8T3W
 
 | | Structure of Bre1-nucleosome complex - state2 | | 分子名称: | 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ... | | 著者 | Zhao, F, Hicks, C.W, Wolberger, C. | | 登録日 | 2023-06-07 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
|
|
8T3Y
 | | Structure of Bre1-nucleosome complex - state1 | | 分子名称: | 601 DNA Strand 1, 601 DNA Strand 2, E3 ubiquitin-protein ligase BRE1, ... | | 著者 | Zhao, F, Hicks, C.W, Wolberger, C. | | 登録日 | 2023-06-08 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
|
|
8T3T
 | | Structure of Bre1-nucleosome complex - state3 | | 分子名称: | 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ... | | 著者 | Zhao, F, Hicks, C.W, Wolberger, C. | | 登録日 | 2023-06-07 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | | 主引用文献 | Mechanism of histone H2B monoubiquitination by Bre1.
Nat.Struct.Mol.Biol., 30, 2023
|
|
5ZJW
 | | Crystal Structure of PAK4 in complex with inhibitor CZg353 | | 分子名称: | (3Z)-N-[(1S)-2-hydroxy-1-phenylethyl]-3-[(1H-imidazol-2-yl)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-5-carboxamide, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Zhao, F, Li, H. | | 登録日 | 2018-03-22 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | | 主引用文献 | Crystal Structure of PAK4 in complex with inhibitor CZg353
To be published
|
|
6IYV
 | | Crystal sturucture of L,D-transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with ertapenem adduct | | 分子名称: | (2S,3R,4S)-4-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-2-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Zhao, F, Li, D.F, Wang, D.C. | | 登録日 | 2018-12-17 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The 1-beta-methyl group confers a lower affinity of l,d-transpeptidase LdtMt2for ertapenem than for imipenem.
Biochem. Biophys. Res. Commun., 510, 2019
|
|
7FCT
 | |
7XC8
 | | Crystal structure of cotton alpha-like expansin GhEXLA1 | | 分子名称: | Beta-expansin, DI(HYDROXYETHYL)ETHER, GLYCEROL | | 著者 | Zhao, F, Men, S, Xue, Y, Tu, L.L, Yin, P, Zhang, X.L. | | 登録日 | 2022-03-23 | | 公開日 | 2023-05-17 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Crystal structure of cotton alpha-like expansin GhEXLA1
To Be Published
|
|
5XVA
 | | Crystal Structure of PAK4 in complex with inhibitor CZH216 | | 分子名称: | ETHANOL, Serine/threonine-protein kinase PAK 4, [6-chloranyl-4-[(5-methyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]-[(3R)-3-methylpiperazin-1-yl]methanone | | 著者 | Zhao, F, Li, H. | | 登録日 | 2017-06-27 | | 公開日 | 2018-02-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.847 Å) | | 主引用文献 | Structure-Based Design of 6-Chloro-4-aminoquinazoline-2-carboxamide Derivatives as Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors.
J. Med. Chem., 61, 2018
|
|
5XVG
 | | Crystal Structure of PAK4 in complex with inhibitor CZH226 | | 分子名称: | 1,2-ETHANEDIOL, ETHANOL, Serine/threonine-protein kinase PAK 4, ... | | 著者 | Zhao, F, Li, H. | | 登録日 | 2017-06-27 | | 公開日 | 2018-02-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-Based Design of 6-Chloro-4-aminoquinazoline-2-carboxamide Derivatives as Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors.
J. Med. Chem., 61, 2018
|
|
5XVF
 | | Crystal Structure of PAK4 in complex with inhibitor CZH062 | | 分子名称: | 2-(4-azanylpiperidin-1-yl)-6-chloranyl-N-(1-methylimidazol-4-yl)quinazolin-4-amine, Serine/threonine-protein kinase PAK 4 | | 著者 | Zhao, F, Li, H. | | 登録日 | 2017-06-27 | | 公開日 | 2018-02-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.655 Å) | | 主引用文献 | Structure-Based Design of 6-Chloro-4-aminoquinazoline-2-carboxamide Derivatives as Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors.
J. Med. Chem., 61, 2018
|
|
8HAW
 | | An auto-activation mechanism of plant non-specific phospholipase C | | 分子名称: | CALCIUM ION, GLYCEROL, Non-specific phospholipase C4, ... | | 著者 | Zhao, F, Fan, R.Y, Guan, Z.Y, Guo, L, Yin, P. | | 登録日 | 2022-10-26 | | 公開日 | 2023-01-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Insights into the mechanism of phospholipid hydrolysis by plant non-specific phospholipase C.
Nat Commun, 14, 2023
|
|
8HAV
 | | An auto-activation mechanism of plant non-specific phospholipase C | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Non-specific phospholipase C4 | | 著者 | Zhao, F, Fan, R.Y, Guan, Z.Y, Guo, L, Yin, P. | | 登録日 | 2022-10-26 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Insights into the mechanism of phospholipid hydrolysis by plant non-specific phospholipase C.
Nat Commun, 14, 2023
|
|
1ZX7
 | | Molecular Recognition of RNA by Neomycin and a Restricted Neomycin Derivative | | 分子名称: | 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*AP*CP*C)-3', 5'-R(*GP*UP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*CP*GP*G)-3' | | 著者 | Zhao, Q, Zhao, F, Blount, K.F, Han, Q, Tor, Y, Hermann, T. | | 登録日 | 2005-06-07 | | 公開日 | 2005-09-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Molecular recognition of RNA by neomycin and a restricted neomycin derivative
Angew.Chem.Int.Ed.Engl., 44, 2005
|
|
2A04
 | | Molecular Recognition of RNA by Neomycin and a Restricted Neomycin Derivative | | 分子名称: | 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*AP*CP*C)-3', 5'-R(*GP*UP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*CP*GP*G)-3', MAGNESIUM ION, ... | | 著者 | Zhao, Q, Zhao, F, Blount, K.F, Han, Q, Tor, Y, Hermann, T. | | 登録日 | 2005-06-15 | | 公開日 | 2005-09-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Molecular recognition of RNA by neomycin and a restricted neomycin derivative
Angew.Chem.Int.Ed.Engl., 44, 2005
|
|
1ZZ5
 | | Molecular Recognition of RNA by Neomycin and a Restricted Neomycin Derivative | | 分子名称: | 13,15-DIAMINO-2-(AMINOMETHYL)-3,4,9,12-TETRAHYDROXYHEXADECAHYDRO-2H-7,10-EPOXYPYRANO[2,3-B][1,10,4]BENZODIOXAZACYCLODODECIN-8-YL 2,6-DIAMINO-2,6-DIDEOXYHEXOPYRANOSIDE, 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*AP*CP*C)-3', 5'-R(*GP*UP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*CP*GP*G)-3', ... | | 著者 | Zhao, Q, Zhao, F, Blount, K.F, Han, Q, Tor, Y, Hermann, T. | | 登録日 | 2005-06-13 | | 公開日 | 2005-09-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Molecular recognition of RNA by neomycin and a restricted neomycin derivative
Angew.Chem.Int.Ed.Engl., 44, 2005
|
|
6IYW
 | | Crystal sturucture of L,D-transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with Imipenem adduct | | 分子名称: | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, GLYCEROL, L,D-transpeptidase 2 | | 著者 | Li, D.F, Zhao, F, Wang, D.C. | | 登録日 | 2018-12-17 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The 1-beta-methyl group confers a lower affinity of l,d-transpeptidase LdtMt2 for ertapenem than for imipenem.
Biochem. Biophys. Res. Commun., 510, 2019
|
|
4FMD
 | | EspG-Rab1 complex structure at 3.05 A | | 分子名称: | ALUMINUM FLUORIDE, DI(HYDROXYETHYL)ETHER, EspG protein, ... | | 著者 | Shao, F, Zhu, Y. | | 登録日 | 2012-06-16 | | 公開日 | 2012-09-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses.
Cell(Cambridge,Mass.), 150, 2012
|
|
4FMC
 | | EspG-Rab1 complex | | 分子名称: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Shao, F, Zhu, Y. | | 登録日 | 2012-06-16 | | 公開日 | 2012-09-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses.
Cell(Cambridge,Mass.), 150, 2012
|
|
4FME
 | | EspG-Rab1-Arf6 complex | | 分子名称: | ADP-ribosylation factor 6, ALUMINUM FLUORIDE, EspG protein, ... | | 著者 | Shao, F, Zhu, Y. | | 登録日 | 2012-06-16 | | 公開日 | 2012-09-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | | 主引用文献 | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses.
Cell(Cambridge,Mass.), 150, 2012
|
|
4FMB
 | | VirA-Rab1 complex structure | | 分子名称: | ALUMINUM FLUORIDE, Cysteine protease-like virA, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Shao, F, Zhu, Y. | | 登録日 | 2012-06-16 | | 公開日 | 2012-09-05 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses.
Cell(Cambridge,Mass.), 150, 2012
|
|
4FMA
 | | EspG structure | | 分子名称: | ACETIC ACID, EspG protein, FORMIC ACID, ... | | 著者 | Shao, F, Zhu, Y, Hu, L. | | 登録日 | 2012-06-16 | | 公開日 | 2012-09-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses.
Cell(Cambridge,Mass.), 150, 2012
|
|
7XJR
 | | MLXase AlXyn26A | | 分子名称: | AlXyn26A | | 著者 | Zhang, Y.Z, Chen, X.L, Zhao, F, Yu, C.M. | | 登録日 | 2022-04-18 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | A novel class of xylanases specifically degrade marine red algal beta 1,3/1,4-mixed-linkage xylan.
J.Biol.Chem., 299, 2023
|
|
7XS3
 | | AlXyn26A E243A-X3X4X | | 分子名称: | AlXyn26A E243A-X3X4X, beta-D-xylopyranose-(1-3)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose | | 著者 | Zhang, Y.Z, Chen, X.L, Zhao, F, Yu, C.M. | | 登録日 | 2022-05-12 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A novel class of xylanases specifically degrade marine red algal beta 1,3/1,4-mixed-linkage xylan.
J.Biol.Chem., 299, 2023
|
|
6LKA
 | | Crystal Structure of EV71-3C protease with a Novel Macrocyclic Compounds | | 分子名称: | 3C proteinase, ~{N}-[(2~{S})-1-[[(2~{S},3~{S},6~{S},7~{Z},12~{E})-4,9-bis(oxidanylidene)-6-[[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]methyl]-2-phenyl-1,10-dioxa-5-azacyclopentadeca-7,12-dien-3-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]-5-methyl-1,2-oxazole-3-carboxamide | | 著者 | Li, P, Wu, S.Q, Xiao, T.Y.C, Li, Y.L, Su, Z.M, Hao, F, Hu, G.P, Hu, J, Lin, F.S, Chen, X.S, Gu, Z.X, He, H.Y, Li, J, Chen, S.H. | | 登録日 | 2019-12-18 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.033 Å) | | 主引用文献 | Design, synthesis, and evaluation of a novel macrocyclic anti-EV71 agent.
Bioorg.Med.Chem., 28, 2020
|
|
6IHK
 | | Structure of MMPA CoA ligase in complex with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, AMP-binding domain protein | | 著者 | Shao, X, Cao, H.Y, Wang, P, Li, C.Y, Zhao, F, Peng, M, Chen, X.L, Zhang, Y.Z. | | 登録日 | 2018-09-30 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Mechanistic insight into 3-methylmercaptopropionate metabolism and kinetical regulation of demethylation pathway in marine dimethylsulfoniopropionate-catabolizing bacteria.
Mol.Microbiol., 111, 2019
|
|
