1U8R
 
 | | Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions | | 分子名称: | COBALT (II) ION, Iron-dependent repressor ideR, SODIUM ION, ... | | 著者 | Wisedchaisri, G, Holmes, R.K, Hol, W.G.J. | | 登録日 | 2004-08-06 | | 公開日 | 2004-10-05 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal Structure of an IdeR-DNA Complex Reveals a Conformational Change in Activated IdeR for Base-specific Interactions.
J.Mol.Biol., 342, 2004
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1S5F
 | | Cholera holotoxin, Crystal form 2 | | 分子名称: | Cholera enterotoxin, A chain, SODIUM ION, ... | | 著者 | O'Neal, C.J, Amaya, E.I, Jobling, M.G, Holmes, R.K, Hol, W.G. | | 登録日 | 2004-01-20 | | 公開日 | 2004-04-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structures of an intrinsically active cholera toxin mutant yield insight into the toxin activation mechanism
Biochemistry, 43, 2004
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1S5E
 | | Cholera holotoxin, Crystal form 1 | | 分子名称: | Cholera enterotoxin, A chain precursor, SODIUM ION, ... | | 著者 | O'Neal, C.J, Amaya, E.I, Jobling, M.G, Holmes, R.K, Hol, W.G. | | 登録日 | 2004-01-20 | | 公開日 | 2004-04-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of an intrinsically active cholera toxin mutant yield
insight into the toxin activation mechanism
Biochemistry, 43, 2004
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1S5C
 | | Cholera holotoxin with an A-subunit Y30S mutation, Crystal form 1 | | 分子名称: | Cholera enterotoxin, A chain, SODIUM ION, ... | | 著者 | O'Neal, C.J, Amaya, E.I, Jobling, M.G, Holmes, R.K, Hol, W.G. | | 登録日 | 2004-01-20 | | 公開日 | 2004-04-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of an intrinsically active cholera toxin mutant yield
insight into the toxin activation mechanism
Biochemistry, 43, 2004
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1S5D
 | | Cholera holotoxin with an A-subunit Y30S mutation, Crystal form 2 | | 分子名称: | Cholera enterotoxin, A chain, GLYCEROL, ... | | 著者 | O'Neal, C.J, Amaya, E.I, Jobling, M.G, Holmes, R.K, Hol, W.G. | | 登録日 | 2004-01-20 | | 公開日 | 2004-04-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structures of an intrinsically active cholera toxin
mutant yield insight into the toxin activation mechanism
Biochemistry, 43, 2004
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1S5B
 | | Cholera holotoxin with an A-subunit Y30S mutation Form 3 | | 分子名称: | Cholera enterotoxin, A chain precursor, SODIUM ION, ... | | 著者 | O'Neal, C.J, Amaya, E.I, Jobling, M.G, Holmes, R.K, Hol, W.G. | | 登録日 | 2004-01-20 | | 公開日 | 2004-04-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Crystal structures of an intrinsically active cholera toxin mutant yield
insight into the toxin activation mechanism
Biochemistry, 43, 2004
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2ISZ
 | | Crystal structure of a two-domain IdeR-DNA complex crystal form I | | 分子名称: | Iron-dependent repressor ideR, NICKEL (II) ION, SODIUM ION, ... | | 著者 | Wisedchaisri, G, Chou, C.J, Wu, M, Roach, C, Rice, A.E, Holmes, R.K, Beeson, C, Hol, W.G. | | 登録日 | 2006-10-18 | | 公開日 | 2007-02-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.403 Å) | | 主引用文献 | Crystal structures, metal activation, and DNA-binding properties of two-domain IdeR from Mycobacterium tuberculosis
Biochemistry, 46, 2007
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2ISY
 | | Crystal structure of the nickel-activated two-domain iron-dependent regulator (IdeR) | | 分子名称: | Iron-dependent repressor ideR, NICKEL (II) ION, PHOSPHATE ION | | 著者 | Wisedchaisri, G, Chou, C.J, Wu, M, Roach, C, Rice, A.E, Holmes, R.K, Beeson, C, Hol, W.G. | | 登録日 | 2006-10-18 | | 公開日 | 2007-02-13 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.955 Å) | | 主引用文献 | Crystal structures, metal activation, and DNA-binding properties of two-domain IdeR from Mycobacterium tuberculosis
Biochemistry, 46, 2007
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2IT0
 | | Crystal structure of a two-domain IdeR-DNA complex crystal form II | | 分子名称: | ACETATE ION, Iron-dependent repressor ideR, NICKEL (II) ION, ... | | 著者 | Wisedchaisri, G, Chou, C.J, Wu, M, Roach, C, Rice, A.E, Holmes, R.K, Beeson, C, Hol, W.G. | | 登録日 | 2006-10-18 | | 公開日 | 2007-02-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structures, metal activation, and DNA-binding properties of two-domain IdeR from Mycobacterium tuberculosis
Biochemistry, 46, 2007
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2A5F
 | | Cholera toxin A1 subunit bound to its substrate, NAD+, and its human protein activator, ARF6 | | 分子名称: | ADP-ribosylation factor 6, Cholera enterotoxin, A chain, ... | | 著者 | O'Neal, C.J, Jobling, M.G, Holmes, R.K, Hol, W.G.J. | | 登録日 | 2005-06-30 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Structural basis for the activation of cholera toxin by human ARF6-GTP.
Science, 309, 2005
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2A5D
 | | Structural basis for the activation of cholera toxin by human ARF6-GTP | | 分子名称: | ADP-ribosylation factor 6, Cholera enterotoxin, A chain, ... | | 著者 | O'Neal, C.J, Jobling, M.G, Holmes, R.K, Hol, W.G.J. | | 登録日 | 2005-06-30 | | 公開日 | 2005-08-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for the activation of cholera toxin by human ARF6-GTP.
Science, 309, 2005
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2A5G
 | | Cholera toxin A1 subunit bound to ARF6(Q67L) | | 分子名称: | ADP-ribosylation factor 6, Cholera enterotoxin, A chain, ... | | 著者 | O'Neal, C.J, Jobling, M.G, Holmes, R.K, Hol, W.G.J. | | 登録日 | 2005-06-30 | | 公開日 | 2005-08-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Structural basis for the activation of cholera toxin by human ARF6-GTP.
Science, 309, 2005
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1C0W
 | | CRYSTAL STRUCTURE OF THE COBALT-ACTIVATED DIPHTHERIA TOXIN REPRESSOR-DNA COMPLEX REVEALS A METAL BINDING SH-LIKE DOMAIN | | 分子名称: | COBALT (II) ION, DIPHTHERIA TOXIN REPRESSOR, DNA (5'-D(P*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*CP*CP*TP*AP*CP*CP*CP*TP*AP*AP*T)-3'), ... | | 著者 | Pohl, E, Holmes, R.K, Hol, W.G. | | 登録日 | 1999-07-22 | | 公開日 | 2000-07-22 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structure of a cobalt-activated diphtheria toxin repressor-DNA complex reveals a metal-binding SH3-like domain.
J.Mol.Biol., 292, 1999
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1B1B
 | | IRON DEPENDENT REGULATOR | | 分子名称: | PROTEIN (IRON DEPENDENT REGULATOR), SULFATE ION, ZINC ION | | 著者 | Pohl, E, Holmes, R.K, Hol, W.G. | | 登録日 | 1998-11-19 | | 公開日 | 1999-12-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of the iron-dependent regulator (IdeR) from Mycobacterium tuberculosis shows both metal binding sites fully occupied.
J.Mol.Biol., 285, 1999
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1G3W
 | | CD-CYS102SER DTXR | | 分子名称: | CADMIUM ION, DIPHTHERIA TOXIN REPRESSOR, SULFATE ION | | 著者 | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | | 登録日 | 2000-10-25 | | 公開日 | 2001-10-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
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1G3T
 | | CYS102SER DTXR | | 分子名称: | DIPHTHERIA TOXIN REPRESSOR | | 著者 | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | | 登録日 | 2000-10-25 | | 公開日 | 2001-10-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
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1FWZ
 | | GLU20ALA DTXR | | 分子名称: | DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION | | 著者 | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | | 登録日 | 2000-09-25 | | 公開日 | 2001-09-25 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
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1G3S
 | | CYS102SER DTXR | | 分子名称: | DIPHTHERIA TOXIN REPRESSOR | | 著者 | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | | 登録日 | 2000-10-25 | | 公開日 | 2001-10-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
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1G3Y
 | | ARG80ALA DTXR | | 分子名称: | DIPHTHERIA TOXIN REPRESSOR, ZINC ION | | 著者 | Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J. | | 登録日 | 2000-10-25 | | 公開日 | 2001-10-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
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1FX7
 | | CRYSTAL STRUCTURE OF THE IRON-DEPENDENT REGULATOR (IDER) FROM MYCOBACTERIUM TUBERCULOSIS | | 分子名称: | COBALT (II) ION, IRON-DEPENDENT REPRESSOR IDER, SULFATE ION | | 著者 | Feese, M.D, Ingason, B.P, Goranson-Siekierke, J, Holmes, R.K, Hol, W.J.G. | | 登録日 | 2000-09-25 | | 公開日 | 2001-03-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the iron-dependent regulator from Mycobacterium tuberculosis at 2.0-A resolution reveals the Src homology domain 3-like fold and metal binding function of the third domain.
J.Biol.Chem., 276, 2001
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1QCB
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1QB5
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3CHB
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2DTR
 | | STRUCTURE OF DIPHTHERIA TOXIN REPRESSOR | | 分子名称: | COBALT (II) ION, DIPHTHERIA TOXIN REPRESSOR, SULFATE ION | | 著者 | Qiu, X, Pohl, E, Hol, W.G. | | 登録日 | 1996-07-26 | | 公開日 | 1997-08-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | High-resolution structure of the diphtheria toxin repressor complexed with cobalt and manganese reveals an SH3-like third domain and suggests a possible role of phosphate as co-corepressor.
Biochemistry, 35, 1996
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1BI2
 | | STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | | 分子名称: | DIPHTHERIA TOXIN REPRESSOR | | 著者 | Pohl, E, Hol, W.G.J. | | 登録日 | 1998-06-21 | | 公開日 | 1999-06-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR.
J.Biol.Chem., 273, 1998
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