crystal Structure of the Aminopeptidase from Aeromonas proteolytica Complexed with Tris: A Tale of Buffer Inhibition
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bacterial leucyl aminopeptidase, SODIUM ION, ...
著者Desmarais, W.T, Bienvenue, D.L, Bzymek, K.P, Holz, R.C, Petsko, G.A, Ringe, D.
登録日2002-05-06
公開日2002-11-27
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献The 1.20 Angstrom Resolution Crystal Structure of the Aminopeptidase from Aeromonas proteolytica Complexed with Tris A tale of Buffer Inhibition
Structure, 10, 2002
3IC1
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BU of 3ic1 by Molmil
Crystal structure of zinc-bound succinyl-diaminopimelate desuccinylase from Haemophilus influenzae
分子名称: GLYCEROL, SULFATE ION, Succinyl-diaminopimelate desuccinylase, ...
著者Nocek, B.P, Gillner, D.M, Holz, R.C, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2009-07-17
公開日2009-09-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for catalysis by the mono- and dimetalated forms of the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase.
J.Mol.Biol., 397, 2010
3ISZ
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BU of 3isz by Molmil
Crystal structure of mono-zinc form of succinyl-diaminopimelate desuccinylase from Haemophilus influenzae
分子名称: SULFATE ION, Succinyl-diaminopimelate desuccinylase, ZINC ION
著者Nocek, B.P, Gillner, D.M, Holz, R.C, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2009-08-27
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for catalysis by the mono- and dimetalated forms of the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase.
J.Mol.Biol., 397, 2010
1TXR
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BU of 1txr by Molmil
X-ray crystal structure of bestatin bound to AAP
分子名称: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, Bacterial leucyl aminopeptidase, ZINC ION
著者Stamper, C.C, Holz, R.C, Ringe, D, Petsko, G.A.
登録日2004-07-06
公開日2004-07-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Spectroscopic and X-ray Crystallographic Characterization of Bestatin Bound to the Aminopeptidase from Aeromonas (Vibrio) proteolytica.
Biochemistry, 43, 2004
1RTQ
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BU of 1rtq by Molmil
The 0.95 Angstrom Resolution Crystal Structure of the Aminopeptidase from Aeromonas proteolytica
分子名称: Bacterial leucyl aminopeptidase, SODIUM ION, THIOCYANATE ION, ...
著者Desmarais, W, Bienvenue, D.L, Krzysztof, B.P, Holz, R.C, Petsko, G.A, Ringe, D.
登録日2003-12-10
公開日2004-02-10
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献The high-resolution structures of the neutral and the low pH crystals of aminopeptidase from Aeromonas proteolytica.
J.Biol.Inorg.Chem., 11, 2006
1CP6
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BU of 1cp6 by Molmil
1-BUTANEBORONIC ACID BINDING TO AEROMONAS PROTEOLYTICA AMINOPEPTIDASE
分子名称: 1-BUTANE BORONIC ACID, PROTEIN (AMINOPEPTIDASE), ZINC ION
著者Depaola, C.C, Bennett, B, Holz, R.C, Ringe, D, Petsko, G.A.
登録日1999-06-08
公開日1999-06-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献1-Butaneboronic acid binding to Aeromonas proteolytica aminopeptidase: a case of arrested development.
Biochemistry, 38, 1999
7SJZ
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BU of 7sjz by Molmil
Crystal structure of aS162A mutant of Co-type nitrile hydratase from Pseudonocardia thermophila
分子名称: Cobalt-containing nitrile hydratase subunit alpha, Cobalt-containing nitrile hydratase subunit beta
著者Ogutu, R.A.M.I, Holz, C.R, Bennett, B, St Maurice, M.
登録日2021-10-19
公開日2021-12-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Examination of the Catalytic Role of the Axial Cystine Ligand in the Co-Type Nitrile Hydratase from Pseudonocardia thermophila JCM 3095
Catalysts, 11, 2021
9D6J
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BU of 9d6j by Molmil
Nitrile hydratase BR52K mutant
分子名称: Cobalt-containing nitrile hydratase subunit alpha, Cobalt-containing nitrile hydratase subunit beta
著者Miller, C.G, Holz, R.C, Liu, D, Kaley, N.
登録日2024-08-15
公開日2024-08-28
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Role of second-sphere arginine residues in metal binding and metallocentre assembly in nitrile hydratases.
J Inorg Biochem, 256, 2024
9D6M
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BU of 9d6m by Molmil
Nitrile hydratase BR157K mutant
分子名称: Cobalt-containing nitrile hydratase subunit alpha, Cobalt-containing nitrile hydratase subunit beta
著者Miller, C.G, Holz, R.C, Liu, D, Kaley, N.
登録日2024-08-15
公開日2024-08-28
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Role of second-sphere arginine residues in metal binding and metallocentre assembly in nitrile hydratases.
J Inorg Biochem, 256, 2024
9D65
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BU of 9d65 by Molmil
Nitrile hydratase BR52A mutant
分子名称: Cobalt-containing nitrile hydratase subunit alpha, Cobalt-containing nitrile hydratase subunit beta
著者Miller, C.G, Holz, R.C, Liu, D, Kaley, N.
登録日2024-08-14
公開日2024-08-28
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Role of second-sphere arginine residues in metal binding and metallocentre assembly in nitrile hydratases.
J Inorg Biochem, 256, 2024
9D6K
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BU of 9d6k by Molmil
Nitrile hydratase BR157A mutant
分子名称: Cobalt-containing nitrile hydratase subunit alpha, Cobalt-containing nitrile hydratase subunit beta, OXYGEN ATOM
著者Miller, C.G, Holz, R.C, Liu, D, Kaley, N.
登録日2024-08-15
公開日2024-09-25
実験手法X-RAY DIFFRACTION (1.29 Å)
主引用文献Role of second-sphere arginine residues in metal binding and metallocentre assembly in nitrile hydratases.
J Inorg Biochem, 256, 2024
4ZGJ
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BU of 4zgj by Molmil
Double Mutant H80A/H81A of Fe-Type Nitrile Hydratase from Comamonas testosteroni Ni1
分子名称: FE (III) ION, Nitrile hydratase alpha subunit, Nitrile hydratase beta subunit
著者Wu, R, Martinez, S, Holz, R, Liu, D.
登録日2015-04-23
公開日2015-07-01
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Analyzing the catalytic role of active site residues in the Fe-type nitrile hydratase from Comamonas testosteroni Ni1.
J.Biol.Inorg.Chem., 20, 2015
4ZGD
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BU of 4zgd by Molmil
Mutant R157A of Fe-Type Nitrile Hydratase from Comamonas testosteroni Ni1
分子名称: FE (III) ION, Nitrile hydratase alpha subunit, Nitrile hydratase beta subunit
著者Wu, R, Martinez, S, Holz, R, Liu, D.
登録日2015-04-22
公開日2015-07-01
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Analyzing the catalytic role of active site residues in the Fe-type nitrile hydratase from Comamonas testosteroni Ni1.
J.Biol.Inorg.Chem., 20, 2015
4ZGE
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BU of 4zge by Molmil
Double Mutant H80W/H81W of Fe-Type Nitrile Hydratase from Comamonas testosteroni Ni1
分子名称: FE (III) ION, Nitrile hydratase alpha subunit, Nitrile hydratase beta subunit
著者Wu, R, Martinez, S, Holz, R, Liu, D.
登録日2015-04-22
公開日2015-07-01
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Analyzing the catalytic role of active site residues in the Fe-type nitrile hydratase from Comamonas testosteroni Ni1.
J.Biol.Inorg.Chem., 20, 2015
4H2K
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BU of 4h2k by Molmil
Crystal structure of the catalytic domain of succinyl-diaminopimelate desuccinylase from Haemophilus influenzae
分子名称: Succinyl-diaminopimelate desuccinylase, ZINC ION
著者Nocek, B, Jedrzejczak, R, Makowska-Grzyska, M, Starus, A, Holz, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2012-09-12
公開日2012-11-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献The dimerization domain in DapE enzymes is required for catalysis.
Plos One, 9, 2014
4O23
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BU of 4o23 by Molmil
Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from Neisseria meningitidis MC58
分子名称: SULFATE ION, Succinyl-diaminopimelate desuccinylase, ZINC ION
著者Nocek, B, Holz, R, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2013-12-16
公開日2014-01-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril.
Biochemistry, 54, 2015
4PQA
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BU of 4pqa by Molmil
Crystal Structure of succinyl-diaminopimelate desuccinylase from Neisseria meningitidis MC58 in complex with the Inhibitor Captopril
分子名称: L-CAPTOPRIL, SULFATE ION, Succinyl-diaminopimelate desuccinylase, ...
著者Nocek, B, Starus, A, Holz, R, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-03-01
公開日2014-04-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril.
Biochemistry, 54, 2015
4PPZ
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Crystal structure of zinc-bound succinyl-diaminopimelate desuccinylase from Neisseria meningitidis MC58
分子名称: PHOSPHATE ION, Succinyl-diaminopimelate desuccinylase, ZINC ION
著者Nocek, B, Holz, R, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-02-27
公開日2014-03-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril.
Biochemistry, 54, 2015
6UXU
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BU of 6uxu by Molmil
X-ray Crystal Structure of Chlorothalonil Dehalogenase: Analyzing the Catalytic Mechanism of Hydrolytic Dehalogenation
分子名称: Chlorothalonil hydrolytic dehalogenase, ZINC ION
著者Catlin, D.S, Liu, D.
登録日2019-11-08
公開日2020-05-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.962 Å)
主引用文献Structural basis for the hydrolytic dehalogenation of the fungicide chlorothalonil.
J.Biol.Chem., 295, 2020
5VO3
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BU of 5vo3 by Molmil
Crystal structure of DapE in complex with the products (succinic acid and diaminopimelic acid)
分子名称: 2,6-DIAMINOPIMELIC ACID, SUCCINIC ACID, Succinyl-diaminopimelate desuccinylase, ...
著者Nocek, B.
登録日2017-05-01
公開日2018-07-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.954 Å)
主引用文献Structural Evidence of a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism.
Biochemistry, 57, 2018
2DEA
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BU of 2dea by Molmil
Crystal Structure of the Aminopeptidase of Aeromonas proteolytica at pH 4.7
分子名称: Bacterial leucyl aminopeptidase, SODIUM ION, ZINC ION
著者Petsko, G.A, Ringe, D, Desmarais, W.
登録日2006-02-10
公開日2006-07-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献The high-resolution structures of the neutral and the low pH crystals of aminopeptidase from Aeromonas proteolytica.
J.Biol.Inorg.Chem., 11, 2006

 

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