7R8V
 
 | | Cryo-EM structure of the ADP state actin filament | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Gong, R, Espinosa de los Reyes, S, Reynolds, M.J, Gurel, P, Alushin, G.M. | | 登録日 | 2021-06-27 | | 公開日 | 2021-07-28 | | 最終更新日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | | 主引用文献 | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.
Sci Adv, 8, 2022
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7RB9
 | | Cryo-EM structure of the rigor state Jordan myosin-15-F-actin complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Gong, R, Reynolds, M.J, Gurel, P, Alushin, G.M. | | 登録日 | 2021-07-05 | | 公開日 | 2021-07-28 | | 最終更新日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (3.76 Å) | | 主引用文献 | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.
Sci Adv, 8, 2022
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7R91
 | | cryo-EM structure of the rigor state wild type myosin-15-F-actin complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Gong, R, Reynolds, M.J, Gurel, P, Alushin, G.M. | | 登録日 | 2021-06-28 | | 公開日 | 2021-07-28 | | 最終更新日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | | 主引用文献 | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.
Sci Adv, 8, 2022
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7RB8
 | | cryo-EM structure of the ADP state wild type myosin-15-F-actin complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Gong, R, Reynolds, M.J, Gurel, P, Alushin, G.M. | | 登録日 | 2021-07-05 | | 公開日 | 2021-07-28 | | 最終更新日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | | 主引用文献 | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.
Sci Adv, 8, 2022
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3R7W
 | | Crystal Structure of Gtr1p-Gtr2p complex | | 分子名称: | GTP-binding protein GTR1, GTP-binding protein GTR2, MAGNESIUM ION, ... | | 著者 | Gong, R, Li, L, Liu, Y, Wang, P, Yang, H, Wang, L, Cheng, J, Guan, K.L, Xu, Y. | | 登録日 | 2011-03-23 | | 公開日 | 2011-08-24 | | 最終更新日 | 2013-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.773 Å) | | 主引用文献 | Crystal structure of the Gtr1p-Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation
Genes Dev., 25, 2011
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6KBH
 | | Crystal structure of an intact type IV self-sufficient cytochrome P450 monooxygenase | | 分子名称: | Cytochrome P450 monooxygenase, FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, ... | | 著者 | Gong, R, Wu, L.J, Zhang, Y, Liu, Z, Dou, S, Zhang, R.G, Xu, J.H, Tang, C, Zhou, J.H. | | 登録日 | 2019-06-25 | | 公開日 | 2020-07-01 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of an intact type IV self-sufficient cytochrome P450 monooxygenase
To Be Published
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7UDT
 | | cryo-EM structure of the rigor state wild type myosin-15-F-actin complex (symmetry expansion and re-centering) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Gong, R, Reynolds, M.J, Alushin, G.M. | | 登録日 | 2022-03-20 | | 公開日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.
Sci Adv, 8, 2022
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7UDU
 | | cryo-EM structure of the ADP state wild type myosin-15-F-actin complex (symmetry expansion and re-centering) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Gong, R, Reynolds, M.J, Alushin, G.M. | | 登録日 | 2022-03-20 | | 公開日 | 2022-08-03 | | 実験手法 | ELECTRON MICROSCOPY (4.15 Å) | | 主引用文献 | Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.
Sci Adv, 8, 2022
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7KCH
 | | Myosin XI-F-actin complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Gong, R, Alushin, G.M. | | 登録日 | 2020-10-05 | | 公開日 | 2021-01-13 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.33 Å) | | 主引用文献 | Optical control of fast and processive engineered myosins in vitro and in living cells.
Nat.Chem.Biol., 17, 2021
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5IAY
 | | NMR structure of UHRF1 Tandem Tudor Domains in a complex with Spacer peptide | | 分子名称: | E3 ubiquitin-protein ligase UHRF1, Spacer | | 著者 | Fang, J, Cheng, J, Wang, J, Zhang, Q, Liu, M, Gong, R, Wang, P, Zhang, X, Feng, Y, Lan, W, Gong, Z, Tang, C, Wong, J, Yang, H, Cao, C, Xu, Y. | | 登録日 | 2016-02-22 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition
Nat Commun, 7, 2016
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4YOC
 | | Crystal Structure of human DNMT1 and USP7/HAUSP complex | | 分子名称: | DNA (cytosine-5)-methyltransferase 1, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION | | 著者 | Cheng, J, Yang, H, Fang, J, Gong, R, Wang, P, Li, Z, Xu, Y. | | 登録日 | 2015-03-11 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.916 Å) | | 主引用文献 | Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation.
Nat Commun, 6, 2015
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5C56
 | | Crystal structure of USP7/HAUSP in complex with ICP0 | | 分子名称: | Ubiquitin E3 ligase ICP0, Ubiquitin carboxyl-terminal hydrolase 7 | | 著者 | Cheng, J, Li, Z, Gong, R, Fang, J, Yang, Y, Sun, C, Yang, H, Xu, Y. | | 登録日 | 2015-06-19 | | 公開日 | 2015-07-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.685 Å) | | 主引用文献 | Molecular mechanism for the substrate recognition of USP7.
Protein Cell, 6, 2015
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8D14
 | | Helical ADP-Pi-F-actin | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Reynolds, M.J, Alushin, G.M. | | 登録日 | 2022-05-26 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | | 主引用文献 | Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
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8D18
 | | Straight ADP-F-actin 2 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Reynolds, M.J, Alushin, G.M. | | 登録日 | 2022-05-26 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | | 主引用文献 | Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
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8D15
 | | Bent ADP-F-actin | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Reynolds, M.J, Alushin, G.M. | | 登録日 | 2022-05-26 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | | 主引用文献 | Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
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8D13
 | | Helical ADP-F-actin | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Reynolds, M.J, Alushin, G.M. | | 登録日 | 2022-05-26 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (2.43 Å) | | 主引用文献 | Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
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8D17
 | | Straight ADP-F-actin 1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Reynolds, M.J, Alushin, G.M. | | 登録日 | 2022-05-26 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | | 主引用文献 | Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
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8D16
 | | Bent ADP-Pi-F-actin | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Reynolds, M.J, Alushin, G.M. | | 登録日 | 2022-05-26 | | 公開日 | 2022-09-07 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | Bending forces and nucleotide state jointly regulate F-actin structure.
Nature, 611, 2022
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8VB1
 | | Crystal structure of HIV-1 protease with GS-9770 | | 分子名称: | (2S)-2-{(3M)-4-chloro-3-[1-(difluoromethyl)-1H-1,2,4-triazol-5-yl]phenyl}-2-[(2E,4R)-4-[4-(2-cyclopropyl-2H-1,2,3-triazol-4-yl)phenyl]-2-imino-5-oxo-4-(3,3,3-trifluoro-2,2-dimethylpropyl)imidazolidin-1-yl]ethyl [1-(difluoromethyl)cyclopropyl]carbamate, HIV-1 protease | | 著者 | Lansdon, E.B. | | 登録日 | 2023-12-11 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stability.
Antimicrob.Agents Chemother., 68, 2024
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7R94
 | | T-Plastin-F-actin complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Mei, L, Alushin, G.M. | | 登録日 | 2021-06-28 | | 公開日 | 2022-07-06 | | 最終更新日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural mechanism for bidirectional actin cross-linking by T-plastin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7SX8
 | | T-Plastin-F-actin complex, parallel bundled state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Mei, L, Reynolds, M.J, Alushin, G.M. | | 登録日 | 2021-11-22 | | 公開日 | 2022-08-31 | | 最終更新日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Structural mechanism for bidirectional actin cross-linking by T-plastin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7SX9
 | | T-Plastin-F-actin complex, anti-parallel bundled state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Mei, L, Reynolds, M.J, Alushin, G.M. | | 登録日 | 2021-11-22 | | 公開日 | 2022-08-31 | | 最終更新日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (10 Å) | | 主引用文献 | Structural mechanism for bidirectional actin cross-linking by T-plastin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7SXA
 | | T-Plastin-F-actin complex, pre-bundling intermediate state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Mei, L, Reynolds, M.J, Alushin, G.M. | | 登録日 | 2021-11-22 | | 公開日 | 2022-08-31 | | 最終更新日 | 2022-09-21 | | 実験手法 | ELECTRON MICROSCOPY (6.87 Å) | | 主引用文献 | Structural mechanism for bidirectional actin cross-linking by T-plastin.
Proc.Natl.Acad.Sci.USA, 119, 2022
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3N9M
 | | ceKDM7A from C.elegans, alone | | 分子名称: | FE (II) ION, Putative uncharacterized protein, ZINC ION | | 著者 | Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y. | | 登録日 | 2010-05-31 | | 公開日 | 2010-06-30 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.493 Å) | | 主引用文献 | Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
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3N9P
 | | ceKDM7A from C.elegans, complex with H3K4me3K27me2 peptide and NOG | | 分子名称: | FE (II) ION, Histone H3 peptide, N-OXALYLGLYCINE, ... | | 著者 | Yang, Y, Hu, L, Wang, P, Hou, H, Chen, C.D, Xu, Y. | | 登録日 | 2010-05-31 | | 公開日 | 2010-06-30 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.388 Å) | | 主引用文献 | Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans
Cell Res., 20, 2010
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