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2V8N
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BU of 2v8n by Molmil
Wild-type Structure of Lactose Permease
分子名称: LACTOSE PERMEASE
著者Guan, L, Mirza, O, Verner, G, Iwata, S, Kaback, H.R.
登録日2007-08-09
公開日2007-09-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structural Determination of Wild-Type Lactose Permease.
Proc.Natl.Acad.Sci.USA, 104, 2007
7L16
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BU of 7l16 by Molmil
Crystal structure of sugar-bound melibiose permease MelB
分子名称: Melibiose carrier protein, dodecyl 6-O-alpha-D-galactopyranosyl-beta-D-glucopyranoside
著者Guan, L.
登録日2020-12-14
公開日2021-08-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献X-ray crystallography reveals molecular recognition mechanism for sugar binding in a melibiose transporter MelB.
Commun Biol, 4, 2021
7L17
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Crystal structure of sugar-bound melibiose permease MelB
分子名称: 4-nitrophenyl alpha-D-galactopyranoside, Melibiose carrier protein
著者Guan, L.
登録日2020-12-14
公開日2021-08-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献X-ray crystallography reveals molecular recognition mechanism for sugar binding in a melibiose transporter MelB.
Commun Biol, 4, 2021
8FQ9
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BU of 8fq9 by Molmil
Crystal structure of a ligand-bound cation-site mutant D55C of a melibiose transporter
分子名称: Melibiose permease, PENTAETHYLENE GLYCOL, dodecyl 6-O-alpha-D-galactopyranosyl-beta-D-glucopyranoside
著者Guan, L.
登録日2023-01-05
公開日2024-06-05
最終更新日2024-12-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Distinct roles of the major binding residues in the cation-binding pocket of the melibiose transporter MelB.
J.Biol.Chem., 300, 2024
8FRH
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BU of 8frh by Molmil
Apo structure of D59C mutant of a melibiose transporter
分子名称: Melibiose permease, PENTAETHYLENE GLYCOL
著者Guan, L, Hariharan, P.
登録日2023-01-06
公開日2024-06-05
最終更新日2024-12-18
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Distinct roles of the major binding residues in the cation-binding pocket of the melibiose transporter MelB.
J.Biol.Chem., 300, 2024
8T60
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BU of 8t60 by Molmil
CryoEM structure of an inward-facing MelBSt at a Na(+)-bound and sugar low-affinity conformation
分子名称: Melibiose permease, NabFab_H Chain, NabFab_L Chain, ...
著者Guan, L.
登録日2023-06-14
公開日2024-02-28
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Mobile barrier mechanisms for Na + -coupled symport in an MFS sugar transporter.
Elife, 12, 2024
2Y5Y
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BU of 2y5y by Molmil
Crystal structure of LacY in complex with an affinity inactivator
分子名称: 2-sulfanylethyl beta-D-galactopyranoside, BARIUM ION, LACTOSE PERMEASE
著者Chaptal, V, Kwon, S, Sawaya, M.R, Guan, L, Kaback, H.R, Abramson, J.
登録日2011-01-19
公開日2011-06-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.38 Å)
主引用文献Crystal Structure of Lactose Permease in Complex with an Affinity Inactivator Yields Unique Insight Into Sugar Recognition.
Proc.Natl.Acad.Sci.USA, 108, 2011
6NFV
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BU of 6nfv by Molmil
Structure of the KcsA-G77C mutant or the 2,4-ion bound configuration of a K+ channel selectivity filter.
分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, NONAN-1-OL, POTASSIUM ION, ...
著者Tilegenova, C, Cortes, D.M, Jahovic, N, Hardy, E, Parameswaran, H, Guan, L, Cuello, L.G.
登録日2018-12-20
公開日2019-08-07
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Structure, function, and ion-binding properties of a K+channel stabilized in the 2,4-ion-bound configuration.
Proc.Natl.Acad.Sci.USA, 116, 2019
6NFU
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BU of 6nfu by Molmil
Structure of the KcsA-G77A mutant or the 2,4-ion bound configuration of a K+ channel selectivity filter.
分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, NONAN-1-OL, POTASSIUM ION, ...
著者Tilegenova, C, Cortes, D.M, Jahovic, N, Hardy, E, Parameswaran, H, Guan, L, Cuello, L.G.
登録日2018-12-20
公開日2019-08-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structure, function, and ion-binding properties of a K+channel stabilized in the 2,4-ion-bound configuration.
Proc.Natl.Acad.Sci.USA, 116, 2019
6PA0
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BU of 6pa0 by Molmil
Structure of the G77A mutant in Sodium Chloride
分子名称: Antibody HEAVY fragment, Antibody LIGHT fragment, DIACYL GLYCEROL, ...
著者Cuello, L.G, Guan, L.
登録日2019-06-11
公開日2019-08-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure, function, and ion-binding properties of a K+channel stabilized in the 2,4-ion-bound configuration.
Proc.Natl.Acad.Sci.USA, 116, 2019
2CFQ
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BU of 2cfq by Molmil
Sugar Free Lactose Permease at neutral pH
分子名称: LACTOSE PERMEASE, MERCURY (II) ION
著者Mirza, O, Guan, L, Verner, G, Iwata, S, Kaback, H.R.
登録日2006-02-22
公開日2006-03-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural Evidence for Induced Fit and a Mechanism for Sugar/H(+) Symport in Lacy.
Embo J., 25, 2006
2CFP
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BU of 2cfp by Molmil
Sugar Free Lactose Permease at acidic pH
分子名称: LACTOSE PERMEASE, MERCURY (II) ION
著者Mirza, O, Guan, L, Verner, G, Iwata, S, Kaback, H.R.
登録日2006-02-22
公開日2006-03-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural Evidence for Induced Fit and a Mechanism for Sugar/H(+) Symport in Lacy.
Embo J., 25, 2006
4M64
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BU of 4m64 by Molmil
3D crystal structure of Na+/melibiose symporter of Salmonella typhimurium
分子名称: Melibiose carrier protein
著者Ethayathulla, A.S, Guan, L.
登録日2013-08-08
公開日2014-01-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Structure-based mechanism for Na(+)/melibiose symport by MelB.
Nat Commun, 5, 2014
4O60
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BU of 4o60 by Molmil
Structure of ankyrin repeat protein
分子名称: ANK-N5C-317
著者Ethayathulla, A.S, Guan, L.
登録日2013-12-20
公開日2015-03-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献A transcription blocker isolated from a designed repeat protein combinatorial library by in vivo functional screen.
Sci Rep, 5, 2015
8XW5
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BU of 8xw5 by Molmil
Cryo-EM structure of the aspartate:alanine antiporter AspT mutant L60C
分子名称: Aspartate/alanine antiporter
著者Nanatani, K, Kanno, R, Kawabata, T, Watanabe, S, Hidaka, M, Yamanaka, T, Toda, K, Fujiki, T, Kunii, K, Miyamoto, A, Chiba, F, Ogasawara, S, Murata, T, Humbel, B.M, Inaba, K, Mitsuoka, K, Guan, L, Abe, K, Yamamoto, M, Koshiba, S.
登録日2024-01-16
公開日2025-01-22
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Cryo-EM structure and molecular mechanism of the aspartate:alanine antiporter AspT from Tetragenococcus halophilus
To Be Published
8Y1X
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BU of 8y1x by Molmil
Cryo-EM structure of the aspartate:alanine antiporter AspT WT
分子名称: ASPARTIC ACID, Aspartate/alanine antiporter
著者Nanatani, K, Kanno, R, Kawabata, T, Watanabe, S, Hidaka, M, Yamanaka, T, Toda, K, Fujiki, T, Kunii, K, Miyamoto, A, Chiba, F, Ogasawara, S, Murata, T, Humbel, B.M, Inaba, K, Mitsuoka, K, Guan, L, Abe, K, Yamamoto, M, Koshiba, S.
登録日2024-01-25
公開日2025-01-29
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Cryo-EM structure and molecular mechanism of the aspartate:alanine antiporter AspT from Tetragenococcus halophilus
To Be Published
4QFV
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BU of 4qfv by Molmil
Crystal structure of a unique ankyrin
分子名称: ACETATE ION, ANK-N5C-281
著者Ethayathulla, A.S, Tikhonova, E.B, Guan, L.
登録日2014-05-21
公開日2015-05-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献A transcription blocker isolated from a designed repeat protein combinatorial library by in vivo functional screen.
Sci Rep, 5, 2015
3WI7
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BU of 3wi7 by Molmil
Crystal Structure of the Novel Haloalkane Dehalogenase DatA from Agrobacterium tumefaciens C58
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Haloalkane dehalogenase
著者Guan, L.J, Yabuki, H, Okai, M, Ohtsuka, J, Tanokura, M.
登録日2013-09-06
公開日2014-07-23
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the novel haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58 reveals a special halide-stabilizing pair and enantioselectivity mechanism.
Appl.Microbiol.Biotechnol., 98, 2014
3WIB
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BU of 3wib by Molmil
Crystal structure of Y109W Mutant Haloalkane Dehalogenase DatA from Agrobacterium tumefaciens C58
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Haloalkane dehalogenase
著者Guan, L.J, Yabuki, H, Okai, M, Ohtsuka, J, Tanokura, M.
登録日2013-09-09
公開日2014-07-23
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the novel haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58 reveals a special halide-stabilizing pair and enantioselectivity mechanism.
Appl.Microbiol.Biotechnol., 98, 2014
5B7J
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BU of 5b7j by Molmil
Structure model of Sap1-DNA complex
分子名称: DNA (5'-D(*AP*AP*TP*AP*TP*TP*GP*TP*TP*TP*TP*G)-3'), DNA (5'-D(*CP*AP*AP*AP*AP*CP*AP*AP*TP*AP*TP*T)-3'), Switch-activating protein 1
著者Jin, C, Hu, Y, Ding, J, Zhang, Y.
登録日2016-06-07
公開日2017-02-22
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Sap1 is a replication-initiation factor essential for the assembly of pre-replicative complex in the fission yeast Schizosaccharomyces pombe
J. Biol. Chem., 292, 2017
5JDK
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BU of 5jdk by Molmil
Crystal structure of the DNA binding domain of Sap1 in fission yeast S.pombe
分子名称: GLYCEROL, Switch-activating protein 1
著者He, P, Wang, T.
登録日2016-04-17
公開日2017-02-22
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (0.998 Å)
主引用文献Sap1 is a replication-initiation factor essential for the assembly of pre-replicative complex in the fission yeast Schizosaccharomyces pombe.
J. Biol. Chem., 292, 2017
4K27
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BU of 4k27 by Molmil
Myotonic Dystrophy Type 2 RNA: Structural Studies and Designed Small Molecules that Modulate RNA Function
分子名称: CHLORIDE ION, MAGNESIUM ION, Myotonic Dystrophy Type 2 RNA
著者Park, H, Lohman, J, Disney, M.D.
登録日2013-04-08
公開日2013-11-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Myotonic Dystrophy Type 2 RNA: Structural Studies and Designed Small Molecules that Modulate RNA Function
ACS CHEM.BIOL., 2013
8IXZ
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BU of 8ixz by Molmil
Structure of Acb2 complexed with 3',2'-cGAMP
分子名称: 3'2'-cGAMP, p26
著者Cao, X.L, Xiao, Y, Feng, Y.
登録日2023-04-03
公開日2024-02-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides.
Mol.Cell, 84, 2024
8IY1
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Structure of Acb2 complexed with cAAG
分子名称: GUANOSINE-3'-MONOPHOSPHATE, [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate, p26
著者Cao, X.L, Xiao, Y, Feng, Y.
登録日2023-04-03
公開日2024-02-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides.
Mol.Cell, 84, 2024
8IY0
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Structure of Acb2 complexed with cAAA
分子名称: [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] dihydrogen phosphate, p26
著者Cao, X.L, Xiao, Y, Feng, Y.
登録日2023-04-03
公開日2024-02-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Phage anti-CBASS protein simultaneously sequesters cyclic trinucleotides and dinucleotides.
Mol.Cell, 84, 2024

 

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