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8WYF
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BU of 8wyf by Molmil
Cryo-EM structure of DSR2-DSAD1-NAD+ (partial) complex
分子名称: Bacillus phage SPbeta DSAD1 protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2 family protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8WYC
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BU of 8wyc by Molmil
Cryo-EM structure of DSR2 (H171A)-tube-NAD+ (partial) complex
分子名称: Bacillus phage SPR Tube protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2-like domain-containing protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8WYD
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BU of 8wyd by Molmil
Cryo-EM structure of DSR2-DSAD1 complex
分子名称: Bacillus phage SPbeta DSAD1 protein, SIR2 family protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.56 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8WYE
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BU of 8wye by Molmil
Cryo-EM structure of DSR2-DSAD1 (partial) complex
分子名称: Bacillus phage SPbeta DSAD1 protein, SIR2 family protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.49 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8WY9
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BU of 8wy9 by Molmil
Cryo-EM structure of DSR2 apo (partial) complex
分子名称: SIR2 family protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.57 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8WYA
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BU of 8wya by Molmil
Cryo-EM structure of DSR2-tube complex
分子名称: Bacillus phage SPbeta tube protein, SIR2 family protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8WYB
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BU of 8wyb by Molmil
Cryo-EM structure of DSR2 (H171A)-tube-NAD+ complex
分子名称: Bacillus phage SPR Tube protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2-like domain-containing protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8WY8
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BU of 8wy8 by Molmil
Cryo-EM structure of DSR2 apo complex
分子名称: SIR2 family protein
著者Zhang, J.T, Jia, N, Liu, X.Y.
登録日2023-10-30
公開日2024-04-10
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Nat Commun, 15, 2024
8IFM
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BU of 8ifm by Molmil
Cryo-EM structure of tetrameric SPARTA gRNA-ssDNA target complex in state 2
分子名称: MAGNESIUM ION, Piwi domain-containing protein, TIR domain-containing protein, ...
著者Zhang, J.T, Jia, N.
登録日2023-02-18
公開日2024-01-17
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat.Chem.Biol., 20, 2024
8IFL
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BU of 8ifl by Molmil
Cryo-EM structure of tetrameric SPARTA gRNA-ssDNA target complex in state 1
分子名称: MAGNESIUM ION, Piwi domain-containing protein, TIR domain-containing protein, ...
著者Zhang, J.T, Jia, N.
登録日2023-02-18
公開日2024-01-17
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat.Chem.Biol., 20, 2024
8IFK
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BU of 8ifk by Molmil
Cryo-EM structure of monomeric SPARTA gRNA-ssDNA target complex
分子名称: MAGNESIUM ION, Piwi domain-containing protein, TIR domain-containing protein, ...
著者Zhang, J.T, Jia, N.
登録日2023-02-18
公開日2024-01-17
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.54 Å)
主引用文献Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat.Chem.Biol., 20, 2024
7ETT
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BU of 7ett by Molmil
The FK1 domain of FKBP51 in complex with peptide-inhibitor hit QFPFV
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP5, peptide-inhibitor hit
著者Han, J.T, Zhu, Y.C, Pan, D.B, Xue, H.X, Wang, S, Liu, H.X, He, Y.X, Yao, X.J.
登録日2021-05-14
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography.
Comput Struct Biotechnol J, 19, 2021
7ETV
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BU of 7etv by Molmil
The FK1 domain of FKBP51 in complex with peptide-inhibitor hit DFPFV
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP5, peptide-inhibitor hit
著者Han, J.T, Zhu, Y.C, Pan, D.B, Xue, H.X, Wang, S, Liu, H.X, He, Y.X, Yao, X.J.
登録日2021-05-14
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography.
Comput Struct Biotechnol J, 19, 2021
7ETU
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BU of 7etu by Molmil
The FK1 domain of FKBP51 in complex with peptide-inhibitor hit SFPFT
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP5, peptide-inhibitor hit
著者Han, J.T, Zhu, Y.C, Pan, D.B, Xue, H.X, Wang, S, Liu, H.X, He, Y.X, Yao, X.J.
登録日2021-05-14
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Discovery of pentapeptide-inhibitor hits targeting FKBP51 by combining computational modeling and X-ray crystallography.
Comput Struct Biotechnol J, 19, 2021
8K34
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BU of 8k34 by Molmil
Cryo-EM structure of SPARTA gRNA binary complex
分子名称: MAGNESIUM ION, Piwi domain-containing protein, RNA (5'-R(P*AP*AP*AP*CP*GP*GP*CP*UP*CP*UP*AP*AP*UP*CP*UP*AP*UP*UP*AP*GP*U)-3'), ...
著者Zhang, J.T, Jia, N.
登録日2023-07-14
公開日2024-01-17
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system.
Nat.Chem.Biol., 20, 2024
7EEA
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BU of 7eea by Molmil
Cyanophage Pam1 tailspike receptor-binding domain
分子名称: Short-tailed cyanophage tailspike receptor-binding domain
著者Zhang, J.T, Jiang, Y.L, Zhou, C.Z.
登録日2021-03-18
公開日2021-10-20
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.671 Å)
主引用文献Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1.
Structure, 30, 2022
7EEQ
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BU of 7eeq by Molmil
Cyanophage Pam1 tail machine
分子名称: Needle head proteins, Tailspike head-binding domain
著者Zhang, J.T, Jiang, Y.L, Zhou, C.Z.
登録日2021-03-19
公開日2021-10-20
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1.
Structure, 30, 2022
7EEP
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BU of 7eep by Molmil
Cyanophage Pam1 portal-adaptor complex
分子名称: Pam1 adaptor proteins, Pam1 portal proteins
著者Zhang, J.T, Jiang, Y.L, Zhou, C.Z.
登録日2021-03-19
公開日2021-10-20
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1.
Structure, 30, 2022
7EEL
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BU of 7eel by Molmil
Cyanophage Pam1 capsid asymmetric unit
分子名称: Cement (decoration) proteins, Major capsid proteins
著者Zhang, J.T, Jiang, Y.L, Zhou, C.Z.
登録日2021-03-19
公開日2021-10-20
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1.
Structure, 30, 2022
5XEY
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BU of 5xey by Molmil
Discovery and structural analysis of a phloretin hydrolase from the opportunistic pathogen Mycobacterium abscessus
分子名称: 1-[2,4,6-tris(oxidanyl)phenyl]ethanone, phloretin hydrolase
著者He, Y.X, Han, J.T, Jia, W.J, Zhang, Z.
登録日2017-04-06
公開日2018-05-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Discovery and structural analysis of a phloretin hydrolase from the opportunistic human pathogen Mycobacterium abscessus.
FEBS J., 2019
5XE5
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BU of 5xe5 by Molmil
Discovery and structural analysis of a phloretin hydrolase from the opportunistic pathogen Mycobacterium abscessus
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, phloretin hydrolase
著者He, Y.X, Han, J.T, Jia, W.J, Zhang, Z.
登録日2017-04-01
公開日2018-05-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Discovery and structural analysis of a phloretin hydrolase from the opportunistic human pathogen Mycobacterium abscessus.
FEBS J., 2019
7XEX
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BU of 7xex by Molmil
Crystal strucutre of apoCasDinG
分子名称: CasDinG
著者Zhang, J.T, Cui, N, Liu, Y.R, Huang, H.D, Jia, N.
登録日2022-03-31
公開日2023-07-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XF0
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BU of 7xf0 by Molmil
Crystal strucutre of CasDinG in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CasDinG
著者Zhang, J.T, Cui, N, Liu, Y.R, Huang, H.D, Jia, N.
登録日2022-03-31
公開日2023-07-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XF1
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BU of 7xf1 by Molmil
Crystal strucutre of apoCasDinG in complex with ssDNA
分子名称: CasDinG, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3')
著者Zhang, J.T, Cui, N, Liu, Y.R, Huang, H.D, Jia, N.
登録日2022-03-31
公開日2023-07-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment.
Mol.Cell, 83, 2023
7XG1
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BU of 7xg1 by Molmil
CryoEM structure of type IV-A Csf-crRNA binary complex
分子名称: Csf1, Csf2, Csf3, ...
著者Zhang, J.T, Cui, N, Huang, H.D, Jia, N.
登録日2022-04-02
公開日2023-08-02
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment
Mol.Cell, 83, 2023

 

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