3RP7
 
 | | Crystal Structure of Klebsiella pneumoniae HpxO complexed with FAD and uric acid | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, URIC ACID, flavoprotein monooxygenase | | 著者 | Hicks, K.A, O'Leary, S.E, Begley, T.P, Ealick, S.E. | | 登録日 | 2011-04-26 | | 公開日 | 2012-05-16 | | 最終更新日 | 2013-02-06 | | 実験手法 | X-RAY DIFFRACTION (2.042 Å) | | 主引用文献 | Structural and Mechanistic Studies of HpxO, a Novel Flavin Adenine Dinucleotide-Dependent Urate Oxidase from Klebsiella pneumoniae.
Biochemistry, 52, 2013
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3RP6
 | | Crystal Structure of Klebsiella pneumoniae HpxO complexed with FAD | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, flavoprotein monooxygenase | | 著者 | Hicks, K.A, O'Leary, S.E, Begley, T.P, Ealick, S.E. | | 登録日 | 2011-04-26 | | 公開日 | 2012-05-16 | | 最終更新日 | 2013-02-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural and Mechanistic Studies of HpxO, a Novel Flavin Adenine Dinucleotide-Dependent Urate Oxidase from Klebsiella pneumoniae.
Biochemistry, 52, 2013
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3RP8
 | | Crystal Structure of Klebsiella pneumoniae R204Q HpxO complexed with FAD | | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, flavoprotein monooxygenase | | 著者 | Hicks, K.A, O'Leary, S.E, Begley, T.P, Ealick, S.E. | | 登録日 | 2011-04-26 | | 公開日 | 2012-05-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.968 Å) | | 主引用文献 | Structural and Mechanistic Studies of HpxO, a Novel Flavin Adenine Dinucleotide-Dependent Urate Oxidase from Klebsiella pneumoniae.
Biochemistry, 52, 2013
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5EOW
 | | Crystal Structure of 6-Hydroxynicotinic Acid 3-Monooxygenase from Pseudomonas putida KT2440 | | 分子名称: | 6-hydroxynicotinate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Yuen, M.E, Zhen, W, Gerwig, T.J, Story, R.W, Kopp, M, Nakamoto, K, Snider, M.J, Hicks, K.A. | | 登録日 | 2015-11-10 | | 公開日 | 2016-06-08 | | 最終更新日 | 2016-07-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural and Biochemical Characterization of 6-Hydroxynicotinic Acid 3-Monooxygenase, A Novel Decarboxylative Hydroxylase Involved in Aerobic Nicotinate Degradation.
Biochemistry, 55, 2016
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5HFT
 | | Crystal structure of HpxW | | 分子名称: | Gamma-glutamyltranspeptidase | | 著者 | Ealick, S.E, Hicks, K.A. | | 登録日 | 2016-01-07 | | 公開日 | 2016-06-29 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.646 Å) | | 主引用文献 | Biochemical and structural characterization of Klebsiella pneumoniae oxamate amidohydrolase in the uric acid degradation pathway.
Acta Crystallogr D Struct Biol, 72, 2016
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6O9A
 | | Crystal structure of MqnA complexed with 3-hydroxybenzoic acid | | 分子名称: | 3-HYDROXYBENZOIC ACID, ACETATE ION, Chorismate dehydratase | | 著者 | Hicks, K.A, Mahanta, N, Naseem, S, Fedoseyenko, D, Begley, T.P, Ealick, S.E. | | 登録日 | 2019-03-13 | | 公開日 | 2019-04-03 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.326 Å) | | 主引用文献 | Menaquinone Biosynthesis: Biochemical and Structural Studies of Chorismate Dehydratase.
Biochemistry, 58, 2019
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8UIQ
 | | H47Q NicC with 2-mercaptopyridine ligand | | 分子名称: | 2-PYRIDINETHIOL, 6-hydroxynicotinate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Hicks, K.A, Perry, K, Turlington, Z.R, Vaz Ferreira de Macedo, S. | | 登録日 | 2023-10-10 | | 公開日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Ligand bound structure of a 6-hydroxynicotinic acid 3-monooxygenase provides mechanistic insights.
Arch.Biochem.Biophys., 752, 2024
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8UIV
 | | H47Q NicC with bound FAD | | 分子名称: | 6-hydroxynicotinate 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Hicks, K.A, Perry, K. | | 登録日 | 2023-10-10 | | 公開日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.511 Å) | | 主引用文献 | Ligand bound structure of a 6-hydroxynicotinic acid 3-monooxygenase provides mechanistic insights.
Arch.Biochem.Biophys., 752, 2024
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6B2W
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6B10
 | | C. Jejuni Agmatine Deiminase | | 分子名称: | PHOSPHATE ION, POTASSIUM ION, Putative peptidyl-arginine deiminase family protein | | 著者 | Shek, R, Hicks, K.A, French, J.B. | | 登録日 | 2017-09-15 | | 公開日 | 2017-12-13 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Structural and Functional Basis for Targeting Campylobacter jejuni Agmatine Deiminase To Overcome Antibiotic Resistance.
Biochemistry, 56, 2017
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4YWR
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4YL5
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6ASV
 | | E. coli PRPP Synthetase | | 分子名称: | CHLORIDE ION, PHOSPHATE ION, Ribose-phosphate pyrophosphokinase | | 著者 | French, J.B, Zhou, W. | | 登録日 | 2017-08-25 | | 公開日 | 2019-01-23 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Crystal structure of E. coli PRPP synthetase.
BMC Struct. Biol., 19, 2019
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8U7E
 | | Structure of Sts-1 HP domain with rebamipide derivative | | 分子名称: | N-(4-ethylbenzoyl)-3-(2-oxo-1,2-dihydroquinolin-4-yl)-L-alanine, Ubiquitin-associated and SH3 domain-containing protein B | | 著者 | Aziz, F, Dey, R, French, J.B. | | 登録日 | 2023-09-15 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | | 主引用文献 | Rebamipide and Derivatives are Potent, Selective Inhibitors of Histidine Phosphatase Activity of the Suppressor of T Cell Receptor Signaling Proteins.
J.Med.Chem., 67, 2024
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8U5M
 | | Structure of Sts-1 HP domain with rebamipide | | 分子名称: | Rebamipide, Ubiquitin-associated and SH3 domain-containing protein B | | 著者 | Azia, F, Dey, R, French, J.B. | | 登録日 | 2023-09-12 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Rebamipide and Derivatives are Potent, Selective Inhibitors of Histidine Phosphatase Activity of the Suppressor of T Cell Receptor Signaling Proteins.
J.Med.Chem., 67, 2024
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