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5MI8
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BU of 5mi8 by Molmil
Structure of the phosphomimetic mutant of EF-Tu T383E
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACETATE ION, BETA-MERCAPTOETHANOL, ...
著者Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A.
登録日2016-11-27
公開日2017-12-20
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
5MI3
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BU of 5mi3 by Molmil
Structure of phosphorylated translation elongation factor EF-Tu from E. coli
分子名称: Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A.
登録日2016-11-27
公開日2017-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
5MI9
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BU of 5mi9 by Molmil
Structure of the phosphomimetic mutant of the elongation factor EF-Tu T62E
分子名称: Elongation factor Tu 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Talavera, A, Hendrix, J, Versees, W, De Gieter, S, Castro-Roa, D, Jurenas, D, Van Nerom, K, Vandenberk, N, Barth, A, De Greve, H, Hofkens, J, Zenkin, N, Loris, R, Garcia-Pino, A.
登録日2016-11-27
公開日2017-12-20
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors.
Sci Adv, 4, 2018
2F9B
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BU of 2f9b by Molmil
Discovery of Novel Heterocyclic Factor VIIa Inhibitors
分子名称: Coagulation factor VII, Tissue factor, {5-(5-AMINO-1H-PYRROLO[3,2-B]PYRIDIN-2-YL)-6-HYDROXY-3'-NITRO-BIPHENYL-3-YL]-ACETIC ACID
著者Rai, R, Kolesnikov, A, Sprengeler, P.A, Torkelson, S, Ton, T, Katz, B.A, Yu, C, Hendrix, J, Shrader, W.D, Stephens, R, Cabuslay, R, Sanford, E, Young, W.B.
登録日2005-12-05
公開日2006-02-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Discovery of novel heterocyclic factor VIIa inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
6S2U
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BU of 6s2u by Molmil
Structure of the catalytic domain of T. thermophilus Rel in complex with AMP and ppGpp
分子名称: (P)ppGpp synthetase I, SpoT/RelA, ADENOSINE MONOPHOSPHATE, ...
著者Garcia-Pino, A.
登録日2019-06-22
公開日2020-07-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes.
Nat.Chem.Biol., 16, 2020
6S2T
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BU of 6s2t by Molmil
Structure of the N-terminal catalytic region of T. thermophilus Rel bound to ppGpp
分子名称: (P)ppGpp synthetase I, SpoT/RelA, CHLORIDE ION, ...
著者Garcia-Pino, A.
登録日2019-06-22
公開日2020-07-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes.
Nat.Chem.Biol., 16, 2020
6S2V
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BU of 6s2v by Molmil
Structure of the N-terminal catalytic region of T. thermophilus Rel
分子名称: (P)ppGpp synthetase I, SpoT/RelA, CHLORIDE ION, ...
著者Garcia-Pino, A.
登録日2019-06-22
公開日2020-07-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献A nucleotide-switch mechanism mediates opposing catalytic activities of Rel enzymes.
Nat.Chem.Biol., 16, 2020
6ZE1
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BU of 6ze1 by Molmil
human NBD1 of CFTR in complex with nanobody G11a
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, ...
著者Garcia-Pino, A, Govaerts, C, Scholl, D, Sigoillot, M.
登録日2020-06-15
公開日2021-06-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.705 Å)
主引用文献A topological switch in CFTR modulates channel activity and sensitivity to unfolding.
Nat.Chem.Biol., 17, 2021

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