4XLI
 
 | | Crystal structure of Abl2/Arg kinase in complex with dasatinib | | 分子名称: | N-(2-CHLORO-6-METHYLPHENYL)-2-({6-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]-2-METHYLPYRIMIDIN-4-YL}AMINO)-1,3-THIAZOLE-5-CARBOXAMIDE, Non-specific protein-tyrosine kinase, ZINC ION | | 著者 | Ha, B.H, Boggon, T.J. | | 登録日 | 2015-01-13 | | 公開日 | 2015-04-01 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the ABL2/ARG kinase in complex with dasatinib.
Acta Crystallogr.,Sect.F, 71, 2015
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6BHC
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7S47
 | | Integrin beta5(743-774)-linker-PAK4cat(D440N/S474E) | | 分子名称: | Integrin beta-5, Isoform 2 of Serine/threonine-protein kinase PAK 4 chimera, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Ha, B.H, Boggon, T.J. | | 登録日 | 2021-09-08 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular basis for integrin adhesion receptor binding to p21-activated kinase 4 (PAK4)
Commun Biol, 5, 2022
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7S46
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7S48
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2Z84
 | | Insights from crystal and solution structures of mouse UfSP1 | | 分子名称: | Ufm1-specific protease 1 | | 著者 | Ha, B.H, Ahn, H.C, Kang, S.H, Tanaka, K, Chung, C.H, Kim, E.E. | | 登録日 | 2007-08-30 | | 公開日 | 2008-03-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis for Ufm1 processing by UfSP1
J. Biol. Chem., 283, 2008
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5UPL
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5UPK
 | | CDC42 binds PAK4 via an extended GTPase-effector interface - 3 peptide: PAK4cat, PAK4-N45, CDC42 | | 分子名称: | Cell division control protein 42 homolog, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Ha, B.H, Boggon, T.J. | | 登録日 | 2017-02-03 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | CDC42 binds PAK4 via an extended GTPase-effector interface.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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3OQC
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4FIH
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4FIE
 | | Full-length human PAK4 | | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase PAK 4 | | 著者 | Ha, B.H, Boggon, T.J. | | 登録日 | 2012-06-08 | | 公開日 | 2012-09-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4FIF
 | | Catalytic domain of human PAK4 with RPKPLVDP peptide | | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase PAK 4 | | 著者 | Ha, B.H, Boggon, T.J. | | 登録日 | 2012-06-08 | | 公開日 | 2012-09-12 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4FII
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4FIJ
 | | Catalytic domain of human PAK4 | | 分子名称: | Serine/threonine-protein kinase PAK 4 | | 著者 | Ha, B.H, Boggon, T.J. | | 登録日 | 2012-06-08 | | 公開日 | 2012-09-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4FIG
 | | Catalytic domain of human PAK4 | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase PAK 4 | | 著者 | Ha, B.H, Boggon, T.J. | | 登録日 | 2012-06-08 | | 公開日 | 2012-09-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate.
Proc.Natl.Acad.Sci.USA, 109, 2012
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3TH5
 | | Crystal structure of wild-type RAC1 | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1 | | 著者 | Ha, B.H, Boggon, T.J. | | 登録日 | 2011-08-18 | | 公開日 | 2012-07-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Nat.Genet., 44, 2012
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5GVJ
 | | Structure of FabK (M276A) mutant from Thermotoga maritima | | 分子名称: | Enoyl-[acyl-carrier-protein] reductase [FMN], SODIUM ION | | 著者 | Kim, E.E, Shin, S.C, Ha, B.H, Moon, J.H. | | 登録日 | 2016-09-06 | | 公開日 | 2017-04-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and biochemical characterization of FabK from Thermotoga maritima.
Biochem. Biophys. Res. Commun., 482, 2017
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5GVH
 | | Structure of FabK from Thermotoga maritima | | 分子名称: | Enoyl-[acyl-carrier-protein] reductase [FMN], FLAVIN MONONUCLEOTIDE, SODIUM ION | | 著者 | Kim, E.E, Shin, S.C, Ha, B.H, Moon, J.H. | | 登録日 | 2016-09-05 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.294 Å) | | 主引用文献 | Structural and biochemical characterization of FabK from Thermotoga maritima.
Biochem. Biophys. Res. Commun., 482, 2017
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3SBE
 | | Crystal structure of RAC1 P29S mutant | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1 | | 著者 | Ha, B.H, Boggon, T.J. | | 登録日 | 2011-06-03 | | 公開日 | 2012-07-18 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Nat.Genet., 44, 2012
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3SBD
 | | Crystal structure of RAC1 P29S mutant | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1 | | 著者 | Ha, B.H, Boggon, T.J. | | 登録日 | 2011-06-03 | | 公開日 | 2012-07-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.
Nat.Genet., 44, 2012
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4JDH
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4JDK
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4JDI
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4JDJ
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4GZM
 | | Crystal structure of RAC1 F28L mutant | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1 | | 著者 | Ha, B.H, Boggon, T.J. | | 登録日 | 2012-09-06 | | 公開日 | 2012-12-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | RAC1P29S is a spontaneously activating cancer-associated GTPase.
Proc.Natl.Acad.Sci.USA, 110, 2013
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